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3RC0
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BU of 3rc0 by Molmil
Human SETD6 in complex with RelA Lys310 peptide
Descriptor: 1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ...
Authors:Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X.
Deposit date:2011-03-30
Release date:2011-05-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.
Nucleic Acids Res., 39, 2011
7CRQ
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BU of 7crq by Molmil
NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (2:1 binding mode)
Descriptor: DNA (168-MER), Histone H2A, Histone H2B, ...
Authors:Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z.
Deposit date:2020-08-14
Release date:2020-10-21
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature, 590, 2021
7CRP
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BU of 7crp by Molmil
NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (1:1 binding mode)
Descriptor: DNA (168-MER), Histone H2A, Histone H2B, ...
Authors:Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z.
Deposit date:2020-08-14
Release date:2020-10-21
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature, 590, 2021
7CRO
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BU of 7cro by Molmil
NSD2 bearing E1099K/T1150A dual mutation in complex with 187-bp NCP
Descriptor: DNA (168-MER), Histone H2A, Histone H2B, ...
Authors:Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z.
Deposit date:2020-08-14
Release date:2020-10-21
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature, 590, 2021
7CRR
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BU of 7crr by Molmil
Native NSD3 bound to 187-bp nucleosome
Descriptor: DNA (168-MER), DNA(168-MER), Histone H2A, ...
Authors:Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z.
Deposit date:2020-08-14
Release date:2020-10-21
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature, 590, 2021
3MDF
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BU of 3mdf by Molmil
Crystal structure of the RRM domain of Cyclophilin 33
Descriptor: Peptidyl-prolyl cis-trans isomerase E
Authors:Hom, R.A, Chang, P.Y, Roy, S, Mussleman, C.A, Glass, K.C, Seleznevia, A.I, Gozani, O, Ismagilov, R.F, Cleary, M.L, Kutateladze, T.G.
Deposit date:2010-03-30
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain.
J.Mol.Biol., 400, 2010
3OQ5
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BU of 3oq5 by Molmil
Crystal structure of the 3-MBT domain from human L3MBTL1 in complex with p53K382me1
Descriptor: Cellular tumor antigen p53, Lethal(3)malignant brain tumor-like protein
Authors:Roy, S, West, L.E, Weiner, K.L, Hayashi, R, Shi, X, Appella, E, Gozani, O, Kutateladze, T.
Deposit date:2010-09-02
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5005 Å)
Cite:The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression.
J.Biol.Chem., 285, 2010
3QXY
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BU of 3qxy by Molmil
Human SETD6 in complex with RelA Lys310
Descriptor: 1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ...
Authors:Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X.
Deposit date:2011-03-02
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.
Nucleic Acids Res., 39, 2011
8FZB
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BU of 8fzb by Molmil
Crystal structure of human FAM86A
Descriptor: Protein-lysine N-methyltransferase EEF2KMT, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Shao, Z, Lu, J, Song, J.
Deposit date:2023-01-28
Release date:2023-06-21
Last modified:2023-06-28
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:The FAM86 domain of FAM86A confers substrate specificity to promote EEF2-Lys525 methylation.
J.Biol.Chem., 299, 2023
6OX0
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BU of 6ox0 by Molmil
SETD3 in Complex with an Actin Peptide with Sinefungin Replacing SAH as Cofactor
Descriptor: 1,2-ETHANEDIOL, Actin Peptide, Histone-lysine N-methyltransferase setd3, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.755 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
5HH7
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BU of 5hh7 by Molmil
crystal structure of Arabidopsis ORC1b BAH-PHD cassette in complex with unmodified H3 peptide
Descriptor: Histone H3 1-15 peptide, Origin of replication complex subunit 1B, ZINC ION
Authors:Li, S, Du, J.
Deposit date:2016-01-10
Release date:2016-03-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structural Basis for the Unique Multivalent Readout of Unmodified H3 Tail by Arabidopsis ORC1b BAH-PHD Cassette
Structure, 24, 2016
2PNX
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BU of 2pnx by Molmil
The PHD finger of ING4 in complex with an H3K4Me3 histone peptide
Descriptor: H3K4Me3 peptide, Inhibitor of growth protein 4, ZINC ION
Authors:Champagne, K.S, Johnson, K, Kutateladze, T.G.
Deposit date:2007-04-25
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation
Mol.Cell, 33, 2009
3LH0
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BU of 3lh0 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2
Descriptor: DIMETHYLATED p53 LYSINE 372 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Roy, S, Kutateladze, T.G.
Deposit date:2010-01-21
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
6V62
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BU of 6v62 by Molmil
SETD3 double mutant (N255F/W273A) in Complex with an Actin Peptide with His73 Replaced with Lysine
Descriptor: 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ...
Authors:Dai, S, Horton, J.R, Cheng, X.
Deposit date:2019-12-04
Release date:2020-01-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
6V63
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BU of 6v63 by Molmil
SETD3 WT in Complex with an Actin Peptide with His73 Replaced with Glutamine
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Actin, ...
Authors:Dai, S, Horton, J.R, Cheng, X.
Deposit date:2019-12-04
Release date:2020-01-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
6OX3
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BU of 6ox3 by Molmil
SETD3 in Complex with an Actin Peptide with His73 Replaced with Lysine
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.785 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6OX4
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BU of 6ox4 by Molmil
A SETD3 Mutant (N255A) in Complex with an Actin Peptide
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6OX1
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BU of 6ox1 by Molmil
SETD3 in Complex with an Actin Peptide with Target Histidine Partially Methylated
Descriptor: 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6OX5
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BU of 6ox5 by Molmil
A SETD3 Mutant (N255A) in Complex with an Actin Peptide with His73 Replaced with Lysine
Descriptor: 1,2-ETHANEDIOL, Actin Peptide, Actin-histidine N-methyltransferase, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.098 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
6OX2
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BU of 6ox2 by Molmil
SETD3in Complex with an Actin Peptide with the Target Histidine Fully Methylated
Descriptor: 1,2-ETHANEDIOL, Actin Peptide, GLYCEROL, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.089 Å)
Cite:Structural basis for the target specificity of actin histidine methyltransferase SETD3.
Nat Commun, 10, 2019
7LMM
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BU of 7lmm by Molmil
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2
Descriptor: DNA (cytosine-5)-methyltransferase 1,DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION
Authors:Ren, W, Song, J.
Deposit date:2021-02-05
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Nat Commun, 12, 2021
7LMK
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BU of 7lmk by Molmil
Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3
Descriptor: DNA (cytosine-5)-methyltransferase 1, Histone H4, ZINC ION
Authors:Ren, W, Song, J.
Deposit date:2021-02-05
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.647 Å)
Cite:DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Nat Commun, 12, 2021
7LMS
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BU of 7lms by Molmil
Structure of human SetD3 methyl-transferase in complex with 2A protease from Coxsackievirus B3
Descriptor: Actin-histidine N-methyltransferase, Protease 2A, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Verba, K.A, Schulze-Gahmen, U.
Deposit date:2021-02-05
Release date:2022-08-10
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3.
Nat Commun, 13, 2022
2V83
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BU of 2v83 by Molmil
Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide
Descriptor: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
Authors:Ramon-Maiques, S, Yang, W.
Deposit date:2007-08-02
Release date:2007-12-11
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V88
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BU of 2v88 by Molmil
Crystal structure of RAG2-PHD finger in complex with H3R2me2sK4me2 peptide
Descriptor: H3R2ME2SK4ME3 PEPTIDE, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
Authors:Ramon-Maiques, S, Yang, W.
Deposit date:2007-08-03
Release date:2007-12-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007

 

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