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2E56
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CRYSTAL STRUCTURE OF HUMAN MD-2
Descriptor:Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, MYRISTIC ACID
Authors:Ohto, U., Satow, Y.
Deposit date:2006-12-19
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa.
Science, 316, 2007
2E59
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CRYSTAL STRUCTURE OF HUMAN MD-2 IN COMPLEX WITH LIPID IVA
Descriptor:Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, ...
Authors:Ohto, U., Satow, Y.
Deposit date:2006-12-19
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa
Science, 316, 2007
2Z64
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CRYSTAL STRUCTURE OF MOUSE TLR4 AND MOUSE MD-2 COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Lee, J.-O., Kim, H.M., Park, B.S.
Deposit date:2007-07-22
Release date:2007-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
2Z65
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CRYSTAL STRUCTURE OF THE HUMAN TLR4 TV3 HYBRID-MD-2-ERITORAN COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B, Lymphocyte antigen 96, ...
Authors:Lee, J.-O., Kim, H.M., Park, B.S.
Deposit date:2007-07-22
Release date:2007-09-18
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
Cell(Cambridge,Mass.), 130, 2007
3FXI
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CRYSTAL STRUCTURE OF THE HUMAN TLR4-HUMAN MD-2-E.COLI LPS RA COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96, 2-amino-2-deoxy-alpha-D-glucopyranose, ...
Authors:Park, B.S., Song, D.H., Kim, H.M., Lee, J.-O.
Deposit date:2009-01-21
Release date:2009-03-03
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
Nature, 458, 2009
3ULA
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CRYSTAL STRUCTURE OF THE TV3 MUTANT F63W-MD-2-ERITORAN COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B, Lymphocyte antigen 96, ...
Authors:Kim, H.J., Cheong, H.K., Jeon, Y.H.
Deposit date:2011-11-10
Release date:2012-04-04
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein.
Plos One, 7, 2012
3VQ1
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CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID IVA COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2012-03-17
Release date:2012-05-09
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
Proc.Natl.Acad.Sci.USA, 109, 2012
3VQ2
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CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LPS COMPLEX
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2012-03-17
Release date:2012-05-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
Proc.Natl.Acad.Sci.USA, 109, 2012
4G8A
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CRYSTAL STRUCTURE OF HUMAN TLR4 POLYMORPHIC VARIANT D299G AND T399I IN COMPLEX WITH MD-2 AND LPS
Descriptor:Toll-like receptor 4, Lymphocyte antigen 96, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ohto, U., Shimizu, T.
Deposit date:2012-07-23
Release date:2012-10-17
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analyses of human Toll-like receptor 4 polymorphisms D299G and T399I
J.Biol.Chem., 287, 2012
5IJB
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THE LIGAND-FREE STRUCTURE OF THE MOUSE TLR4/MD-2 COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
Authors:Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJC
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THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/NEOSEPTIN-3 COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
Authors:Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJD
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THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID A COMPLEX
Descriptor:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
Authors:Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
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