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1B3B
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BU of 1b3b by Molmil
THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT N97D, G376K
Descriptor: PROTEIN (GLUTAMATE DEHYDROGENASE)
Authors:Knapp, S, Lebbink, J.H.G, Van Der Oost, J, Devos, W.M, Rice, D, Ladenstein, R.
Deposit date:1998-12-07
Release date:1999-12-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. I. Introduction of a six-residue ion-pair network in the hinge region.
J.Mol.Biol., 280, 1998
5NG6
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BU of 5ng6 by Molmil
Crystal structure of FnCas12a bound to a crRNA
Descriptor: CRISPR-associated endonuclease Cpf1, MAGNESIUM ION, crRNA
Authors:Swarts, D.C, van der Oost, J, Jinek, M.
Deposit date:2017-03-16
Release date:2017-06-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.342 Å)
Cite:Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
6QZK
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BU of 6qzk by Molmil
Structure of Clostridium butyricum Argonaute bound to a guide DNA (5' deoxycytidine) and a 19-mer target DNA
Descriptor: Clostridium butyricum Argonaute, DNA target (5'-D(T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*T)-3'), FORMIC ACID, ...
Authors:Swarts, D.C, Jinek, M, Hegge, J.W, Van der Oost, J.
Deposit date:2019-03-11
Release date:2019-04-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.548 Å)
Cite:DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute.
Nucleic Acids Res., 47, 2019
5FRD
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BU of 5frd by Molmil
Structure of a thermophilic esterase
Descriptor: CARBOXYLESTERASE (EST-2), CHLORIDE ION, CITRATE ANION, ...
Authors:Sayer, C, Finnigan, W, Isupov, M.N, Levisson, M, Kengen, S.W.M, van der Oost, J, Harmer, N, Littlechild, J.A.
Deposit date:2015-12-17
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and Biochemical Characterisation of Archaeoglobus Fulgidus Esterase Reveals a Bound Coa Molecule in the Vicinity of the Active Site.
Sci.Rep., 6, 2016
1I9B
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BU of 1i9b by Molmil
X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETYLCHOLINE BINDING PROTEIN, CALCIUM ION
Authors:Brejc, K, van Dijk, W.J, Klaassen, R, Schuurmans, M, van der Oost, J, Smit, A.B, Sixma, T.K.
Deposit date:2001-03-18
Release date:2001-05-16
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors.
Nature, 411, 2001
5NFV
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BU of 5nfv by Molmil
Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CRISPR-associated endonuclease Cpf1, DNA non-target strand, ...
Authors:Swarts, D.C, van der Oost, J, Jinek, M.
Deposit date:2017-03-16
Release date:2017-06-14
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
3JUR
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BU of 3jur by Molmil
The crystal structure of a hyperthermoactive Exopolygalacturonase from Thermotoga maritima
Descriptor: Exo-poly-alpha-D-galacturonosidase
Authors:Pijning, T, van Pouderoyen, G, Kluskens, L.D, van der Oost, J, Dijkstra, B.W.
Deposit date:2009-09-15
Release date:2009-11-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The crystal structure of a hyperthermoactive exopolygalacturonase from Thermotoga maritima reveals a unique tetramer
Febs Lett., 2009
2CG4
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BU of 2cg4 by Molmil
Structure of E.coli AsnC
Descriptor: ASPARAGINE, MAGNESIUM ION, REGULATORY PROTEIN ASNC
Authors:Thaw, P, Sedelnikova, S.E, Muranova, T, Wiese, S, Ayora, S, Alonso, J.C, Brinkman, A.B, Akerboom, J, van der Oost, J, Rafferty, J.B.
Deposit date:2006-02-27
Release date:2006-04-04
Last modified:2021-04-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insight Into Gene Transcriptional Regulation and Effector Binding by the Lrp/Asnc Family.
Nucleic Acids Res., 34, 2006
2HTN
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BU of 2htn by Molmil
E. coli bacterioferritin in its as-isolated form
Descriptor: Bacterioferritin, FE (III) ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:van Eerde, A, Wolterink-Van Loo, S, Van Der Oost, J, Dijkstra, B.W.
Deposit date:2006-07-26
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Fortuitous structure determination of 'as-isolated' Escherichia coli bacterioferritin in a novel crystal form.
Acta Crystallogr.,Sect.F, 62, 2006
1I1G
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BU of 1i1g by Molmil
CRYSTAL STRUCTURE OF THE LRP-LIKE TRANSCRIPTIONAL REGULATOR FROM THE ARCHAEON PYROCOCCUS FURIOSUS
Descriptor: TRANSCRIPTIONAL REGULATOR LRPA
Authors:Leonard, P.M, Smits, S.H.J, Sedelnikova, S.E, Brinkman, A.B, de Vos, W.M, van der Oost, J, Rice, D.W, Rafferty, J.B.
Deposit date:2001-02-01
Release date:2002-02-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus.
EMBO J., 20, 2001
3DOH
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BU of 3doh by Molmil
Crystal Structure of a Thermostable Esterase
Descriptor: SULFATE ION, esterase
Authors:Levisson, M, Sun, L, Hendriks, S, Dijkstra, B.W, Van der Oost, J, Kengen, S.W.M.
Deposit date:2008-07-04
Release date:2009-02-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain.
J.Mol.Biol., 385, 2009
3DOI
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BU of 3doi by Molmil
Crystal Structure of a Thermostable Esterase complex with paraoxon
Descriptor: DIETHYL PHOSPHONATE, esterase
Authors:Levisson, M, Sun, L, Hendriks, S, Dijkstra, B.W, Van der Oost, J, Kengen, S.W.M.
Deposit date:2008-07-04
Release date:2009-02-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain.
J.Mol.Biol., 385, 2009
2H6E
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BU of 2h6e by Molmil
Crystal structure of the D-arabinose dehydrogenase from Sulfolobus solfataricus
Descriptor: D-arabinose 1-dehydrogenase, ZINC ION
Authors:Brouns, S.J.J, Turnbull, A.P, Akerboom, J, Willemen, H.L.D.M, De Vos, W.M, Van der Oost, J.
Deposit date:2006-05-31
Release date:2007-06-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure and Biochemical Properties of the d-Arabinose Dehydrogenase from Sulfolobus solfataricus
J.Mol.Biol., 371, 2007
1X82
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BU of 1x82 by Molmil
CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE FROM PYROCOCCUS FURIOSUS WITH BOUND 5-phospho-D-arabinonate
Descriptor: 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase
Authors:Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J.
Deposit date:2004-08-17
Release date:2004-10-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1X7N
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BU of 1x7n by Molmil
The crystal structure of Pyrococcus furiosus phosphoglucose isomerase with bound 5-phospho-D-arabinonate and Manganese
Descriptor: 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase, MANGANESE (II) ION
Authors:Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J.
Deposit date:2004-08-16
Release date:2004-10-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1X8E
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BU of 1x8e by Molmil
Crystal structure of Pyrococcus furiosus phosphoglucose isomerase free enzyme
Descriptor: Glucose-6-phosphate isomerase
Authors:Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J.
Deposit date:2004-08-18
Release date:2004-10-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
1XRK
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BU of 1xrk by Molmil
Crystal structure of a mutant bleomycin binding protein from Streptoalloteichus hindustanus displaying increased thermostability
Descriptor: BLEOMYCIN A2, Bleomycin resistance protein, SULFATE ION
Authors:Brouns, S.J.J, Wu, H, Akerboom, J, Turnbull, A.P, de Vos, W.M, Van der Oost, J.
Deposit date:2004-10-15
Release date:2005-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Engineering a selectable marker for hyperthermophiles
J.Biol.Chem., 280, 2005
4Q2C
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BU of 4q2c by Molmil
Crystal structure of CRISPR-associated protein
Descriptor: CRISPR-associated helicase Cas3, NICKEL (II) ION
Authors:Gong, B, Shin, M, Sun, J, van der Oost, J, Kim, J.-S.
Deposit date:2014-04-07
Release date:2014-11-19
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q2D
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BU of 4q2d by Molmil
Crystal Structure of CRISPR-Associated protein in complex with 2'-Deoxyadenosine 5'-Triphosphate
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CRISPR-associated helicase Cas3, MAGNESIUM ION, ...
Authors:Gong, B, Shin, M, Sun, J, van der Oost, J, Kim, J.-S.
Deposit date:2014-04-07
Release date:2014-11-19
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.771 Å)
Cite:Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3.
Proc.Natl.Acad.Sci.USA, 111, 2014
2QTF
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BU of 2qtf by Molmil
Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus
Descriptor: ACETATE ION, CADMIUM ION, GTP-binding protein, ...
Authors:Wu, H, Sun, L, Brouns, S.J, Fu, S, Rao, Z, Van der Oost, J.
Deposit date:2007-08-02
Release date:2008-08-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.
To be Published
2QTH
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BU of 2qth by Molmil
Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus in complex with GDP
Descriptor: ACETATE ION, CADMIUM ION, GTP-binding protein, ...
Authors:Wu, H, Sun, L, Brouns, S.J, Fu, S, Rao, Z, Van der Oost, J.
Deposit date:2007-08-02
Release date:2008-08-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.
To be Published
2TMG
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BU of 2tmg by Molmil
THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT S128R, T158E, N117R, S160E
Descriptor: PROTEIN (GLUTAMATE DEHYDROGENASE)
Authors:Knapp, S, Lebbink, J.H.G, van der Oost, J, de Vos, W.M, Rice, D, Ladenstein, R.
Deposit date:1998-12-04
Release date:1999-12-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface.
J.Mol.Biol., 289, 1999
1R6V
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BU of 1r6v by Molmil
Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin
Descriptor: CALCIUM ION, subtilisin-like serine protease
Authors:Kim, J.S, Kluskens, L.D, de Vos, W.M, Huber, R, van der Oost, J.
Deposit date:2003-10-17
Release date:2004-10-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin.
J.Mol.Biol., 335, 2004
1S4E
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BU of 1s4e by Molmil
Pyrococcus furiosus galactokinase in complex with galactose, ADP and magnesium
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Galactokinase, MAGNESIUM ION, ...
Authors:Hartley, A, Glynn, S.E, Barynin, V, Baker, P.J, Sedelnikova, S.E, Verhees, C, de Geus, D, van der Oost, J, Timson, D.J, Reece, R.J, Rice, D.W.
Deposit date:2004-01-16
Release date:2004-04-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Substrate specificity and mechanism from the structure of Pyrococcus furiosus galactokinase
J.Mol.Biol., 337, 2004
8HHM
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BU of 8hhm by Molmil
Cryo-EM structure of the Cas12m2-crRNA-target DNA ternary complex intermediate state
Descriptor: Cas12m2, DNA (36-MER), GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023

 

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