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8U1E
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BU of 8u1e by Molmil
Apo protein tyrosine phosphatase 1B (PTP1B) at high resolution (1.43 A) in space group P43212 with two distinctly ordered chains
Descriptor: MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1
Authors:Sharma, S, Mehlman, S.T, Keedy, A.D.
Deposit date:2023-08-31
Release date:2023-09-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:High-resolution double vision of the allosteric phosphatase PTP1B.
Acta Crystallogr.,Sect.F, 80, 2024
7MDY
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BU of 7mdy by Molmil
LolCDE nucleotide-bound
Descriptor: ADP ORTHOVANADATE, Lipo-releasing system transmembrane protein lolC, Lipoprotein transporter subunit LolE, ...
Authors:Sharma, S, Liao, M.
Deposit date:2021-04-06
Release date:2021-08-11
Last modified:2021-08-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
Nat Commun, 12, 2021
7MDX
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BU of 7mdx by Molmil
LolCDE nucleotide-free
Descriptor: Lipo-releasing system transmembrane protein lolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein, ...
Authors:Sharma, S, Liao, M.
Deposit date:2021-04-06
Release date:2021-08-11
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
Nat Commun, 12, 2021
7SHX
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BU of 7shx by Molmil
A functional SNP regulates E-cadherin expression by dynamically remodeling the 3D structure of a promoter-associated non-coding RNA transcript, NMR, minimized average structure
Descriptor: RNA (94-MER)
Authors:Sharma, S, Varani, G.
Deposit date:2021-10-11
Release date:2022-10-19
Last modified:2022-11-16
Method:SOLUTION NMR
Cite:A functional SNP regulates E-cadherin expression by dynamically remodeling the 3D structure of a promoter-associated non-coding RNA transcript.
Nucleic Acids Res., 50, 2022
1NKX
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BU of 1nkx by Molmil
CRYSTAL STRUCTURE OF A PROTEOLYTICALLY GENERATED FUNCTIONAL MONOFERRIC C-LOBE OF BOVINE LACTOFERRIN AT 1.9A RESOLUTION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
Authors:Sharma, S, Jasti, J, Kumar, J, Mohanty, A.K, Singh, T.P.
Deposit date:2003-01-06
Release date:2003-09-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of a Proteolytically Generated Functional Monoferric C-lobe of Bovine Lactoferrin at 1.9A Resolution
J.Mol.Biol., 331, 2003
6U79
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BU of 6u79 by Molmil
Solution NMR structure of 5' UTR stem loop B from West Nile Virus
Descriptor: 5' UTR region stem loop
Authors:Sharma, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-09-01
Release date:2020-08-26
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication.
Biochem.Biophys.Res.Commun., 531, 2020
6W3M
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BU of 6w3m by Molmil
Solution NMR Structure of 5'UTR Stem Loop B in DENV4 Flavivirus.
Descriptor: RNA (41-MER)
Authors:Sharma, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-03-09
Release date:2020-09-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication.
Biochem.Biophys.Res.Commun., 531, 2020
8FKJ
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BU of 8fkj by Molmil
Yeast ATP Synthase in conformation-3, at pH 6
Descriptor: ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ...
Authors:Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M.
Deposit date:2022-12-21
Release date:2024-01-24
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 2024
8FL8
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BU of 8fl8 by Molmil
Yeast ATP Synthase structure in presence of MgATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ...
Authors:Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M.
Deposit date:2022-12-21
Release date:2024-01-17
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 2024
8F29
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BU of 8f29 by Molmil
Yeast ATP synthase in conformation-1 at pH 6
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ...
Authors:Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M.
Deposit date:2022-11-07
Release date:2024-02-07
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 2024
8F39
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BU of 8f39 by Molmil
Yeast ATP synthase in conformation-2, at pH 6
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ...
Authors:Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M.
Deposit date:2022-11-09
Release date:2024-02-07
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 2024
2YIM
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BU of 2yim by Molmil
The enolisation chemistry of a thioester-dependent racemase: the 1.4 A crystal structure of a complex with a planar reaction intermediate analogue
Descriptor: 2-METHYLACETOACETYL COA, GLYCEROL, PHOSPHATE ION, ...
Authors:Sharma, S, Bhaumik, P, Venkatesan, R, Hiltunen, J.K, Conzelmann, E, Juffer, A.H, Wierenga, R.K.
Deposit date:2011-05-16
Release date:2012-03-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:The Enolization Chemistry of a Thioester-Dependent Racemase: The 1.4 A Crystal Structure of a Reaction Intermediate Complex Characterized by Detailed Qm/Mm Calculations.
J Phys Chem B, 116, 2012
2MDL
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BU of 2mdl by Molmil
Structure and NMR assignments of Scylla Serrata anti lipopolysaccharide Factor-24 (SsALF-24)
Descriptor: Anti-lipopolysaccharide factor
Authors:Sharma, S, Barnwal, R, Yedery, R, Reddy, K.
Deposit date:2013-09-11
Release date:2014-09-17
Method:SOLUTION NMR
Cite:NMR assignments of Scylla Serrata anti lipopolysaccharide Factor-24 (SsALF-24)
To be Published
8DU7
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BU of 8du7 by Molmil
Room-temperature serial synchrotron crystallography (SSX) structure of apo PTP1B
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
Authors:Ebrahim, A, Sharma, S, Keedy, D.A.
Deposit date:2022-07-27
Release date:2022-08-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Room-temperature serial synchrotron crystallography of the human phosphatase PTP1B.
Acta Crystallogr.,Sect.F, 79, 2023
6IF9
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BU of 6if9 by Molmil
Solution-state NMR structure of G57W human gammaS crystallin
Descriptor: Gamma-crystallin S
Authors:Sharma, S, Bari, K.J, Chary, K.V.R.
Deposit date:2018-09-19
Release date:2019-04-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of G57W mutant of human gamma S-crystallin and its involvement in cataract formation.
J. Struct. Biol., 205, 2019
1G2X
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BU of 1g2x by Molmil
Sequence induced trimerization of krait PLA2: crystal structure of the trimeric form of krait PLA2
Descriptor: PHOSPHOLIPASE A2
Authors:Singh, G, Gourinath, S, Sharma, S, Bhanumathi, S, Paramsivam, M, Singh, T.P.
Deposit date:2000-10-22
Release date:2003-06-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Sequence-induced trimerization of phospholipase A2: structure of a trimeric isoform of PLA2 from common krait (Bungarus caeruleus) at 2.5 A resolution.
Acta Crystallogr.,Sect.F, 61, 2005
1G0Z
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BU of 1g0z by Molmil
SPECIFIC MUTATIONS IN KRAIT PLA2 LEAD TO DIMERIZATION OF PROTEIN MOLECULES: CRYSTAL STRUCTURE OF KRAIT PLA2 AT 2.1 RESOLUTION
Descriptor: CHLORIDE ION, PHOSPHOLIPASE A2
Authors:Singh, T.P, Gourinath, S, Sharma, S, Singh, G.
Deposit date:2000-10-10
Release date:2003-06-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Specific mutations in Krait PLA2 lead to dimerization of protein molecules: Crystal structure of Krait PLA2 at 2.1 resolution.
To be Published
1LN8
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BU of 1ln8 by Molmil
Crystal Structure of a New Isoform of Phospholipase A2 from Naja naja sagittifera at 1.6 A Resolution
Descriptor: CALCIUM ION, PHOSPHATE ION, Phospholipase A2
Authors:Singh, R.K, Vikram, P, Paramasivam, M, Jabeen, T, Sharma, S, Kaur, P, Srinivasan, A, Singh, T.P.
Deposit date:2002-05-03
Release date:2003-05-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of a New Form of Phospholipase A2 from Naja naja sagittifera at 1.6 A Resolution
to be published
1MF4
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BU of 1mf4 by Molmil
Structure-based design of potent and selective inhibitors of phospholipase A2: Crystal structure of the complex formed between phosholipase A2 from Naja Naja sagittifera and a designed peptide inhibitor at 1.9 A resolution
Descriptor: CALCIUM ION, Phospholipase A2, VAL-ALA-PHE-ARG-SER
Authors:Singh, R.K, Vikram, P, Paramsivam, M, Jabeen, T, Sharma, S, Makker, J, Dey, S, Kaur, P, Srinivasan, A, Singh, T.P.
Deposit date:2002-08-09
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features
Biochemistry, 42, 2003
1LJY
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BU of 1ljy by Molmil
Crystal Structure of a Novel Regulatory 40 kDa Mammary Gland Protein (MGP-40) secreted during Involution
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MGP-40
Authors:Mohanty, A.K, Singh, G, Paramasivam, M, Saravanan, K, Jabeen, T, Sharma, S, Yadav, S, Kaur, P, Kumar, P, Srinivasan, A, Singh, T.P.
Deposit date:2002-04-23
Release date:2003-03-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of a Novel Regulatory 40 kDa Mammary Gland Protein (MGP-40) secreted during Involution
J.Biol.Chem., 278, 2003
5H7X
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BU of 5h7x by Molmil
Crystal structure of the complex of Phosphopantetheine adenylyltransferase from Acinetobacter baumannii with 2-hydroxy-1,2,3-propane tricarboxylate at 1.76 A resolution
Descriptor: CITRIC ACID, Phosphopantetheine adenylyltransferase
Authors:Singh, P.K, Gupta, A, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2016-11-21
Release date:2016-12-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural and binding studies of phosphopantetheine adenylyl transferase from Acinetobacter baumannii.
Biochim Biophys Acta Proteins Proteom, 1867, 2019
1F61
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BU of 1f61 by Molmil
CRYSTAL STRUCTURE OF ISOCITRATE LYASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor: ISOCITRATE LYASE, MAGNESIUM ION
Authors:Sharma, V, Sharma, S, Hoener zu Bentrup, K.H, McKinney, J.D, Russell, D.G, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2000-06-19
Release date:2000-08-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis.
Nat.Struct.Biol., 7, 2000
1F8I
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BU of 1f8i by Molmil
CRYSTAL STRUCTURE OF ISOCITRATE LYASE:NITROPROPIONATE:GLYOXYLATE COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor: GLYOXYLIC ACID, ISOCITRATE LYASE, MAGNESIUM ION, ...
Authors:Sharma, V, Sharma, S, Hoener zu Bentrup, K, McKinney, J.D, Russell, D.G, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2000-06-30
Release date:2000-12-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis.
Nat.Struct.Biol., 7, 2000
1F8M
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BU of 1f8m by Molmil
CRYSTAL STRUCTURE OF 3-BROMOPYRUVATE MODIFIED ISOCITRATE LYASE (ICL) FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor: ISOCITRATE LYASE, MAGNESIUM ION, PYRUVIC ACID
Authors:Sharma, V, Sharma, S, Hoener zu Bentrup, K, McKinney, J.D, Russell, D.G, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2000-06-30
Release date:2000-12-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis.
Nat.Struct.Biol., 7, 2000
4OUG
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BU of 4oug by Molmil
Crystal structure of the ternary complex of camel peptidoglycan recognition protein, PGRP-S with lipopolysaccharide and palmitic acid at 2.46 A resolution
Descriptor: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, GLYCEROL, L(+)-TARTARIC ACID, ...
Authors:Yamini, S, Sharma, P, Yadav, S.P, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2014-02-17
Release date:2014-03-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Crystal structure of the ternary complex of camel peptidoglycan recognition protein, PGRP-S with lipopolysaccharide and palmitic acid at 2.46 A resolution
To be Published

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