1JM7 | SOLUTION STRUCTURE OF THE BRCA1/BARD1 RING-DOMAIN HETERODIMER | Descriptor: | BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1, ZINC ION | Authors: | Brzovic, P.S., Rajagopal, P., Hoyt, D.W., King, M.-C., Klevit, R.E. | Deposit date: | 2001-07-17 | Release date: | 2001-10-03 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat.Struct.Biol., 8, 2001
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1JNX | |
1N5O | |
1OQA | SOLUTION STRUCTURE OF THE BRCT-C DOMAIN FROM HUMAN BRCA1 | Descriptor: | Breast cancer type 1 susceptibility protein | Authors: | Gaiser, O.J., Ball, L.J., Schmieder, P., Leitner, D., Strauss, H., Wahl, M., Kuhne, R., Oschkinat, H., Heinemann, U. | Deposit date: | 2003-03-07 | Release date: | 2004-06-15 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1. Biochemistry, 43, 2004
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1T15 | CRYSTAL STRUCTURE OF THE BRCA1 BRCT DOMAINS IN COMPLEX WITH THE PHOSPHORYLATED INTERACTING REGION FROM BACH1 HELICASE | Descriptor: | Breast cancer type 1 susceptibility protein, BRCA1 interacting protein C-terminal helicase 1 | Authors: | Clapperton, J.A., Manke, I.A., Lowery, D.M., Ho, T., Haire, L.F., Yaffe, M.B., Smerdon, S.J. | Deposit date: | 2004-04-15 | Release date: | 2004-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer Nat.Struct.Mol.Biol., 11, 2004
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1T29 | CRYSTAL STRUCTURE OF THE BRCA1 BRCT REPEATS BOUND TO A PHOSPHORYLATED BACH1 PEPTIDE | Descriptor: | Breast cancer type 1 susceptibility protein, BACH1 phosphorylated peptide | Authors: | Shiozaki, E.N., Gu, L., Yan, N., Shi, Y. | Deposit date: | 2004-04-20 | Release date: | 2004-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling. Mol.Cell, 14, 2004
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1T2U | STRUCTURAL BASIS OF PHOSPHOPEPTIDE RECOGNITION BY THE BRCT DOMAIN OF BRCA1: STRUCTURE OF BRCA1 MISSENSE VARIANT V1809F | Descriptor: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION | Authors: | Williams, R.S., Lee, M.S., Duong, D.D., Glover, J.N.M. | Deposit date: | 2004-04-22 | Release date: | 2004-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1 Nat.Struct.Mol.Biol., 11, 2004
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1T2V | STRUCTURAL BASIS OF PHOSPHO-PEPTIDE RECOGNITION BY THE BRCT DOMAIN OF BRCA1, STRUCTURE WITH PHOSPHOPEPTIDE | Descriptor: | Breast cancer type 1 susceptibility protein, BRCTide-7PS | Authors: | Williams, R.S., Lee, M.S., Hau, D.D., Glover, J.N.M. | Deposit date: | 2004-04-22 | Release date: | 2004-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1 Nat.Struct.Mol.Biol., 11, 2004
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1Y98 | STRUCTURE OF THE BRCT REPEATS OF BRCA1 BOUND TO A CTIP PHOSPHOPEPTIDE. | Descriptor: | Breast cancer type 1 susceptibility protein, CtIP PHOSPHORYLATED PEPTIDE, COBALT (II) ION, ... | Authors: | Varma, A.K., Brown, R.S., Birrane, G., Ladias, J.A.A. | Deposit date: | 2004-12-14 | Release date: | 2005-08-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex. Biochemistry, 44, 2005
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2ING | X-RAY STRUCTURE OF THE BRCA1 BRCT MUTANT M1775K | Descriptor: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION | Authors: | Birrane, G., Soni, A., Ladias, J.A.A. | Deposit date: | 2006-10-07 | Release date: | 2007-09-04 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach. Eur.J.Hum.Genet., 16, 2008
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3COJ | |
3K0H | THE CRYSTAL STRUCTURE OF BRCA1 BRCT IN COMPLEX WITH A MINIMAL RECOGNITION TETRAPEPTIDE WITH AN AMIDATED C-TERMINUS | Descriptor: | Breast cancer type 1 susceptibility protein, phospho peptide, NICKEL (II) ION, ... | Authors: | Campbell, S.J., Edwards, R.A., Glover, J.N. | Deposit date: | 2009-09-24 | Release date: | 2010-03-02 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1 Structure, 18, 2010
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3K0K | CRYSTAL STRUCTURE OF BRCA1 BRCT IN COMPLEX WITH A MINIMAL RECOGNITION TETRAPEPTIDE WITH A FREE CARBOXY C-TERMINUS. | Descriptor: | Breast cancer type 1 susceptibility protein, phospho peptide pSPTF-COOH, NICKEL (II) ION, ... | Authors: | Campbell, S.J., Edwards, R.A., Glover, J.N. | Deposit date: | 2009-09-24 | Release date: | 2010-03-02 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1 Structure, 18, 2010
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3K15 | CRYSTAL STRUCTURE OF BRCA1 BRCT D1840T IN COMPLEX WITH A MINIMAL RECOGNITION TETRAPEPTIDE WITH AN AMIDATED C-TERMINUS | Descriptor: | Breast cancer type 1 susceptibility protein, phospho peptide, NICKEL (II) ION, ... | Authors: | Campbell, S.J., Edwards, R.A., Glover, J.N. | Deposit date: | 2009-09-25 | Release date: | 2010-03-02 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1 Structure, 18, 2010
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3K16 | CRYSTAL STRUCTURE OF BRCA1 BRCT D1840T IN COMPLEX WITH A MINIMAL RECOGNITION TETRAPEPTIDE WITH A FREE CARBOXY C-TERMINUS | Descriptor: | Breast cancer type 1 susceptibility protein, phospho peptide, NICKEL (II) ION, ... | Authors: | Campbell, S.J., Edwards, R.A., Glover, J.N. | Deposit date: | 2009-09-25 | Release date: | 2010-03-02 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1 Structure, 18, 2010
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3PXA | |
3PXB | |
3PXC | |
3PXD | |
3PXE | |
4IFI | |
4IGK | |
4JLU | |
4OFB | |
4U4A | |