Author results

5C5A
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CRYSTAL STRUCTURE OF HDM2 IN COMPLEX WITH NUTLIN-3A
Descriptor:E3 ubiquitin-protein ligase Mdm2, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, SULFATE ION, ...
Authors:Orts, J., Waelti, M.A., Marsh, M., Vera, L., Gossert, A.D., Guentert, P., Riek, R.
Deposit date:2015-06-19
Release date:2016-06-29
Method:X-RAY DIFFRACTION (1.146 Å)
Cite:NMR Molecular Replacement, NMR2
To Be Published
4TLS
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN GLU92PRO MUTANT
Descriptor:Transthyretin, PHOSPHATE ION, GLYCEROL, ...
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4XFO
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STRUCTURE OF AN AMYLOID-FORMING SEGMENT TAVVTN FROM HUMAN TRANSTHYRETIN
Descriptor:Amyloid-forming peptide TAVVTN
Authors:Saelices, L., Sawaya, M., Cascio, D., Eisenberg, D.S.
Deposit date:2014-12-27
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL5
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN SER85PRO MUTANT
Descriptor:Transthyretin, SODIUM ION, CHLORIDE ION
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TLK
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN SER85PRO/GLU92PRO MUTANT
Descriptor:Transthyretin, SODIUM ION, GLYCEROL, ...
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4QXX
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE GNLVS (RESIDUES 26-30) FROM THE EOSINOPHIL MAJOR BASIC PROTEIN (EMBP)
Descriptor:Bone marrow proteoglycan
Authors:Soriaga, A.B., Soragni, A., Sawaya, M.R., Eisenberg, D.
Deposit date:2014-07-22
Release date:2015-03-18
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (1.445 Å)
Cite:Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation.
Mol.Cell, 57, 2015
6C3F
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AMYLOID FORMING PEPTIDE IYKVEI FROM TRANSTHYRETIN
Descriptor:ILE-TYR-LYS-VAL-GLU-ILE, trifluoroacetic acid
Authors:Saelices, L., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2018-01-09
Release date:2018-04-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
5HBP
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THE CRYSTAL OF RHODANESE DOMAIN OF YGAP TREATED WITH SNOC
Descriptor:Inner membrane protein YgaP
Authors:Eichmann, C., Tzitzilonis, C., Nakamura, T., Kwiatkowski, W., Maslennikov, I., Choe, S., Lipton, S.A., Riek, R.
Deposit date:2016-01-01
Release date:2016-08-10
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
4TNE
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN THR119TYR MUTANT
Descriptor:Transthyretin, GLYCEROL
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-06-03
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
6C3G
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AMYLOID FORMING PEPTIDE KALGIS FROM TRANSTHYRETIN
Descriptor:LYS-ALA-LEU-GLY-ILE-SER, SULFATE ION, GLYCEROL
Authors:Saelices, L., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2018-01-09
Release date:2018-04-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
5HBL
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NATIVE RHODANESE DOMAIN OF YGAP PREPARED WITH 1MM DDT IS S-NITROSYLATED
Descriptor:Inner membrane protein YgaP
Authors:Eichmann, C., Tzitzilonis, C., Nakamura, T., Kwiatkowski, W., Maslennikov, I., Choe, S., Lipton, S.A., Riek, R.
Deposit date:2015-12-31
Release date:2016-08-10
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.617 Å)
Cite:S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
5HBO
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NATIVE RHODANESE DOMAIN OF YGAP PREPARED WITHOUT DDT IS BOTH S-NITROSYLATED AND S-SULFHYDRATED
Descriptor:Inner membrane protein YgaP
Authors:Eichmann, C., Tzitzilonis, C., Nakamura, T., Kwiatkowski, W., Maslennikov, I., Choe, S., Lipton, S.A., Riek, R.
Deposit date:2016-01-01
Release date:2016-08-10
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
5HBQ
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C63D MUTANT OF THE RHODANESE DOMAIN OF YGAP
Descriptor:Inner membrane protein YgaP, CHLORIDE ION, SODIUM ION
Authors:Eichmann, C., Tzitzilonis, C., Nakamura, T., Kwiatkowski, W., Maslennikov, I., Choe, S., Lipton, S.A., Riek, R.
Deposit date:2016-01-02
Release date:2016-08-10
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
5HPA
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THE CRYSTAL OF RHODANESE DOMAIN OF YGAP TREATED WITH SODIUM THIOSULFATE
Descriptor:Inner membrane protein YgaP
Authors:Eichmann, C., Tzitzilonis, C., Kwiatkowski, W., Riek, R.
Deposit date:2016-01-20
Release date:2017-02-01
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:S-Sulfhydration of the Catalytic Cysteine in the Rhodanese Domain of YgaP is a Complex Dynamical Process.
To Be Published
4TLT
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN
Descriptor:Transthyretin, MAGNESIUM ION
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TM9
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN THR119TRP MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-31
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL4
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN VAL30MET MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
1Y6I
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SYNECHOCYSTIS GUN4
Descriptor:Mg-chelatase cofactor GUN4
Authors:Verdecia, M.A., Larkin, R.M., Ferrer, J.L., Riek, R., Chory, J., Noel, J.P.
Deposit date:2004-12-06
Release date:2005-05-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of the Mg-chelatase cofactor GUN4 reveals a novel hand-shaped fold for porphyrin binding
Plos Biol., 3, 2005
4TKW
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN LEU55PRO MUTANT
Descriptor:Transthyretin
Authors:Saelices, L., Cascio, D., Sawaya, M., Eisenberg, D.S.
Deposit date:2014-05-27
Release date:2015-10-21
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4XFN
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STRUCTURE OF AN AMYLOID FORMING PEPTIDE AEVVFT FROM HUMAN TRANSTHYRETIN
Descriptor:Amyloid forming peptide AEVVFT
Authors:Saelices, L., Sawaya, M., Cascio, D., Eisenberg, D.S.
Deposit date:2014-12-27
Release date:2015-10-21
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
6C88
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE VAVHVF FROM TRANSTHYRETIN
Descriptor:VAL-ALA-VAL-HIS-VAL-PHE, GLYCEROL
Authors:Saelices, L., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2018-01-24
Release date:2018-04-18
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
4H88
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STRUCTURE OF POM1 FAB FRAGMENT COMPLEXED WITH MOUSE PRPC FRAGMENT 120-230
Descriptor:Major prion protein, POM1 FAB CHAIN H, POM1 FAB CHAIN L, ...
Authors:Baral, P.K., Wieland, B., Swayampakula, M., James, M.N.
Deposit date:2012-09-21
Release date:2013-07-31
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Nature, 501, 2013
2WVQ
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STRUCTURE OF THE HET-S N-TERMINAL DOMAIN. MUTANT D23A, P33H
Descriptor:SMALL S PROTEIN, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL
Authors:Greenwald, J., Buhtz, C., Ritter, C., Kwiatkowski, W., Choe, S., Saupe, S.J., Riek, R.
Deposit date:2009-10-19
Release date:2010-07-28
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The mechanism of prion inhibition by HET-S.
Mol. Cell, 38, 2010
2WVO
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STRUCTURE OF THE HET-S N-TERMINAL DOMAIN
Descriptor:SMALL S PROTEIN, CHLORIDE ION
Authors:Greenwald, J., Buhtz, C., Ritter, C., Kwiatkowski, W., Choe, S., Saupe, S.J., Riek, R.
Deposit date:2009-10-19
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Mechanism of Prion Inhibition by Het-S.
Mol.Cell, 38, 2010
2WVN
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STRUCTURE OF THE HET-S N-TERMINAL DOMAIN
Descriptor:SMALL S PROTEIN
Authors:Greenwald, J., Buhtz, C., Ritter, C., Kwiatkowski, W., Choe, S., Saupe, S.J., Riek, R.
Deposit date:2009-10-19
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:The Mechanism of Prion Inhibition by Het-S.
Mol.Cell, 38, 2010