Author results

3KCU
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STRUCTURE OF FORMATE CHANNEL
Descriptor:Probable formate transporter 1, 2-(6-(2-CYCLOHEXYLETHOXY)-TETRAHYDRO-4,5-DIHYDROXY-2(HYDROXYMETHYL)-2H-PYRAN-3-YLOXY)-TETRAHYDRO-6(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL
Authors:Wang, Y., Huang, Y., Wang, J., Yan, N., Shi, Y.
Deposit date:2009-10-22
Release date:2009-12-01
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.243 Å)
Cite:Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
3KCV
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STRUCTURE OF FORMATE CHANNEL
Descriptor:Probable formate transporter 1
Authors:Wang, Y., Huang, Y., Wang, J., Yan, N., Shi, Y.
Deposit date:2009-10-22
Release date:2009-12-01
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (3.198 Å)
Cite:Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
6K3H
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CRYSTALLOGRAPHIC ANALYSIS OF NUCLEOSIDE DIPHOSPHATE KINASE (NDK) FROM ASPERGILLUS FLAVUS
Descriptor:Nucleoside diphosphate kinase
Authors:Wang, Y., Wang, S., Wang, S.H.
Deposit date:2019-05-18
Release date:2019-07-03
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.179 Å)
Cite:Molecular and structural basis of nucleoside diphosphate kinase-mediated regulation of spore and sclerotia development in the fungusAspergillus flavus.
J.Biol.Chem., 2019
3GX8
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF YEAST MONOTHIOL GLUTAREDOXIN GRX5
Descriptor:Monothiol glutaredoxin-5, mitochondrial, SULFATE ION
Authors:Wang, Y., He, Y.X., Yu, J., Xiong, Y., Chen, Y., Zhou, C.Z.
Deposit date:2009-04-01
Release date:2010-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.673 Å)
Cite:Structural and biochemical characterization of yeast monothiol glutaredoxin Grx5
To be Published
4ZHQ
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-MMAE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta chain, Stathmin-4, ...
Authors:Wang, Y., Zhang, R.
Deposit date:2015-04-26
Release date:2016-07-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
4ZI7
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-HTI286 COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta chain, Stathmin-4, ...
Authors:Wang, Y., Zhang, R.
Deposit date:2015-04-27
Release date:2016-07-27
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
4ZOL
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-TUBULYSIN M COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta chain, Stathmin-4, ...
Authors:Wang, Y., Zhang, R.
Deposit date:2015-05-06
Release date:2016-07-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
5BMV
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-VINBLASTINE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta chain, Stathmin-4, ...
Authors:Wang, Y., Chen, Q., Zhang, R.
Deposit date:2015-05-23
Release date:2016-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules.
Mol.Pharmacol., 89, 2016
6J07
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CRYSTAL STRUCTURE OF HUMAN TERB2 AND TERB1
Descriptor:Telomere repeats-binding bouquet formation protein 2, Telomere repeats-binding bouquet formation protein 1, ZINC ION
Authors:Wang, Y., Chen, Y., Wu, J., Huang, C., Lei, M.
Deposit date:2018-12-21
Release date:2019-02-27
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
Nat Commun, 10, 2019
6J08
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CRYSTAL STRUCTURE OF HUMAN MAJIN AND TERB2
Descriptor:Membrane-anchored junction protein, Telomere repeats-binding bouquet formation protein 2
Authors:Wang, Y., Chen, Y., Wu, J., Huang, C., Lei, M.
Deposit date:2018-12-21
Release date:2019-02-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
Nat Commun, 10, 2019
3TDL
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STRUCTURE OF HUMAN SERUM ALBUMIN IN COMPLEX WITH DAUDA
Descriptor:Serum albumin, MYRISTIC ACID, 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid
Authors:Wang, Y., Luo, Z., Shi, X., Wang, H., Nie, L.
Deposit date:2011-08-11
Release date:2012-06-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin
Protein Sci., 20, 2011
5EX7
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CRYSTAL STRUCTURE OF BRAT NHL DOMAIN IN COMPLEX WITH AN 8-NT HUNCHBACK MRNA
Descriptor:Brain tumor protein, RNA (5'-R(P*UP*UP*UP*GP*UP*UP*GP*U)-3')
Authors:Wang, Y., Yu, Z., Wang, M., Liu, C.P., Yang, N., Xu, R.M.
Deposit date:2015-11-23
Release date:2015-12-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA
To Be Published
5IJB
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THE LIGAND-FREE STRUCTURE OF THE MOUSE TLR4/MD-2 COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
Authors:Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJC
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THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/NEOSEPTIN-3 COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
Authors:Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJD
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THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID A COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
Authors:Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5Y7L
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SOLUTION STRUCTURE OF HBETA4 EXTRACELLULAR LOOP OF BK POTASSIUM CHANNEL
Descriptor:Calcium-activated potassium channel subunit beta-4
Authors:Wang, Y., Lan, W., Ding, J., Cao, C.
Deposit date:2017-08-17
Release date:2018-08-01
Method:SOLUTION NMR
Cite:Solution structure of extracellular loop of human beta 4 subunit of BK channel and its biological implication on ChTX sensitivity.
Sci Rep, 8, 2018
3B44
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CRYSTAL STRUCTURE OF GLPG W136A MUTANT
Descriptor:glpG, B-NONYLGLUCOSIDE
Authors:Wang, Y., Maegawa, S., Akiyama, Y., Ha, Y.
Deposit date:2007-10-23
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
3B45
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CRYSTAL STRUCTURE OF GLPG AT 1.9A RESOLUTION
Descriptor:glpG, B-NONYLGLUCOSIDE
Authors:Wang, Y., Maegawa, S., Akiyama, Y., Ha, Y.
Deposit date:2007-10-23
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
4XT9
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RORGAMMA (263-509) COMPLEXED WITH GSK2435341A AND SRC2
Descriptor:Nuclear receptor ROR-gamma, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, N-[4-(2,5-dichlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, ...
Authors:Wang, Y., Ma, Y.
Deposit date:2015-01-23
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent ROR gamma t inverse agonists
Bioorg.Med.Chem., 23, 2015
5C8Y
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CRYSTAL STRUCTURE OF T2R-TTL-PLINABULIN COMPLEX
Descriptor:Tubulin alpha, Tubulin beta, Stathmin-4, ...
Authors:Wang, Y., Yu, Y., Chen, Q., Yang, J.
Deposit date:2015-06-26
Release date:2015-11-04
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
5CA0
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CRYSTAL STRUCTURE OF T2R-TTL-LEXIBULIN COMPLEX
Descriptor:Tubulin alpha-1B chain, Uncharacterized protein, Stathmin-4, ...
Authors:Wang, Y., Yu, Y., Chen, Q., Yang, J.
Deposit date:2015-06-29
Release date:2015-11-04
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
5CA1
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CRYSTAL STRUCTURE OF T2R-TTL-NOCODAZOLE COMPLEX
Descriptor:Tubulin alpha, Tubulin beta-2 chain, Stathmin-4, ...
Authors:Wang, Y., Yu, Y., Chen, Q., Yang, J.
Deposit date:2015-06-29
Release date:2015-11-04
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
5CB4
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CRYSTAL STRUCTURE OF T2R-TTL-TIVANTINIB COMPLEX
Descriptor:Tubulin alpha, Tubulin beta, Stathmin-4, ...
Authors:Wang, Y., Yu, Y., Chen, Q., Yang, J.
Deposit date:2015-06-30
Release date:2015-11-04
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.193 Å)
Cite:Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
5EZY
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CRYSTAL STRUCTURE OF T2R-TTL-TACCALONOLIDE AJ COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Wang, Y., Yu, Y., Chen, Q., Yang, J.
Deposit date:2015-11-27
Release date:2017-01-11
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Mechanism of microtubule stabilization by taccalonolide AJ
Nat Commun, 8, 2017
6O58
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HUMAN MCU-EMRE COMPLEX, DIMER OF CHANNEL
Descriptor:Calcium uniporter protein, mitochondrial, Essential MCU regulator, ...
Authors:Wang, Y., Bai, X., Jiang, Y.
Deposit date:2019-03-01
Release date:2019-05-22
Last modified:2019-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter.
Cell, 177, 2019