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1CDW
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HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA
Descriptor:DNA (5'-D(*CP*TP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*CP*TP*G)-3'), DNA (5'-D(*CP*AP*GP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*AP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP))
Authors:Nikolov, D.B., Chen, H., Halay, E.D., Hoffmann, A., Roeder, R.G., Burley, S.K.
Deposit date:1996-04-11
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a human TATA box-binding protein/TATA element complex.
Proc.Natl.Acad.Sci.USA, 93, 1996
1NVP
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HUMAN TFIIA/TBP/DNA COMPLEX
Descriptor:5'-D(*GP*GP*GP*GP*GP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*G)-3', 5'-D(*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*CP*CP*CP*CP*C)-3', TATA box binding protein, ...
Authors:Bleichenbacher, M., Tan, S., Richmond, T.J.
Deposit date:2003-02-04
Release date:2003-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel interactions between the components of human and yeast TFIIA/TBP/DNA complexes.
J.Mol.Biol., 332, 2003
1TGH
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TATA BINDING PROTEIN (TBP)/DNA COMPLEX
Descriptor:DNA (5'-D(*CP*GP*TP*AP*TP*AP*TP*AP*TP*AP*CP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP))
Authors:Juo, Z.S., Dickerson, R.E.
Deposit date:1996-02-13
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:How proteins recognize the TATA box.
J.Mol.Biol., 261, 1996
5FUR
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STRUCTURE OF HUMAN TFIID-IIA BOUND TO CORE PROMOTER DNA
Descriptor:TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2, ...
Authors:Louder, R.K., He, Y., Lopez-Blanco, J.R., Fang, J., Chacon, P., Nogales, E.
Deposit date:2016-01-29
Release date:2016-04-06
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly.
Nature, 531, 2016
1C9B
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CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
Descriptor:ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
Authors:Tsai, F.T.F., Sigler, P.B.
Deposit date:1999-08-01
Release date:2000-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
1JFI
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CRYSTAL STRUCTURE OF THE NC2-TBP-DNA TERNARY COMPLEX
Descriptor:5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*C)-3', 5'-D(*G*GP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*AP*A)-3', Transcription Regulator NC2 alpha chain, ...
Authors:Kamada, K., Shu, F., Chen, H., Malik, S., Stelzer, G., Roeder, R.G., Meisterernst, M., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-06-20
Release date:2001-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex.
Cell(Cambridge,Mass.), 106, 2001
4ROC
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HUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO U6#2 PROMOTER
Descriptor:Transcription factor IIIB 50 kDa subunit, TATA-box-binding protein, Template strand, ...
Authors:Vannini, A., Gouge, J., Satia, K., Guthertz, N.
Deposit date:2014-10-28
Release date:2015-12-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
Cell(Cambridge,Mass.), 163, 2015
4ROD
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HUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO TRNAU1 PROMOTER
Descriptor:Transcription factor IIIB 50 kDa subunit, TATA-box-binding protein, Template strand, ...
Authors:Vannini, A., Gouge, J., Satia, K., Guthertz, N.
Deposit date:2014-10-28
Release date:2015-12-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
Cell(Cambridge,Mass.), 163, 2015
4ROE
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HUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO RPPH1 PROMOTER
Descriptor:Transcription factor IIIB 50 kDa subunit, TATA-box-binding protein, Template strand, ...
Authors:Vannini, A., Gouge, J., Satia, K., Guthertz, N.
Deposit date:2014-10-28
Release date:2015-12-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
Cell(Cambridge,Mass.), 163, 2015
5IY6
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HUMAN HOLO-PIC IN THE CLOSED STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5IY7
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HUMAN HOLO-PIC IN THE OPEN STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5IY8
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HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5IY9
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HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS)
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5IYA
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HUMAN CORE-PIC IN THE CLOSED STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5IYB
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HUMAN CORE-PIC IN THE OPEN STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5IYC
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HUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5IYD
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HUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS)
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5N9G
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TFIIIB -TBP/BRF2/DNA AND SANT DOMAIN OF BDP1-
Descriptor:Transcription factor IIIB 50 kDa subunit, TATA-box-binding protein, Transcription factor TFIIIB component B'' homolog, ...
Authors:Gouge, J., Vannini, A., Guthertz, N.
Deposit date:2017-02-24
Release date:2017-06-14
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation.
Nat Commun, 8, 2017
6MZD
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HUMAN TFIID LOBE A CANONICAL
Descriptor:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 3, Transcription initiation factor TFIID subunit 4, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZL
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HUMAN TFIID CANONICAL STATE
Descriptor:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 3, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZM
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HUMAN TFIID BOUND TO PROMOTER DNA AND TFIIA
Descriptor:Transcription initiation factor TFIID subunit 1, TAF1, Transcription initiation factor TFIID subunit 2, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
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