Author results

2MCY
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CR1 SUSHI DOMAINS 2 AND 3
分子名称:Complement receptor type 1
著者Park, H.J., Guariento, M.J., Maciejewski, M., Hauart, R., Tham, W., Cowman, A.F., Schmidt, C.Q., Martens, H., Liszewski, K.M., Hourcade, D., Barlow, P.N., Atkinson, J.P.
登録日2013-08-27
公開日2013-11-13
最終更新日2014-01-22
実験手法SOLUTION NMR
主引用文献Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
2MCZ
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CR1 SUSHI DOMAINS 1 AND 2
分子名称:Complement receptor type 1
著者Park, H.J., Guariento, M.J., Maciejewski, M., Hauart, R., Tham, W., Cowman, A.F., Schmidt, C.Q., Martens, H., Liszewski, K.M., Hourcade, D., Barlow, P.N., Atkinson, J.P.
登録日2013-08-27
公開日2013-11-13
最終更新日2014-01-22
実験手法SOLUTION NMR
主引用文献Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
3VUU
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CRYSTAL STRUCTURE OF THE MEROZOITE SURFACE PROTEIN MSPDBL2 FROM P. FALCIPARUM
分子名称:Erythrocyte membrane protein, putative, CHLORIDE ION
著者Czabotar, P.E., Hodder, A.N., Clarke, O.B., Lin, C.S., Smith, B.J., Cowman, A.F.
登録日2012-07-09
公開日2012-08-08
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum
J.Biol.Chem., 287, 2012
3VUV
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CRYSTAL STRUCTURE OF THE MEROZOITE SURFACE PROTEIN MSPDBL2 FROM P. FALCIPARUM BOUND TO ZINC
分子名称:Erythrocyte membrane protein, putative, ZINC ION
著者Czabotar, P.E., Hodder, A.N., Clarke, O.B., Lin, C.S., Smith, B.J., Cowman, A.F.
登録日2012-07-09
公開日2012-08-08
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (2.114 Å)
主引用文献Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum
J.Biol.Chem., 287, 2012
4ZL4
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PLASMEPSIN V FROM PLASMODIUM VIVAX BOUND TO A TRANSITION STATE MIMETIC (WEHI-842)
分子名称:Aspartic protease PM5, N-[(benzyloxy)carbonyl]-O-carbamimidamido-L-homoseryl-N-{(3S,4S)-3-hydroxy-6-methyl-1-oxo-1-[(2-phenylethyl)amino]heptan-4-yl}-L-valinamide, SULFATE ION, ...
著者Czabotar, P.E., Hodder, A.N., Smith, B.J., Sleebs, B.E., Gazdic, M., Boddey, J.A., Cowman, A.F.
登録日2015-05-01
公開日2015-07-15
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes.
Nat.Struct.Mol.Biol., 22, 2015
5TIH
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STRUCTURAL BASIS FOR INHIBITION OF ERYTHROCYTE INVASION BY ANTIBODIES TO PLASMODIUM FALCIPARUM PROTEIN CYRPA
分子名称:Cysteine-rich protective antigen, CyRPA antibody Fab Heavy Chain, CyRPA antibody Fab Light Chain, ...
著者Chen, L., Xu, Y., Wang, W., Thompson, J.K., Goddard-Borger, E., Lawrence, M.C., Cowman, A.F.
登録日2016-10-03
公開日2017-03-01
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA.
Elife, 6, 2017
5TIK
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STRUCTURAL BASIS FOR INHIBITION OF ERYTHROCYTE INVASION BY ANTIBODIES TO PLASMODIUM FALCIPARUM PROTEIN CYRPA
分子名称:Cysteine-rich protective antigen
著者Chen, L., Xu, Y., Wang, W., Thompson, J.K., Goddard-Borger, E., Lawrence, M.C., Cowman, A.F.
登録日2016-10-03
公開日2017-03-01
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA.
Elife, 6, 2017
6C4G
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PLASMEPSIN V FROM PLASMODIUM VIVAX BOUND TO A TRANSITION STATE MIMETIC (WEHI-601)
分子名称:Aspartic protease PM5, N-ACETYL-D-GLUCOSAMINE, benzyl [(6S,7S,10S,13S,18Z)-18-amino-10-cyclohexyl-6-hydroxy-18-imino-7-(2-methylpropyl)-4,9,12-trioxo-1-phenyl-16-oxa-3,8,11,17-tetraazaoctadecan-13-yl]carbamate, ...
著者Czabotar, P.E., Hodder, A.N., Nguyen, W., Sleebs, B.E., Boddey, J.A., Cowman, A.F.
登録日2018-01-11
公開日2018-06-13
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P2position of PEXEL peptidomimetics.
Eur J Med Chem, 154, 2018
6MPV
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF PLASMODIUM FALCIPARUM RH5/CYRPA/RIPR INVASION COMPLEX
分子名称:Cysteine-rich protective antigen, Reticulocyte binding protein 5, PfRipr
著者Wilson, W., Zhiheng, Y., Cowman, A.F.
登録日2018-10-08
公開日2018-12-12
最終更新日2019-01-16
実験手法ELECTRON MICROSCOPY (7.17 Å)
主引用文献Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex.
Nature, 565, 2019
4WAT
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CRYSTAL STRUCTURE OF PFRH5, AN ESSENTIAL P. FALCIPARUM LIGAND FOR INVASION OF HUMAN ERYTHROCYTES
分子名称:PfRh5, N-ACETYL-D-GLUCOSAMINE, IMIDAZOLE
著者Chen, L.
登録日2014-09-01
公開日2014-10-22
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes.
Elife, 3, 2014
5UMD
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STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO THE ANTIMALARIAL DRUG MEFLOQUINE
分子名称:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Wong, W., Bai, X.-C., Brown, A., Scheres, S., Baum, J.
登録日2017-01-27
公開日2017-03-01
最終更新日2018-10-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.
Nat Microbiol, 2, 2017
6BPA
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PLASMODIUM VIVAX RETICULOCYTE BINDING PROTEIN 2B (PVRBP2B) BOUND TO MONOCLONAL ANTIBODY 3E9
分子名称:Reticulocyte binding protein 2, putative, Monoclonal antibody 3E9 Fab heavy chain, ...
著者Gruszczyk, J., Chan, L.J., Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2018-07-18
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPB
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PLASMODIUM VIVAX INVASION BLOCKING MONOCLONAL ANTIBODY 4F7
分子名称:Monoclonal antibody 4F7 Fab heavy chain, Monoclonal antibody 4F7 Fab light chain
著者Gruszczyk, J., Chan, L.J., Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2018-07-18
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPC
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PLASMODIUM VIVAX RETICULOCYTE BINDING PROTEIN 2B (PVRBP2B) BOUND TO MONOCLONAL ANTIBODY 4F7
分子名称:Reticulocyte binding protein 2, putative, Monoclonal antibody 4F7 Fab heavy chain, ...
著者Gruszczyk, J., Chan, L.J., Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2018-07-18
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPD
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PLASMODIUM VIVAX INVASION BLOCKING MONOCLONAL ANTIBODY 10B12
分子名称:Monoclonal antibody 10B12 Fab heavy chain, Monoclonal antibody 10B12 Fab light chain
著者Gruszczyk, J., Chan, L.J., Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2018-07-18
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6BPE
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PLASMODIUM VIVAX RETICULOCYTE BINDING PROTEIN 2B (PVRBP2B) BOUND TO MONOCLONAL ANTIBODY 6H1
分子名称:Reticulocyte binding protein 2, putative, Monoclonal antibody 6H1 Fab heavy chain, ...
著者Gruszczyk, J., Chan, L.J., Tham, W.H.
登録日2017-11-22
公開日2018-06-20
最終更新日2018-07-18
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6D03
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CRYO-EM STRUCTURE OF A PLASMODIUM VIVAX INVASION COMPLEX ESSENTIAL FOR ENTRY INTO HUMAN RETICULOCYTES; ONE MOLECULE OF PARASITE LIGAND.
分子名称:Transferrin receptor protein 1, Serotransferrin, Reticulocyte binding protein 2, ...
著者Gruszczyk, J., Huang, R.K., Hong, C., Yu, Z., Tham, W.H.
登録日2018-04-10
公開日2018-06-20
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6D04
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CRYO-EM STRUCTURE OF A PLASMODIUM VIVAX INVASION COMPLEX ESSENTIAL FOR ENTRY INTO HUMAN RETICULOCYTES; TWO MOLECULES OF PARASITE LIGAND, SUBCLASS 1.
分子名称:Transferrin receptor protein 1, Serotransferrin, Reticulocyte binding protein 2, ...
著者Gruszczyk, J., Huang, R.K., Hong, C., Yu, Z., Tham, W.H.
登録日2018-04-10
公開日2018-06-20
最終更新日2018-07-11
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018
6D05
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CRYO-EM STRUCTURE OF A PLASMODIUM VIVAX INVASION COMPLEX ESSENTIAL FOR ENTRY INTO HUMAN RETICULOCYTES; TWO MOLECULES OF PARASITE LIGAND, SUBCLASS 2.
分子名称:Transferrin receptor protein 1, Serotransferrin, Reticulocyte binding protein 2, ...
著者Gruszczyk, J., Huang, R.K., Hong, C., Yu, Z., Tham, W.H.
登録日2018-04-10
公開日2018-06-20
最終更新日2018-07-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of an essential Plasmodium vivax invasion complex.
Nature, 559, 2018