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3N4I
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CRYSTAL STRUCTURE OF THE SHV-1 D104E BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX
Descriptor:Beta-lactamase SHV-1, Beta-lactamase inhibitory protein
Authors:Hanes, M.S., Reynolds, K.A., McNamara, C., Ghosh, P., Bonomo, R.A., Kirsch, J.F., Handel, T.M.
Deposit date:2010-05-21
Release date:2011-03-09
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Specificity and Cooperativity at beta-lactamase Position 104 in TEM-1/BLIP and SHV-1/BLIP interactions
Proteins, 79, 2011
3FSL
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CRYSTAL STRUCTURE OF TYROSINE AMINOTRANSFERASE TRIPPLE MUTANT (P181Q,R183G,A321K) FROM ESCHERICHIA COLI AT 2.35 A RESOLUTION
Descriptor:Aromatic-amino-acid aminotransferase, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE
Authors:Malashkevich, V.N., Ng, B., Kirsch, J.F.
Deposit date:2009-01-09
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of tyrosine aminotransferase tripple mutant (P181Q,R183G,A321K) from Escherichia coli at 2.35 A resolution
To be Published
3E2L
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CRYSTAL STRUCTURE OF THE KPC-2 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP)
Descriptor:Carbapenemase, Beta-lactamase inhibitory protein
Authors:Hanes, M.S., Jude, K.M., Berger, J.M., Kirsch, J.F., Bonomo, R.A., Handel, T.M.
Deposit date:2008-08-05
Release date:2009-08-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein
Biochemistry, 48, 2009
3C4O
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CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) E73M/S130K/S146M COMPLEX
Descriptor:Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION
Authors:Reynolds, K.A., Hanes, M.S., Thomson, J.M., Antczak, A.J., Berger, J.M., Bonomo, R.A., Kirsch, J.F., Handel, T.M.
Deposit date:2008-01-30
Release date:2008-05-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
3C4P
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CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) E73M COMPLEX
Descriptor:Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION
Authors:Reynolds, K.A., Hanes, M.S., Thomson, J.M., Antczak, A.J., Berger, J.M., Bonomo, R.A., Kirsch, J.F., Handel, T.M.
Deposit date:2008-01-30
Release date:2008-05-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
2G2U
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CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX
Descriptor:Beta-lactamase SHV-1, Beta-lactamase inhibitory protein
Authors:Reynolds, K.A., Thomson, J.M., Corbett, K.D., Bethel, C.R., Berger, J.M., Kirsch, J.F., Bonomo, R.A., Handel, T.M.
Deposit date:2006-02-16
Release date:2006-07-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
2G2W
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CRYSTAL STRUCTURE OF THE SHV D104K BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX
Descriptor:Beta-lactamase SHV-1, Beta-lactamase inhibitory protein
Authors:Reynolds, K.A., Thomson, J.M., Corbett, K.D., Bethel, C.R., Berger, J.M., Kirsch, J.F., Bonomo, R.A., Handel, T.M.
Deposit date:2006-02-16
Release date:2006-07-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
1YNU
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CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH L-VINYLGLYCINE
Descriptor:1-aminocyclopropane-1-carboxylate synthase, NICKEL (II) ION, POTASSIUM ION, ...
Authors:Capitani, G., Tschopp, M., Eliot, A.C., Kirsch, J.F., Grutter, M.G.
Deposit date:2005-01-25
Release date:2005-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of ACC synthase inactivated by the mechanism-based inhibitor L-vinylglycine.
Febs Lett., 579, 2005
1TOE
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UNLIGANDED STRUCTURE OF HEXAMUTANT + A293D MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor:Aspartate aminotransferase, SULFATE ION
Authors:Chow, M.A., McElroy, K.E., Corbett, K.D., Berger, J.M., Kirsch, J.F.
Deposit date:2004-06-14
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
1TOG
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HYDROCINNAMIC ACID-BOUND STRUCTURE OF SRHEPT + A293D MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor:Aspartate aminotransferase, HYDROCINNAMIC ACID
Authors:Chow, M.A., McElroy, K.E., Corbett, K.D., Berger, J.M., Kirsch, J.F.
Deposit date:2004-06-14
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
1TOI
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HYDROCINNAMIC ACID-BOUND STRUCTURE OF HEXAMUTANT + A293D MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor:Aspartate aminotransferase, HYDROCINNAMIC ACID
Authors:Chow, M.A., McElroy, K.E., Corbett, K.D., Berger, J.M., Kirsch, J.F.
Deposit date:2004-06-14
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
1TOJ
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HYDROCINNAMIC ACID-BOUND STRUCTURE OF SRHEPT MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor:Aspartate aminotransferase, HYDROCINNAMIC ACID
Authors:Chow, M.A., McElroy, K.E., Corbett, K.D., Berger, J.M., Kirsch, J.F.
Deposit date:2004-06-14
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
1TOK
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MALEIC ACID-BOUND STRUCTURE OF SRHEPT MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor:Aspartate aminotransferase, MALEIC ACID
Authors:Chow, M.A., McElroy, K.E., Corbett, K.D., Berger, J.M., Kirsch, J.F.
Deposit date:2004-06-14
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
1S06
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CRYSTAL STRUCTURE OF THE R253K MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE
Descriptor:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION
Authors:Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F.
Deposit date:2003-12-30
Release date:2004-03-23
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
1S07
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CRYSTAL STRUCTURE OF THE R253A MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE
Descriptor:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F.
Deposit date:2003-12-30
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
1S08
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CRYSTAL STRUCTURE OF THE D147N MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE
Descriptor:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION
Authors:Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F.
Deposit date:2003-12-30
Release date:2004-03-23
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
1S09
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CRYSTAL STRUCTURE OF THE Y144F MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE
Descriptor:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION
Authors:Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F.
Deposit date:2003-12-30
Release date:2004-03-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
1S0A
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CRYSTAL STRUCTURE OF THE Y17F MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE
Descriptor:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION
Authors:Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F.
Deposit date:2003-12-30
Release date:2004-03-23
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
1MGV
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CRYSTAL STRUCTURE OF THE R391A MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE
Descriptor:7,8-diamino-pelargonic acid aminotransferase, SODIUM ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Eliot, A.C., Sandmark, J., Schneider, G., Kirsch, J.F.
Deposit date:2002-08-16
Release date:2002-11-27
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Dual-Specific Active Site of 7,8-Diaminopelargonic Acid Synthase and the Effect of the R391A Mutation
Biochemistry, 41, 2002
1M7Y
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CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH L-AMINOETHOXYVINYLGLYCINE
Descriptor:1-aminocyclopropane-1-carboxylate synthase, (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, (4R)-2-METHYLPENTANE-2,4-DIOL
Authors:Capitani, G., McCarthy, D., Gut, H., Gruetter, M.G., Kirsch, J.F.
Deposit date:2002-07-23
Release date:2002-12-23
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Apple 1-Aminocyclopropane-1-carboxylate Synthase in Complex with the Inhibitor L-Aminoethoxyvinylglycine
J.Biol.Chem., 277, 2002
1M4N
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CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH [2-(AMINO-OXY)ETHYL](5'-DEOXYADENOSIN-5'-YL)(METHYL)SULFONIUM
Descriptor:1-aminocyclopropane-1-carboxylate synthase, PYRIDOXAL-5'-PHOSPHATE, (2-AMINOOXY-ETHYL)-[5-(6-AMINO-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDRO-FURAN-2-YLMETHYL]-METHYL-SULFONIUM, ...
Authors:Capitani, G., Eliot, A.C., Gut, H., Khomutov, R.M., Kirsch, J.F., Grutter, M.G.
Deposit date:2002-07-03
Release date:2003-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structure of 1-aminocyclopropane-1-carboxylate synthase in complex with an amino-oxy analogue of the substrate: implications for substrate binding.
BIOCHEM.BIOPHYS.ACTA PROTEINS & PROTEOMICS, 1647, 2003
1H6M
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COVALENT GLYCOSYL-ENZYME INTERMEDIATE OF HEN EGG WHITE LYSOZYME
Descriptor:LYSOZYME C, SODIUM ION, 2-deoxy-2-fluoro-alpha-D-glucopyranose, ...
Authors:Vocadlo, D.J., Davies, G.J., Laine, R., Withers, S.G.
Deposit date:2001-06-19
Release date:2001-08-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Catalysis by Hen Egg-White Lysozyme Proceeds Via a Covalent Intermediate
Nature, 412, 2001
1B8G
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1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE
Descriptor:PROTEIN (1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE), PYRIDOXAL-5'-PHOSPHATE
Authors:Capitani, G., Hohenester, E., Feng, L., Storici, P., Kirsch, J.F., Jansonius, J.N.
Deposit date:1999-01-31
Release date:2000-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene.
J.Mol.Biol., 294, 1999
1AHE
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ASPARTATE AMINOTRANSFERASE HEXAMUTANT
Descriptor:ASPARTATE AMINOTRANSFERASE, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Malashkevich, V.N., Jansonius, J.N.
Deposit date:1995-02-22
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Alternating arginine-modulated substrate specificity in an engineered tyrosine aminotransferase.
Nat.Struct.Biol., 2, 1995
1AHF
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ASPARTATE AMINOTRANSFERASE HEXAMUTANT
Descriptor:ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, INDOLYLPROPIONIC ACID, ...
Authors:Malashkevich, V.N., Jansonius, J.N.
Deposit date:1995-02-22
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Alternating arginine-modulated substrate specificity in an engineered tyrosine aminotransferase.
Nat.Struct.Biol., 2, 1995
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