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1A0L
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BU of 1a0l by Molmil
HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE
Descriptor: (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid, BETA-TRYPTASE
Authors:Pereira, P.J.B, Bergner, A, Macedo-Ribeiro, S, Huber, R, Matschiner, G, Fritz, H, Sommerhoff, C.P, Bode, W.
Deposit date:1997-12-03
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.
Nature, 392, 1998
1BX7
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BU of 1bx7 by Molmil
HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.2 ANGSTROMS
Descriptor: HIRUSTASIN, SULFATE ION
Authors:Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E.
Deposit date:1998-10-14
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
1LDT
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BU of 1ldt by Molmil
COMPLEX OF LEECH-DERIVED TRYPTASE INHIBITOR WITH PORCINE TRYPSIN
Descriptor: CALCIUM ION, TRYPSIN, TRYPTASE INHIBITOR
Authors:Stubbs, M.T.
Deposit date:1997-05-15
Release date:1998-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition.
J.Biol.Chem., 272, 1997
1HIA
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BU of 1hia by Molmil
KALLIKREIN COMPLEXED WITH HIRUSTASIN
Descriptor: HIRUSTASIN, KALLIKREIN
Authors:Mittl, P, Di Marco, S, Gruetter, M.
Deposit date:1996-12-12
Release date:1997-12-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A new structural class of serine protease inhibitors revealed by the structure of the hirustasin-kallikrein complex.
Structure, 5, 1997
1CSE
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BU of 1cse by Molmil
THE HIGH-RESOLUTION X-RAY CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN SUBTILISIN CARLSBERG AND EGLIN C, AN ELASTASE INHIBITOR FROM THE LEECH HIRUDO MEDICINALIS. STRUCTURAL ANALYSIS, SUBTILISIN STRUCTURE AND INTERFACE GEOMETRY
Descriptor: CALCIUM ION, EGLIN C, SUBTILISIN CARLSBERG
Authors:Bode, W.
Deposit date:1988-06-03
Release date:1988-07-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The high-resolution X-ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis. Structural analysis, subtilisin structure and interface geometry.
Eur.J.Biochem., 166, 1987
1AN1
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BU of 1an1 by Molmil
LEECH-DERIVED TRYPTASE INHIBITOR/TRYPSIN COMPLEX
Descriptor: CALCIUM ION, TRYPSIN, TRYPTASE INHIBITOR
Authors:Priestle, J.P, Di Marco, S.
Deposit date:1997-06-26
Release date:1998-07-01
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
Structure, 5, 1997
1BX8
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BU of 1bx8 by Molmil
HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.4 ANGSTROMS
Descriptor: HIRUSTASIN, SULFATE ION
Authors:Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E.
Deposit date:1998-10-14
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
1C9P
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BU of 1c9p by Molmil
COMPLEX OF BDELLASTASIN WITH PORCINE TRYPSIN
Descriptor: BDELLASTASIN, CALCIUM ION, TRYPSIN
Authors:Rester, U.
Deposit date:1999-08-03
Release date:2000-08-03
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system.
J.Mol.Biol., 293, 1999
1TFX
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BU of 1tfx by Molmil
COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN
Descriptor: CALCIUM ION, TISSUE FACTOR PATHWAY INHIBITOR, TRYPSIN
Authors:Stubbs, M.T, Huber, R.
Deposit date:1997-01-21
Release date:1998-01-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa.
J.Mol.Biol., 269, 1997
1SBN
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BU of 1sbn by Molmil
REFINED CRYSTAL STRUCTURES OF SUBTILISIN NOVO IN COMPLEX WITH WILD-TYPE AND TWO MUTANT EGLINS. COMPARISON WITH OTHER SERINE PROTEINASE INHIBITOR COMPLEXES
Descriptor: CALCIUM ION, EGLIN C, SUBTILISIN NOVO BPN'
Authors:Gruetter, M.G, Heinz, D.W, Priestle, J.P.
Deposit date:1991-12-20
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined crystal structures of subtilisin novo in complex with wild-type and two mutant eglins. Comparison with other serine proteinase inhibitor complexes.
J.Mol.Biol., 217, 1991
1SIB
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BU of 1sib by Molmil
REFINED CRYSTAL STRUCTURES OF SUBTILISIN NOVO IN COMPLEX WITH WILD-TYPE AND TWO MUTANT EGLINS. COMPARISON WITH OTHER SERINE PROTEINASE INHIBITOR COMPLEXES
Descriptor: CALCIUM ION, EGLIN C, SUBTILISIN NOVO BPN'
Authors:Gruetter, M.G, Heinz, D.W, Priestle, J.P.
Deposit date:1993-08-02
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Refined crystal structures of subtilisin novo in complex with wild-type and two mutant eglins. Comparison with other serine proteinase inhibitor complexes.
J.Mol.Biol., 217, 1991
1EJA
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BU of 1eja by Molmil
STRUCTURE OF PORCINE TRYPSIN COMPLEXED WITH BDELLASTASIN, AN ANTISTASIN-TYPE INHIBITOR
Descriptor: BDELLASTASIN, SODIUM ION, TRYPSIN
Authors:Rester, U, Moser, M, Huber, R, Bode, W.
Deposit date:2000-03-02
Release date:2001-03-02
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:L-Isoaspartate 115 of porcine beta-trypsin promotes crystallization of its complex with bdellastasin.
Acta Crystallogr.,Sect.D, 56, 2000

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