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4WCI
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BU of 4wci by Molmil
Crystal structure of the 1st SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 378-393) from human RIN3
Descriptor: CD2-associated protein, Ras and Rab interactor 3, SULFATE ION
Authors:Rouka, E, Simister, P.C, Janning, M, Kirsch, K.H, Krojer, T, Knapp, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Feller, S.M, Structural Genomics Consortium (SGC)
Deposit date:2014-09-04
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).
J.Biol.Chem., 290, 2015
3U23
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BU of 3u23 by Molmil
Atomic resolution crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide from human RIN3
Descriptor: 1,2-ETHANEDIOL, CD2-associated protein, Ras and Rab interactor 3
Authors:Simister, P.C, Rouka, E, Janning, M, Muniz, J.R.C, Kirsch, K.H, Knapp, S, von Delft, F, Filippakopoulos, P, Arrowsmith, C.H, Krojer, T, Edwards, A.M, Weigelt, J, Bountra, C, Feller, S.M, Structural Genomics Consortium (SGC)
Deposit date:2011-09-30
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).
J.Biol.Chem., 290, 2015
1OEB
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BU of 1oeb by Molmil
Mona/Gads SH3C domain
Descriptor: CADMIUM ION, GRB2-RELATED ADAPTOR PROTEIN 2, LYMPHOCYTE CYTOSOLIC PROTEIN 2
Authors:Harkiolaki, M, Lewitzky, M, Gilbert, R.J.C, Jones, E.Y, Bourette, R.P, Mouchiroud, G, Sondermann, H, Moarefi, I, Feller, S.M.
Deposit date:2003-03-24
Release date:2003-04-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Basis for SH3 Domain-Mediated High-Affinity Binding between Mona/Gads and Slp-76
Embo J., 22, 2003
3RNJ
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BU of 3rnj by Molmil
Crystal structure of the SH3 domain from IRSp53 (BAIAP2)
Descriptor: 1,2-ETHANEDIOL, Brain-specific angiogenesis inhibitor 1-associated protein 2, ISOPROPYL ALCOHOL, ...
Authors:Simister, P.C, Barilari, M, Muniz, J.R.C, Dente, L, Knapp, S, von Delft, F, Filippakopoulos, P, Vollmar, M, Chaikuad, A, Raynor, J, Tregubova, A, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Feller, S.M, Structural Genomics Consortium (SGC)
Deposit date:2011-04-22
Release date:2011-05-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the SH3 domain from IRSp53 (BAIAP2)
To be Published
4X1V
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BU of 4x1v by Molmil
Crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 76-91) from human ARAP1
Descriptor: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1, CD2-associated protein
Authors:Rouka, E, Krojer, T, von Delft, F, Knapp, S, Kirsch, K.H, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Feller, S.M, Simister, P.C.
Deposit date:2014-11-25
Release date:2016-02-17
Last modified:2016-02-24
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide (aa 76-91) from human ARAP1
to be published
2BZX
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BU of 2bzx by Molmil
Atomic model of CrkL-SH3C monomer
Descriptor: CRK-LIKE PROTEIN
Authors:Harkiolaki, M, Gilbert, R.J, Jones, E.Y, Feller, S.M.
Deposit date:2005-08-24
Release date:2006-09-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The C-Terminal SH3 Domain of Crkl as a Dynamic Dimerization Module Transiently Exposing a Nuclear Export Signal.
Structure, 14, 2006
2BZY
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BU of 2bzy by Molmil
Homodimer of CrkL-SH3C domain
Descriptor: CRK-LIKE PROTEIN
Authors:Harkiolaki, M, Gilbert, R.J, Jones, E.Y, Feller, S.M.
Deposit date:2005-08-24
Release date:2006-09-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The C-Terminal SH3 Domain of Crkl as a Dynamic Dimerization Module Transiently Exposing a Nuclear Export Signal.
Structure, 14, 2006
1UTI
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BU of 1uti by Molmil
Mona/Gads SH3C in complex with HPK derived peptide
Descriptor: GRB2-RELATED ADAPTOR PROTEIN 2, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 1
Authors:Lewitzky, M, Harkiolaki, M, Domart, M.C, Feller, S.M.
Deposit date:2003-12-09
Release date:2004-05-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mona/Gads Sh3C Binding to Hematopoietic Progenitor Kinase 1 (Hpk1) Combines an Atypical SH3 Binding Motif, R/Kxxk, with a Classical Pxxp Motif Embedded in a Polyproline Type II (Ppii) Helix
J.Biol.Chem., 279, 2004
2W10
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BU of 2w10 by Molmil
Mona SH3C in complex
Descriptor: GRB2-RELATED ADAPTOR PROTEIN 2, PHOSPHATE ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23
Authors:Harkiolaki, M, Feller, S.M.
Deposit date:2008-10-13
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2VWF
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BU of 2vwf by Molmil
Grb2 SH3C (2)
Descriptor: GRB2-ASSOCIATED-BINDING PROTEIN 2, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Harkiolaki, M, Tsirka, T, Feller, S.M.
Deposit date:2008-06-24
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2VVK
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BU of 2vvk by Molmil
Grb2 SH3C (1)
Descriptor: GLYCEROL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Harkiolaki, M, Tsirka, T, Feller, S.M.
Deposit date:2008-06-09
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2W0Z
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BU of 2w0z by Molmil
Grb2 SH3C (3)
Descriptor: GRB2-ASSOCIATED-BINDING PROTEIN 2, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Harkiolaki, M, Tsirka, T, Feller, S.M.
Deposit date:2008-10-13
Release date:2009-05-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
1CKB
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BU of 1ckb by Molmil
STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK
Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, SOS PEPTIDE (PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-ARG)
Authors:Wu, X, Kuriyan, J.
Deposit date:1995-01-24
Release date:1995-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk.
Structure, 3, 1995
1CKA
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BU of 1cka by Molmil
STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK
Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, C3G PEPTIDE (PRO-PRO-PRO-ALA-LEU-PRO-PRO-LYS-LYS-ARG)
Authors:Wu, X, Kuriyan, J.
Deposit date:1995-01-24
Release date:1995-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk.
Structure, 3, 1995
1WA7
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BU of 1wa7 by Molmil
SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND
Descriptor: HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1), TYROSINE-PROTEIN KINASE LYN
Authors:Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H.
Deposit date:2004-10-25
Release date:2005-07-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck.
Biochemistry, 41, 2002
1H92
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SH3 domain of human Lck tyrosine kinase
Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK
Authors:Schweimer, K, Hoffmann, S, Friedrich, U, Biesinger, B, Roesch, P, Sticht, H.
Deposit date:2001-02-22
Release date:2001-10-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck
Biochemistry, 41, 2002

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