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4A3N
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CRYSTAL STRUCTURE OF HMG-BOX OF HUMAN SOX17
Descriptor:TRANSCRIPTION FACTOR SOX-17, ZINC ION
Authors:Gao, N., Gao, H., Qian, H., Si, S., Xie, Y.
Deposit date:2011-10-01
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Human Transcription Factor Sry-Related Box 17 Binding to DNA.
Protein Pept.Lett., 20, 2013
2RDO
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50S SUBUNIT WITH EF-G(GDPNP) AND RRF BOUND
Descriptor:5S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 50S ribosomal protein L25, ...
Authors:Gao, N., Zavialov, A.V., Ehrenberg, M., Frank, J.
Deposit date:2007-09-24
Release date:2008-03-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.
J.Mol.Biol., 374, 2007
1ZN1
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COORDINATES OF RRF FITTED INTO CRYO-EM MAP OF THE 70S POST-TERMINATION COMPLEX
Descriptor:ribosomal 23S RNA, ribosomal 16S RNA, Ribosome recycling factor, ...
Authors:Gao, N., Zavialov, A.V., Li, W., Sengupta, J., Valle, M., Gursky, R.P., Ehrenberg, M., Frank, J.
Deposit date:2005-05-11
Release date:2005-06-14
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies.
Mol.Cell, 18, 2005
1ZN0
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COORDINATES OF RRF AND EF-G FITTED INTO CRYO-EM MAP OF THE 50S SUBUNIT BOUND WITH BOTH EF-G (GDPNP) AND RRF
Descriptor:16S RIBOSOMAL RNA, Ribosome recycling factor, ELONGATION FACTOR G
Authors:Gao, N., Zavialov, A.V., Li, W., Sengupta, J., Valle, M., Gursky, R.P., Ehrenberg, M., Frank, J.
Deposit date:2005-05-11
Release date:2005-06-14
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (15.5 Å)
Cite:Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies.
Mol.Cell, 18, 2005
3J3R
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
Descriptor:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2014-10-22
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
3J3S
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
Descriptor:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2015-01-21
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3T
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
Descriptor:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2015-01-21
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3U
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
Descriptor:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2015-01-21
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3V
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ATOMIC MODEL OF THE IMMATURE 50S SUBUNIT FROM BACILLUS SUBTILIS (STATE I-A)
Descriptor:50S ribosomal protein L32, 50S ribosomal protein L34, 50S ribosomal protein L1, ...
Authors:Li, N., Guo, Q., Zhang, Y., Yuan, Y., Ma, C., Lei, J., Gao, N.
Deposit date:2013-04-28
Release date:2013-06-12
Last modified:2013-08-28
Method:ELECTRON MICROSCOPY (13.3 Å)
Cite:Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013
3J3W
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ATOMIC MODEL OF THE IMMATURE 50S SUBUNIT FROM BACILLUS SUBTILIS (STATE II-A)
Descriptor:ribosome RNA 23S, 50S ribosomal protein L32, 50S ribosomal protein L2, ...
Authors:Li, N., Guo, Q., Zhang, Y., Yuan, Y., Ma, C., Lei, J., Gao, N.
Deposit date:2013-04-28
Release date:2013-06-12
Last modified:2013-08-28
Method:ELECTRON MICROSCOPY (10.7 Å)
Cite:Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013
3J8G
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF ENGA BOUND WITH THE 50S RIBOSOMAL SUBUNIT
Descriptor:5S rRNA, 23S rRNA, 50S ribosomal protein L28, ...
Authors:Zhang, X., Yan, K., Zhang, Y., Li, N., Ma, C., Li, Z., Zhang, Y., Feng, B., Liu, J., Sun, Y., Xu, Y., Lei, J., Gao, N.
Deposit date:2014-10-24
Release date:2014-11-26
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
3JA8
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CRYO-EM STRUCTURE OF THE MCM2-7 DOUBLE HEXAMER
Descriptor:Minichromosome Maintenance 2, Minichromosome Maintenance 3, Minichromosome Maintenance 4, ...
Authors:Li, N., Zhai, Y., Zhang, Y., Li, W., Yang, M., Lei, J., Tye, B.K., Gao, N.
Deposit date:2015-05-09
Release date:2015-08-05
Last modified:2015-08-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the eukaryotic MCM complex at 3.8 angstrom
Nature, 524, 2015
3JAC
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CRYO-EM STUDY OF A CHANNEL
Descriptor:Piezo-type mechanosensitive ion channel component 1
Authors:Ge, J., Li, W., Zhao, Q., Li, N., Xiao, B., Gao, N., Yang, M.
Deposit date:2015-06-05
Release date:2015-09-23
Last modified:2015-11-25
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Architecture of the mammalian mechanosensitive Piezo1 channel
Nature, 527, 2015
4CSU
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CRYO-EM STRUCTURES OF THE 50S RIBOSOME SUBUNIT BOUND WITH OBGE
Descriptor:50S RIBOSOMAL PROTEIN L28, 50S RIBOSOMAL PROTEIN L29, 50S RIBOSOMAL PROTEIN L30, ...
Authors:Feng, B., Mandava, C.S., Guo, Q., Wang, J., Cao, W., Li, N., Zhang, Y., Zhang, Y., Wang, Z., Wu, J., Sanyal, S., Lei, J., Gao, N.
Deposit date:2014-03-10
Release date:2014-06-04
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Plos Biol., 12, 2014
4FN7
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APO STRUCTURE OF THE MTB ENOYOL COA ISOMERASE (RV0632C)
Descriptor:Enoyl-CoA hydratase/isomerase family protein, CHLORIDE ION
Authors:Bruning, J.B., Gao, N., Hernandez, E.D., Li, H., Dang, N., Hung, L.W., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2012-06-19
Release date:2013-05-29
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:"Crystal Structure and Mechanism of the Prokaryotic Enoyl-CoA Isomerase (ECI)"
To be Published
4FN8
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CRYSTAL STRUCTURE OF THE MTB ENOYL COA ISOMERASE (RV0632C)IN COMPLEX WITH ACETOACETYL COA
Descriptor:Enoyl-CoA hydratase/isomerase family protein, ACETOACETYL-COENZYME A, SULFATE ION
Authors:Bruning, J.B., Gao, N., Hernandez, E.D., Li, H., Dang, N., Hung, L.W., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2012-06-19
Release date:2013-05-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.831 Å)
Cite:Crystal structure and mechanism of the prokaryotic enoyl CoA isomerase (ECI)
To be Published
4FNB
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CRYSTAL STRUCTURE OF THE MTB ENOYL COA ISOMERASE (RV0632C) IN COMPLEX WITH HYDROXYBUTYRL COA
Descriptor:Enoyl-CoA hydratase/isomerase family protein, SULFATE ION, 3-HYDROXYBUTANOYL-COENZYME A
Authors:Bruning, J.B., Gao, N., Hernandez, E.D., Li, H., Dang, N., Hung, L.W., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2012-06-19
Release date:2013-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure and Mechanism of the Prokaryotic Enoyl CoA Isomerase
To be Published
4FND
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CRYSTAL STRUCTURE OF THE MTB ENOYL COA ISOMERASE IN COMPLEX WITH HYDROXYHEXANOYL COA
Descriptor:Enoyl-CoA hydratase/isomerase family protein, (S)-3-Hydroxyhexanoyl-CoA, SULFATE ION
Authors:Bruning, J.B., Gao, N., Hernandez, E.D., Li, H., Dang, N., Hung, L.W., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2012-06-19
Release date:2013-05-29
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure and mechanism of the prokaryotic enoyl CoA isomerase
To be Published
5ADY
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CRYO-EM STRUCTURES OF THE 50S RIBOSOME SUBUNIT BOUND WITH HFLX
Descriptor:50S RIBOSOMAL PROTEIN L32, 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, ...
Authors:Zhang, Y., Mandava, C.S., Cao, W., Li, X., Zhang, D., Li, N., Zhang, Y., Zhang, X., Qin, Y., Mi, K., Lei, J., Sanyal, S., Gao, N.
Deposit date:2015-08-25
Release date:2015-10-14
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
5H4P
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STRUCTURAL SNAPSHOT OF CYTOPLASMIC PRE-60S RIBOSOMAL PARTICLES BOUND WITH NMD3, LSG1, TIF6 AND REH1
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Ma, C., Wu, S., Li, N., Chen, Y., Yan, K., Li, Z., Zheng, L., Lei, J., Woolford, J.L., Gao, N.
Deposit date:2016-11-01
Release date:2017-01-25
Last modified:2017-06-14
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1
Nat. Struct. Mol. Biol., 24, 2017
5H5U
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MECHANISTIC INSIGHTS INTO THE ALTERNATIVE TRANSLATION TERMINATION BY ARFA AND RF2
Descriptor:30S ribosomal protein S20, 30S ribosomal protein S21, Alternative ribosome-rescue factor A, ...
Authors:Ma, C., Kurita, D., Li, N., Chen, Y., Himeno, H., Gao, N.
Deposit date:2016-11-09
Release date:2017-01-25
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanistic insights into the alternative translation termination by ArfA and RF2
Nature, 541, 2017
5H7I
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CRYO-EM STRUCTURE OF THE CDT1-MCM2-7 COMPLEX IN AMPPNP STATE
Descriptor:DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ...
Authors:Zhai, Y., Cheng, E., Wu, H., Li, N., Yung, P.Y., Gao, N., Tye, B.K.
Deposit date:2016-11-18
Release date:2017-02-08
Last modified:2017-03-15
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer
Nat. Struct. Mol. Biol., 24, 2017
5WUA
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STRUCTURE OF A PANCREATIC ATP-SENSITIVE POTASSIUM CHANNEL
Descriptor:ATP-sensitive inward rectifier potassium channel 11,superfolder GFP, SUR1
Authors:Li, N., Wu, J.-X., Chen, L., Gao, N.
Deposit date:2016-12-16
Release date:2017-01-25
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structure of a Pancreatic ATP-Sensitive Potassium Channel
Cell, 168, 2017
5XF8
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CRYO-EM STRUCTURE OF THE CDT1-MCM2-7 COMPLEX IN AMPPNP STATE
Descriptor:DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ...
Authors:Zhai, Y., Cheng, E., Wu, H., Li, N., Yung, P.Y., Gao, N., Tye, B.K.
Deposit date:2017-04-09
Release date:2017-05-03
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer
Nat. Struct. Mol. Biol., 24, 2017
5ZQZ
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STRUCTURE OF HUMAN MITOCHONDRIAL TRIFUNCTIONAL PROTEIN, TETRAMER
Descriptor:Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta
Authors:Liang, K., Li, N., Dai, J., Wang, X., Liu, P., Chen, X., Wang, C., Gao, N., Xiao, J.
Deposit date:2018-04-20
Release date:2018-06-20
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of human mitochondrial trifunctional protein
Proc. Natl. Acad. Sci. U.S.A., 115, 2018