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1T8B
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BU of 1t8b by Molmil
Crystal structure of refolded PHOU-like protein (gi 2983430) from Aquifex aeolicus
Descriptor: Phosphate transport system protein phoU homolog
Authors:Oganesyan, V, Kim, S.-H, Oganesyan, N, Jancarik, J, Adams, P.D, Kim, R, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-05-11
Release date:2004-12-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Crystal structure of the "PhoU-like" phosphate uptake regulator from Aquifex aeolicus.
J.Bacteriol., 187, 2005
1T72
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BU of 1t72 by Molmil
Crystal structure of phosphate transport system protein phoU from Aquifex aeolicus
Descriptor: Phosphate transport system protein phoU homolog
Authors:Oganesyan, V, Kim, S.-H, Oganesyan, N, Jancarik, J, Adams, P.D, Kim, R, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-05-07
Release date:2004-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the "PhoU-like" phosphate uptake regulator from Aquifex aeolicus.
J.Bacteriol., 187, 2005
4YPG
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BU of 4ypg by Molmil
Structural Insights Into the Neutralization Properties of a Human Anti-Interferon Monoclonal Antibody
Descriptor: Interferon alpha-2, NICKEL (II) ION, Sifalimumab heavy chain, ...
Authors:Oganesyan, V, Dall'Acqua, W.F.
Deposit date:2015-03-12
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab.
J.Biol.Chem., 290, 2015
4N0F
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BU of 4n0f by Molmil
Human FcRn complexed with human serum albumin
Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Serum albumin
Authors:Oganesyan, V, Wu, H, Dall'Acqua, W.F.
Deposit date:2013-10-01
Release date:2014-02-05
Last modified:2014-04-09
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms.
J.Biol.Chem., 289, 2014
4N0U
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BU of 4n0u by Molmil
Ternary complex between Neonatal Fc receptor, serum albumin and Fc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Ig gamma-1 chain C region, ...
Authors:Oganesyan, V, Wu, H, Dall'Acqua, W.F.
Deposit date:2013-10-02
Release date:2014-02-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms.
J.Biol.Chem., 289, 2014
2HEK
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BU of 2hek by Molmil
Crystal structure of O67745, a hypothetical protein from Aquifex aeolicus at 2.0 A resolution.
Descriptor: BROMIDE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Oganesyan, V, Jancarik, J, Adams, P.D, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-06-21
Release date:2006-07-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structure of O67745_AQUAE, a hypothetical protein from Aquifex aeolicus.
Acta Crystallogr.,Sect.F, 63, 2007
1OZ9
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BU of 1oz9 by Molmil
Crystal structure of AQ_1354, a hypothetical protein from Aquifex aeolicus
Descriptor: Hypothetical protein AQ_1354
Authors:Oganesyan, V, Busso, D, Brandsen, J, Chen, S, Jancarik, J, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2003-04-08
Release date:2003-09-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.894 Å)
Cite:Structure of the hypothetical protein AQ_1354 from Aquifex aeolicus.
Acta Crystallogr.,Sect.D, 59, 2003
1LQV
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BU of 1lqv by Molmil
Crystal structure of the Endothelial protein C receptor with phospholipid in the groove in complex with Gla domain of protein C.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Endothelial protein C receptor, ...
Authors:Oganesyan, V, Oganesyan, N, Terzyan, S, Dongfeng, Q, Dauter, Z, Esmon, N.L, Esmon, C.T.
Deposit date:2002-05-13
Release date:2002-06-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of the endothelial protein C receptor and a bound phospholipid.
J.Biol.Chem., 277, 2002
1L8J
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BU of 1l8j by Molmil
Crystal Structure of the Endothelial Protein C Receptor and Bound Phospholipid Molecule
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, ...
Authors:Oganesyan, V, Oganesyan, N, Terzyan, S, Dongfeng, Q, Dauter, Z, Esmon, N.L, Esmon, C.T.
Deposit date:2002-03-20
Release date:2002-06-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the endothelial protein C receptor and a bound phospholipid.
J.Biol.Chem., 277, 2002
1S7O
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BU of 1s7o by Molmil
Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes
Descriptor: Hypothetical UPF0122 protein SPy1201/SpyM3_0842/SPs1042/spyM18_1152
Authors:Oganesyan, V, Pufan, R, DeGiovanni, A, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-01-29
Release date:2004-06-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structure of the putative DNA-binding protein SP_1288 from Streptococcus pyogenes.
Acta Crystallogr.,Sect.D, 60, 2004
3C2S
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BU of 3c2s by Molmil
Structural Characterization of a Human Fc Fragment Engineered for Lack of Effector Functions
Descriptor: IGHM protein, ZINC ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Oganesyan, V, Wu, H, Dall'Acqua, W.F.
Deposit date:2008-01-25
Release date:2008-08-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural characterization of a human Fc fragment engineered for lack of effector functions.
Acta Crystallogr.,Sect.D, 64, 2008
2QL1
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BU of 2ql1 by Molmil
Structural Characterization of a Mutated, ADCC-Enhanced Human Fc Fragment
Descriptor: IGHM protein, ZINC ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Oganesyan, V, Wu, H, Dall'Acqua, W.F.
Deposit date:2007-07-12
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.534 Å)
Cite:Structural characterization of a mutated, ADCC-enhanced human Fc fragment
Mol.Immunol., 45, 2008
3FJT
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BU of 3fjt by Molmil
Crystal structure of a human Fc fragment engineered for extended serum half-life
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
Authors:Oganesyan, V, Wu, H, Dall'Acqua, W.F.
Deposit date:2008-12-15
Release date:2009-03-24
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterization of a human Fc fragment engineered for extended serum half-life.
Mol.Immunol., 46, 2009
1T75
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BU of 1t75 by Molmil
Crystal structure of Escherichia coli beta carbonic anhydrase
Descriptor: Protein yadF, ZINC ION
Authors:Oganesyan, V, Kim, S.-H, Kim, R, Jancarik, J, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-05-07
Release date:2004-06-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Escherichia coli beta carbonic anhydrase
TO BE PUBLISHED
1EUE
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BU of 1eue by Molmil
RAT OUTER MITOCHONDRIAL MEMBRANE CYTOCHROME B5
Descriptor: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Oganesyan, V, Zhang, X.
Deposit date:2000-04-19
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modulation of redox potential in electron transfer proteins: effects of complex formation on the active site microenvironment of cytochrome b5.
FARADAY DISC.CHEM.SOC, 116, 2001
6BRB
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BU of 6brb by Molmil
Novel non-antibody protein scaffold targeting CD40L
Descriptor: CD40 ligand, Tn3-like, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Oganesyan, V, Baca, M, Thisted, T, Grinberg, L, Wu, H, Dall'Acqua, W.F.
Deposit date:2017-11-30
Release date:2018-12-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity.
Sci Transl Med, 11, 2019
6CYF
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BU of 6cyf by Molmil
PcrV fragment with bound Fab
Descriptor: IgG1 antibody, heavy chain fragment, kappa light chain, ...
Authors:Oganesyan, V.
Deposit date:2018-04-05
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates.
J. Infect. Dis., 218, 2018
7R8U
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BU of 7r8u by Molmil
LOX-1 - Structural and Functional Studies of a Receptor Implicated in Atherosclerosis
Descriptor: Antibody light chain, kappa, Antigen binding fragment, ...
Authors:Oganesyan, V, van Dyk, N.
Deposit date:2021-06-27
Release date:2022-06-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structural and functional studies of a monoclonal antibody blocking LOX-1
Commun Med, 2023
3CFW
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BU of 3cfw by Molmil
L-selectin lectin and EGF domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, L-selectin, ...
Authors:Mehta, P, Oganesyan, V, Terzyan, S, Mather, T, McEver, R.P.
Deposit date:2008-03-04
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.
J.Biol.Chem., 292, 2017
6ATT
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BU of 6att by Molmil
39S Fab bound to HER2 ecd
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 39S Fab heavy chain, ...
Authors:Oganesyan, V.Y, Dall'Acqua, W.F.
Deposit date:2017-08-29
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.77 Å)
Cite:Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody.
J. Biol. Chem., 293, 2018
4ZNE
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BU of 4zne by Molmil
IgG1 Fc-FcgammaRI ecd complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Oganesyan, V.Y, Dall'Acqua, W.F.
Deposit date:2015-05-04
Release date:2015-11-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural insights into the interaction of human IgG1 with Fc gamma RI: no direct role of glycans in binding.
Acta Crystallogr.,Sect.D, 71, 2015
4U6V
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BU of 4u6v by Molmil
Mechanisms of Neutralization of a Human Anti-Alpha Toxin Antibody
Descriptor: Alpha-hemolysin, Fab, antigen binding fragment, ...
Authors:Oganesyan, V.Y, Peng, L, Damschroder, M.M, Cheng, L, Sadowska, A, Tkaczyk, C, Sellman, B, Wu, H, Dall'Acqua, W.F.
Deposit date:2014-07-29
Release date:2014-09-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Mechanisms of Neutralization of a Human Anti-alpha-toxin Antibody.
J.Biol.Chem., 289, 2014
6BWV
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BU of 6bwv by Molmil
Crystal Structure of the 4-1BB/4-1BBL Complex
Descriptor: DI(HYDROXYETHYL)ETHER, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9
Authors:Oganesyan, V, Gilbreth, R.N, Baca, M.
Deposit date:2017-12-15
Release date:2018-05-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human 4-1BB/4-1BBL complex.
J. Biol. Chem., 293, 2018
1YT5
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BU of 1yt5 by Molmil
Crystal structure of NAD kinase from Thermotoga maritima
Descriptor: SULFATE ION, inorganic polyphosphate/ATP-NAD kinase
Authors:Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-02-09
Release date:2005-04-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a NAD kinase from Thermotoga maritima at 2.3 A resolution.
Acta Crystallogr.,Sect.F, 61, 2005
1JFD
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BU of 1jfd by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE
Descriptor: INORGANIC PYROPHOSPHATASE, SULFATE ION
Authors:Oganesyan, V, Avaeva, S.M, Huber, R, Harutyunyan, E.H.
Deposit date:1997-05-31
Release date:1997-12-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Escherichia coli inorganic pyrophosphatase complexed with SO4(2-). Ligand-induced molecular asymmetry.
FEBS Lett., 410, 1997

 

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