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1AUK
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HUMAN ARYLSULFATASE A
Descriptor:ARYLSULFATASE A, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Lukatela, G., Krauss, N., Theis, K., Gieselmann, V., Von Figura, K., Saenger, W.
Deposit date:1997-08-29
Release date:1998-03-04
Last modified:2012-01-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis.
Biochemistry, 37, 1998
1E1Z
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CRYSTAL STRUCTURE OF AN ARYLSULFATASE A MUTANT C69S
Descriptor:Arylsulfatase A, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION
Authors:von Buelow, R., Schmidt, B., Dierks, T., von Figura, K., Uson, I.
Deposit date:2000-05-12
Release date:2001-05-10
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis.
J. Mol. Biol., 305, 2001
1E2S
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CRYSTAL STRUCTURE OF AN ARYLSULFATASE A MUTANT C69A
Descriptor:Arylsulfatase A, MAGNESIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:von Buelow, R., Schmidt, B., Dierks, T., von Figura, K., Uson, I.
Deposit date:2000-05-24
Release date:2000-12-06
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis.
J. Mol. Biol., 305, 2001
1E33
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CRYSTAL STRUCTURE OF AN ARYLSULFATASE A MUTANT P426L
Descriptor:Arylsulfatase A, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION
Authors:von Buelow, R., Schmidt, B., Dierks, T., von Figura, K., Uson, I.
Deposit date:2000-06-06
Release date:2001-05-25
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Defective oligomerization of arylsulfatase a as a cause of its instability in lysosomes and metachromatic leukodystrophy.
J. Biol. Chem., 277, 2002
1E3C
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CRYSTAL STRUCTURE OF AN ARYLSULFATASE A MUTANT C69S SOAKED IN SYNTHETIC SUBSTRATE
Descriptor:Arylsulfatase A, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION
Authors:von Buelow, R., Schmidt, B., Dierks, T., von Figura, K., Uson, I.
Deposit date:2000-06-13
Release date:2001-03-05
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis.
J. Mol. Biol., 305, 2001
1N2K
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CRYSTAL STRUCTURE OF A COVALENT INTERMEDIATE OF ENDOGENOUS HUMAN ARYLSULFATASE A
Descriptor:ARYLSULFATASE A, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Chruszcz, M., Laidler, P., Monkiewicz, M., Ortlund, E., Lebioda, L., Lewinski, K.
Deposit date:2002-10-23
Release date:2003-12-23
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of a covalent intermediate of endogenous human arylsulfatase A.
J.Inorg.Biochem., 96, 2003
1N2L
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CRYSTAL STRUCTURE OF A COVALENT INTERMEDIATE OF ENDOGENOUS HUMAN ARYLSULFATASE A
Descriptor:ARYLSULFATASE A, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Chruszcz, M., Laidler, P., Monkiewicz, M., Ortlund, E., Lebioda, L., Lewinski, K.
Deposit date:2002-10-23
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a covalent intermediate of endogenous human arylsulfatase A.
J.Inorg.Biochem., 96, 2003
2AIJ
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FORMYLGLYCINE GENERATING ENZYME C336S MUTANT COVALENTLY BOUND TO SUBSTRATE PEPTIDE CTPSR
Descriptor:Sulfatase modifying factor 1, CTPSR peptide from Arylsulfatase A, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Roeser, D., Rudolph, M.G.
Deposit date:2005-07-29
Release date:2005-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
Proc.Natl.Acad.Sci.Usa, 103, 2006
2AIK
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FORMYLGLYCINE GENERATING ENZYME C336S MUTANT COVALENTLY BOUND TO SUBSTRATE PEPTIDE LCTPSRA
Descriptor:Sulfatase modifying factor 1, LCTPSRA peptide from Arylsulfatase A, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Roeser, D., Rudolph, M.G.
Deposit date:2005-07-29
Release date:2005-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HI8
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HUMAN FORMYLGLYCINE GENERATING ENZYME, C336S MUTANT, BROMIDE CO-CRYSTALLIZATION
Descriptor:Sulfatase-modifying factor 1, CTPSR, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Rudolph, M.G., Roeser, D.
Deposit date:2006-06-29
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Probing the oxygen-binding site of the human formylglycine-generating enzyme using halide ions.
Acta Crystallogr.,Sect.D, 63, 2007
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