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8IFJ
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BU of 8ifj by Molmil
Crystal structure of pyrrolysyl-tRNA synthetase from methanogenic archaeon ISO4-G1
Descriptor: Pyrrolysyl-tRNA synthetase PylS
Authors:Yanagisawa, T, Tanabe, H, Yokoyama, S.
Deposit date:2023-02-18
Release date:2023-03-15
Last modified:2023-04-26
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Crystal Structure of Pyrrolysyl-tRNA Synthetase from a Methanogenic Archaeon ISO4-G1 and Its Structure-Based Engineering for Highly-Productive Cell-Free Genetic Code Expansion with Non-Canonical Amino Acids.
Int J Mol Sci, 24, 2023
3VQV
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BU of 3vqv by Molmil
Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with AMPPNP (re-refined)
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pyrrolysine--tRNA ligase
Authors:Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2012-04-01
Release date:2013-01-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site
Acta Crystallogr.,Sect.D, 69, 2013
2EL7
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BU of 2el7 by Molmil
Crystal structure of Tryptophanyl-tRNA synthetase from Thermus thermophilus
Descriptor: PHOSPHATE ION, Tryptophanyl-tRNA synthetase
Authors:Yanagisawa, T, Sumida, T, Ishii, R, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-26
Release date:2008-03-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Tryptophanyl-tRNA synthetase from Thermus thermophilus
To be published
2E3C
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BU of 2e3c by Molmil
Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase
Descriptor: Pyrrolysyl-tRNA synthetase
Authors:Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-11-22
Release date:2007-12-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase
J.Mol.Biol., 378, 2008
2ZCE
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BU of 2zce by Molmil
Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with pyrrolysine and an ATP analogue
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PYRROLYSINE, ...
Authors:Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-11-08
Release date:2008-04-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase
J.Mol.Biol., 378, 2008
2ZIN
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BU of 2zin by Molmil
Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with BocLys and an ATP analogue
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, N~6~-(tert-butoxycarbonyl)-L-lysine, ...
Authors:Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-02-19
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode N(varepsilon)-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification
Chem.Biol., 15, 2008
2ZIO
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BU of 2zio by Molmil
Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with AlocLys-AMP and PNP
Descriptor: 5'-O-[(S)-({(2S)-2-amino-6-[(propoxycarbonyl)amino]hexanoyl}oxy)(hydroxy)phosphoryl]adenosine, IMIDODIPHOSPHORIC ACID, Pyrrolysyl-tRNA synthetase
Authors:Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-02-19
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode N(varepsilon)-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification
Chem.Biol., 15, 2008
2EL9
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BU of 2el9 by Molmil
Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue
Descriptor: 5'-O-[(L-HISTIDYLAMINO)SULFONYL]ADENOSINE, Histidyl-tRNA synthetase
Authors:Yanagisawa, T, Si, S.Y, Matsuno, M, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-27
Release date:2008-03-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue
To be published
3VQX
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BU of 3vqx by Molmil
Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in triclinic crystal form
Descriptor: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Pyrrolysine--tRNA ligase, ...
Authors:Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2012-04-02
Release date:2013-01-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site
Acta Crystallogr.,Sect.D, 69, 2013
3VQY
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BU of 3vqy by Molmil
Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with BocLys and AMPPNP (form 2)
Descriptor: MAGNESIUM ION, N~6~-(tert-butoxycarbonyl)-L-lysine, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2012-04-02
Release date:2013-01-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site
Acta Crystallogr.,Sect.D, 69, 2013
3VQW
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BU of 3vqw by Molmil
Crystal structure of the SeMet substituted catalytic domain of pyrrolysyl-tRNA synthetase
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pyrrolysine--tRNA ligase
Authors:Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2012-04-01
Release date:2013-01-02
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site
Acta Crystallogr.,Sect.D, 69, 2013
3WNC
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BU of 3wnc by Molmil
Crystal structure of EF-Pyl in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translation elongation factor 1A
Authors:Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2013-12-08
Release date:2014-12-10
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).
J. Struct. Funct. Genomics, 16, 2015
3WNB
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BU of 3wnb by Molmil
Crystal structure of EF-Pyl in complex with GMPPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein translation elongation factor 1A
Authors:Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2013-12-08
Release date:2014-12-10
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).
J. Struct. Funct. Genomics, 16, 2015
3WND
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BU of 3wnd by Molmil
Crystal structure of EF-Pyl
Descriptor: CITRIC ACID, Protein translation elongation factor 1A
Authors:Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2013-12-08
Release date:2014-12-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).
J. Struct. Funct. Genomics, 16, 2015
6ABK
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BU of 6abk by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TeocLys
Descriptor: (2S)-2-azanyl-6-(trimethylsilylmethoxycarbonylamino)hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-22
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AAO
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BU of 6aao by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TCO*Lys
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-18
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.403 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AB0
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BU of 6ab0 by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pAmPyLys
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N6-{[(6-aminopyridin-3-yl)methoxy]carbonyl}-L-lysine, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-19
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.441 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AAP
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BU of 6aap by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with ZaeSeCys
Descriptor: 3-[(2-{[(benzyloxy)carbonyl]amino}ethyl)selanyl]-L-alanine, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-18
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AAD
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BU of 6aad by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mTmdZLys
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N6-[({3-[3-(trifluoromethyl)-3H-diaziren-3-yl]phenyl}methoxy)carbonyl]-L-lysine, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-18
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.444 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AAQ
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BU of 6aaq by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with BCNLys
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N6-({[(1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl]methoxy}carbonyl)-L-lysine, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-18
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.551 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AAN
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BU of 6aan by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mEtZLys
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-18
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AAC
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BU of 6aac by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mAzZLys
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-18
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.479 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AB1
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BU of 6ab1 by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oAzZLys
Descriptor: (2S)-2-azanyl-6-[(2-azidophenyl)methoxycarbonylamino]hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-19
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.381 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6ABL
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BU of 6abl by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oBrZLys
Descriptor: (2S)-2-azanyl-6-[(2-bromophenyl)methoxycarbonylamino]hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-22
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6ABM
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BU of 6abm by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pTmdZLys
Descriptor: (2S)-2-azanyl-6-[[4-[3-(trifluoromethyl)-1,2-diazirin-3-yl]phenyl]methoxycarbonylamino]hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-22
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.368 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019

 

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