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4WV6
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BU of 4wv6 by Molmil
Heterodimer of Importin alpha 1 with nuclear localization signal of TAF8
Descriptor: 1,2-ETHANEDIOL, Importin subunit alpha-1, Transcription initiation factor TFIID subunit 8
Authors:Trowitzsch, S.
Deposit date:2014-11-04
Release date:2015-01-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.
Nat Commun, 6, 2015
4WV4
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BU of 4wv4 by Molmil
Heterodimer of TAF8/TAF10
Descriptor: CHLORIDE ION, GLYCEROL, Transcription initiation factor TFIID subunit 10, ...
Authors:Trowitzsch, S.
Deposit date:2014-11-04
Release date:2015-01-28
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.
Nat Commun, 6, 2015
3ELS
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BU of 3els by Molmil
Crystal Structure of Yeast Pml1p, Residues 51-204
Descriptor: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Trowitzsch, S, Weber, G, Luehrmann, R, Wahl, M.C.
Deposit date:2008-09-23
Release date:2009-02-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex.
J.Mol.Biol., 385, 2009
3ELV
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BU of 3elv by Molmil
Crystal Structure of Full-Length Yeast Pml1p
Descriptor: Pre-mRNA leakage protein 1, SULFATE ION
Authors:Trowitzsch, S, Weber, G, L hrmann, R, Wahl, M.C.
Deposit date:2008-09-23
Release date:2009-02-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex.
J.Mol.Biol., 385, 2009
6Z9U
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BU of 6z9u by Molmil
Crystal structure of a TSEN15-34 heterodimer.
Descriptor: GLYCEROL, tRNA-splicing endonuclease subunit Sen15, tRNA-splicing endonuclease subunit Sen34
Authors:Trowitzsch, S, Sekulovski, S.
Deposit date:2020-06-04
Release date:2021-06-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.10001779 Å)
Cite:Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia.
Nat Commun, 12, 2021
6ENY
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BU of 6eny by Molmil
Structure of the human PLC editing module
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ...
Authors:Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R.
Deposit date:2017-10-07
Release date:2017-11-29
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structure of the human MHC-I peptide-loading complex.
Nature, 551, 2017
2POX
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BU of 2pox by Molmil
Dark state structure of the reversibly switchable fluorescent protein Dronpa
Descriptor: Fluorescent protein Dronpa
Authors:Trowitzsch, S, Weber, G, Wahl, M.C.
Deposit date:2007-04-27
Release date:2007-07-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.946 Å)
Cite:Structural basis for reversible photoswitching in Dronpa
Proc.Natl.Acad.Sci.Usa, 104, 2007
7ZRZ
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BU of 7zrz by Molmil
Structure of the human tRNA splicing endonuclease defines substrate recognition
Descriptor: pre-tRNA Arg TCT 3-2, tRNA-splicing endonuclease subunit Sen15, tRNA-splicing endonuclease subunit Sen2, ...
Authors:Sekulovski, S, Trowitzsch, S.
Deposit date:2022-05-05
Release date:2023-05-17
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural basis of substrate recognition by human tRNA splicing endonuclease TSEN.
Nat.Struct.Mol.Biol., 30, 2023
8OMR
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BU of 8omr by Molmil
Human tRNA guanine transglycosylase (TGT) bound to tRNAAsp
Descriptor: 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase catalytic subunit 1, ...
Authors:Sievers, K, Neumann, P, Susac, L, Trowitzsch, S, Tampe, R, Ficner, R.
Deposit date:2023-03-31
Release date:2023-12-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and functional insights into tRNA recognition by human tRNA guanine transglycosylase.
Structure, 32, 2024
3LSA
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BU of 3lsa by Molmil
Padron0.9-OFF (non-fluorescent state)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ...
Authors:Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S.
Deposit date:2010-02-12
Release date:2010-03-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron.
J.Biol.Chem., 285, 2010
2IOV
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BU of 2iov by Molmil
Bright-state structure of the reversibly switchable fluorescent protein Dronpa
Descriptor: Fluorescent protein Dronpa
Authors:Stiel, A.C, Trowitzsch, S, Weber, G, Andresen, M, Eggeling, C, Hell, S.W, Jakobs, S, Wahl, M.C.
Deposit date:2006-10-11
Release date:2006-12-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:1.8 A bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants
Biochem.J., 402, 2007
7QNG
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BU of 7qng by Molmil
Structure of a MHC I-Tapasin-ERp57 complex
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
Authors:Mueller, I.K, Thomas, C, Trowitzsch, S, Tampe, R.
Deposit date:2021-12-20
Release date:2022-09-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity.
Nat Commun, 13, 2022
7QPD
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BU of 7qpd by Molmil
Structure of the human MHC I peptide-loading complex editing module
Descriptor: Beta-2-microglobulin, Calreticulin, HLA class I histocompatibility antigen, ...
Authors:Domnick, A, Susac, L, Trowitzsch, S, Thomas, C, Tampe, R.
Deposit date:2022-01-03
Release date:2022-07-20
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Molecular basis of MHC I quality control in the peptide loading complex.
Nat Commun, 13, 2022
5LL6
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BU of 5ll6 by Molmil
Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation initiation
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Heuer, A, Gerovac, M, Schmidt, C, Trowitzsch, S, Preis, A, Koetter, P, Berninghausen, O, Becker, T, Beckmann, R, Tampe, R.
Deposit date:2016-07-26
Release date:2017-04-12
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation.
Nat. Struct. Mol. Biol., 24, 2017
2MKC
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BU of 2mkc by Molmil
Cooperative Structure of the Heterotrimeric pre-mRNA Retention and Splicing Complex
Descriptor: Pre-mRNA leakage protein 1, Pre-mRNA-splicing factor CWC26, U2 snRNP component IST3
Authors:Wysoczanski, P, Schneider, C, Xiang, S, Munari, F, Trowitzsch, S, Wahl, M.C, Luhrmann, R, Becker, S, Zweckstetter, M.
Deposit date:2014-02-04
Release date:2014-09-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex.
Nat.Struct.Mol.Biol., 21, 2014
3LS3
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BU of 3ls3 by Molmil
Padron0.9-ON (fluorescent state)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ...
Authors:Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S.
Deposit date:2010-02-12
Release date:2010-03-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron.
J.Biol.Chem., 285, 2010
3PGW
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BU of 3pgw by Molmil
Crystal structure of human U1 snRNP
Descriptor: DNA 5'-D(*AP*GP*GP*TP*AP*AP*GP*TP*A)-3', Sm B, Sm G, ...
Authors:Weber, G, Trowitzsch, S, Kastner, B, Luehrmann, R, Wahl, M.C.
Deposit date:2010-11-02
Release date:2010-12-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Functional organization of the Sm core in the crystal structure of human U1 snRNP.
Embo J., 29, 2010
2A54
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BU of 2a54 by Molmil
fluorescent protein asFP595, A143S, on-state, 1min irradiation
Descriptor: CHLORIDE ION, GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2
Authors:Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S.
Deposit date:2005-06-30
Release date:2005-08-16
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and mechanism of the reversible photoswitch of a fluorescent protein
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A52
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BU of 2a52 by Molmil
fluorescent protein asFP595, S158V, on-state
Descriptor: GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2
Authors:Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S.
Deposit date:2005-06-30
Release date:2005-08-16
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and mechanism of the reversible photoswitch of a fluorescent protein
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A50
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BU of 2a50 by Molmil
fluorescent protein asFP595, wt, off-state
Descriptor: GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2
Authors:Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S.
Deposit date:2005-06-30
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure and mechanism of the reversible photoswitch of a fluorescent protein
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A56
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BU of 2a56 by Molmil
fluorescent protein asFP595, A143S, on-state, 5min irradiation
Descriptor: GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2
Authors:Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S.
Deposit date:2005-06-30
Release date:2005-08-16
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and mechanism of the reversible photoswitch of a fluorescent protein
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A53
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BU of 2a53 by Molmil
fluorescent protein asFP595, A143S, off-state
Descriptor: CHLORIDE ION, GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2
Authors:Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S.
Deposit date:2005-06-30
Release date:2005-08-16
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and mechanism of the reversible photoswitch of a fluorescent protein
Proc.Natl.Acad.Sci.Usa, 102, 2005
4PKD
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BU of 4pkd by Molmil
U1-70k in complex with U1 snRNA stem-loops 1 and U1-A RRM in complex with stem-loop 2
Descriptor: IMIDAZOLE, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A,U1 small nuclear ribonucleoprotein 70 kDa, ...
Authors:Oubridge, C, Kondo, Y, van Roon, A.M, Nagai, K.
Deposit date:2014-05-14
Release date:2014-12-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
Elife, 4, 2015

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