Author results

1HCP
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DNA RECOGNITION BY THE OESTROGEN RECEPTOR: FROM SOLUTION TO THE CRYSTAL
分子名称:HUMAN/CHICKEN ESTROGEN RECEPTOR, ZINC ION
著者Schwabe, J.W.R., Rhodes, D., Neuhaus, D.
登録日1993-11-23
公開日1995-11-23
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献DNA recognition by the oestrogen receptor: from solution to the crystal.
Structure, 1, 1993
1H9U
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THE STRUCTURE OF THE HUMAN RETINOID-X-RECEPTOR BETA LIGAND BINDING DOMAIN IN COMPLEX WITH THE SPECIFIC SYNTHETIC AGONIST LG100268
分子名称:RETINOID X RECEPTOR, BETA, 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID, ...
著者Schwabe, J.W.R., Love, J.D., Gooch, J.T.
登録日2001-03-21
公開日2002-04-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structural Basis for the Specificity of Retinoid-X Receptor-Selective Agonists: New Insights Into the Role of Helix H12
J.Biol.Chem., 277, 2002
1HG4
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ULTRASPIRACLE LIGAND BINDING DOMAIN FROM DROSOPHILA MELANOGASTER
分子名称:ULTRASPIRACLE, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE
著者Schwabe, J.W.R., Clayton, G.M.
登録日2000-12-12
公開日2001-02-23
最終更新日2015-02-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of the Ultraspiracle Ligand-Binding Domain Reveals a Nuclear Receptor Locked in an Inactive Conformation
Proc.Natl.Acad.Sci.USA, 98, 2001
1HCQ
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THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
分子名称:DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP*CP*CP*T P*G)-3'), DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (ESTROGEN RECEPTOR), ...
著者Schwabe, J.W.R., Chapman, L., Finch, J.T., Rhodes, D.
登録日1995-01-04
公開日1995-11-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements.
Cell(Cambridge,Mass.), 75, 1993
6G16
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STRUCTURE OF THE HUMAN RBBP4:MTA1(464-546) COMPLEX SHOWING LOOP EXCHANGE
分子名称:Histone-binding protein RBBP4, Metastasis-associated protein MTA1
著者Millard, C.J., Varma, N., Fairall, L., Schwabe, J.W.R.
登録日2018-03-20
公開日2018-06-13
最終更新日2018-08-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the human RBBP4:MTA1(464-546) complex showing loop exchange
To be published
1XC5
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SOLUTION STRUCTURE OF THE SMRT DEACETYLASE ACTIVATION DOMAIN
分子名称:Nuclear receptor corepressor 2
著者Codina, A., Love, J.D., Li, Y., Lazar, M.A., Neuhaus, D., Schwabe, J.W.R.
登録日2004-09-01
公開日2005-05-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors
Proc.Natl.Acad.Sci.Usa, 102, 2005
2VSR
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HPPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH 9-(S)-HODE
分子名称:PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid
著者Itoh, T., Fairall, L., Schwabe, J.W.R.
登録日2008-04-29
公開日2008-08-19
最終更新日2012-06-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
2VST
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HPPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH 13-(S)-HODE
分子名称:PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid
著者Itoh, T., Fairall, L., Schwabe, J.W.R.
登録日2008-04-29
公開日2008-08-19
最終更新日2012-06-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
2VV0
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HPPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH DHA
分子名称:PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID
著者Itoh, T., Fairall, L., Schwabe, J.W.R.
登録日2008-06-02
公開日2008-08-19
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
2VV1
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HPPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH 4-HDHA
分子名称:PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, (4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid
著者Itoh, T., Fairall, L., Schwabe, J.W.R.
登録日2008-06-02
公開日2008-08-19
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
2VV2
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HPPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH 5-HEPA
分子名称:PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, (5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid
著者Itoh, T., Fairall, L., Schwabe, J.W.R.
登録日2008-06-02
公開日2008-08-19
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
2VV3
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HPPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH 4-OXODHA
分子名称:PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, (6E,10Z,13Z,16Z,19Z)-4-oxodocosa-6,10,13,16,19-pentaenoic acid
著者Itoh, T., Fairall, L., Schwabe, J.W.R.
登録日2008-06-02
公開日2008-08-19
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Basis for the Activation of Ppargamma by Oxidized Fatty Acids.
Nat.Struct.Mol.Biol., 15, 2008
2VV4
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HPPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH 6-OXOOTE
分子名称:PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA, (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid, (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
著者Itoh, T., Fairall, L., Schwabe, J.W.R.
登録日2008-06-02
公開日2008-08-19
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for the Activation of Pparg by Oxidised Fatty Acids
Nat.Struct.Mol.Biol., 15, 2008
2XTC
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STRUCTURE OF THE TBL1 TETRAMERISATION DOMAIN
分子名称:F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
著者Oberoi, J., Fairall, L., Watson, P.J., Greenwood, J.A., Schwabe, J.W.R.
登録日2010-10-06
公開日2011-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTD
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STRUCTURE OF THE TBL1 TETRAMERISATION DOMAIN
分子名称:TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
著者Oberoi, J., Fairall, L., Watson, P.J., Greenwood, J.A., Schwabe, J.W.R.
登録日2010-10-06
公開日2011-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTE
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STRUCTURE OF THE TBL1 TETRAMERISATION DOMAIN
分子名称:F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
著者Oberoi, J., Fairall, L., Watson, P.J., Greenwood, J.A., Schwabe, J.W.R.
登録日2010-10-06
公開日2011-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2YHN
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THE IDOL-UBE2D COMPLEX MEDIATES STEROL-DEPENDENT DEGRADATION OF THE LDL RECEPTOR
分子名称:E3 UBIQUITIN-PROTEIN LIGASE MYLIP, ZINC ION
著者Fairall, L., Goult, B.T., Millard, C.J., Tontonoz, P., Schwabe, J.W.R.
登録日2011-05-04
公開日2011-06-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
4A69
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STRUCTURE OF HDAC3 BOUND TO COREPRESSOR AND INOSITOL TETRAPHOSPHATE
分子名称:HISTONE DEACETYLASE 3,, NUCLEAR RECEPTOR COREPRESSOR 2, ZINC ION, ...
著者Watson, P.J., Fairall, L., Santos, G.M., Schwabe, J.W.R.
登録日2011-11-01
公開日2012-01-11
最終更新日2012-01-25
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structure of Hdac3 Bound to Co-Repressor and Inositol Tetraphosphate.
Nature, 481, 2012
4BKX
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THE STRUCTURE OF HDAC1 IN COMPLEX WITH THE DIMERIC ELM2-SANT DOMAIN OF MTA1 FROM THE NURD COMPLEX
分子名称:METASTASIS-ASSOCIATED PROTEIN MTA1, HISTONE DEACETYLASE 1, ZINC ION, ...
著者Millard, C.J., Watson, P.J., Celardo, I., Gordiyenko, Y., Cowley, S.M., Robinson, C.V., Fairall, L., Schwabe, J.W.R.
登録日2013-04-30
公開日2013-07-03
最終更新日2013-07-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Class I Hdacs Share a Common Mechanism of Regulation by Inositol Phosphates.
Mol.Cell, 51, 2013
4CP3
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THE STRUCTURE OF BCL6 BTB (POZ) DOMAIN IN COMPLEX WITH THE ANSAMYCIN ANTIBIOTIC RIFABUTIN.
分子名称:B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN
著者Evans, S.E., Fairall, L., Goult, B.T., Jamieson, A.G., Ferrigno, P.K., Ford, R., Wagner, S.D., Schwabe, J.W.R.
登録日2014-01-31
公開日2014-03-19
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
Plos One, 9, 2014
4D6K
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STRUCTURE OF DNTTIP1 DIMERISATION DOMAIN.
分子名称:DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1
著者Itoh, T., Fairall, L., Schwabe, J.W.R.
登録日2014-11-11
公開日2015-02-18
最終更新日2015-03-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Functional Characterization of a Cell Cycle Associated Hdac1/2 Complex Reveals the Structural Basis for Complex Assembly and Nucleosome Targeting.
Nucleic Acids Res., 43, 2015
6GQF
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THE STRUCTURE OF MOUSE ASTERA (GRAMD1A) WITH 25-HYDROXY CHOLESTEROL
分子名称:GRAM domain-containing protein 1A, 25-HYDROXYCHOLESTEROL, GLYCEROL
著者Fairall, L., Gurnett, J.E., Vashi, D., Sandhu, J., Tontonoz, P., Schwabe, J.W.R.
登録日2018-06-07
公開日2018-09-26
最終更新日2018-10-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells.
Cell, 175, 2018
2MWI
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THE STRUCTURE OF THE CARBOXY-TERMINAL DOMAIN OF DNTTIP1
分子名称:Deoxynucleotidyltransferase terminal-interacting protein 1
著者Schwabe, J.W.R., Muskett, F.W., Itoh, T.
登録日2014-11-11
公開日2015-02-18
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.
Nucleic Acids Res., 43, 2015
1ZFD
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SWI5 ZINC FINGER DOMAIN 2, NMR, 45 STRUCTURES
分子名称:SWI5, ZINC ION
著者Neuhaus, D., Nakaseko, Y., Schwabe, J.W.R., Rhodes, D., Klug, A.
登録日1996-04-04
公開日1996-10-14
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structures of two zinc-finger domains from SWI5 obtained using two-dimensional 1H nuclear magnetic resonance spectroscopy. A zinc-finger structure with a third strand of beta-sheet.
J.Mol.Biol., 228, 1992
2DRP
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THE CRYSTAL STRUCTURE OF A TWO ZINC-FINGER PEPTIDE REVEALS AN EXTENSION TO THE RULES FOR ZINC-FINGER/DNA RECOGNITION
分子名称:DNA (5'-D(*CP*TP*AP*AP*TP*AP*AP*GP*GP*AP*TP*AP*AP*CP*GP*TP*C P*CP*G)-3'), DNA (5'-D(*TP*CP*GP*GP*AP*CP*GP*TP*TP*AP*TP*CP*CP*TP*TP*AP*T P*TP*A)-3'), PROTEIN (TRAMTRACK DNA-BINDING DOMAIN), ...
著者Fairall, L., Schwabe, J.W.R., Chapman, L., Finch, J.T., Rhodes, D.
登録日1994-06-06
公開日1994-08-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition.
Nature, 366, 1993
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