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5WDJ
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CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH COMPOUND-6 AKA 7-(BENZYLOXY)-1H-[1,2, 3]TRIAZOLO[4,5-D]PYRIMIDIN-5-AMINE
Descriptor:Myeloperoxidase, 7-(benzyloxy)-1H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine, CHLORIDE ION, ...
Authors:Khan, J.A.
Deposit date:2017-07-05
Release date:2018-04-18
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Triazolopyrimidines identified as reversible myeloperoxidase inhibitors.
Medchemcomm, 8, 2017
6AZP
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A STRUCTURALLY DYNAMIC N-TERMINAL REGION DRIVES FUNCTION OF THE STAPHYLOCOCCAL PEROXIDASE INHIBITOR (SPIN)
Descriptor:Myeloperoxidase, Staphylococcal Peroxidase Inhibitor, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ramyar, K.X., Geisbrecht, B.V.
Deposit date:2017-09-11
Release date:2017-12-27
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.291 Å)
Cite:A structurally dynamic N-terminal region drives function of the staphylococcal peroxidase inhibitor (SPIN).
J. Biol. Chem., 293, 2018
1CXP
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CRYOGENIC CRYSTAL STRUCTURE OF HUMAN MYELOPEROXIDASE ISOFORM C
Descriptor:MYELOPEROXIDASE, CHLORIDE ION, SULFATE ION, ...
Authors:Fiedler, T.J., Fenna, R.E.
Deposit date:1999-08-30
Release date:2000-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure and characterization of halide-binding sites of human myeloperoxidase at 1.8 A resolution.
J.Biol.Chem., 275, 2000
1D2V
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CRYSTAL STRUCTURE OF BROMIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5
Descriptor:MYELOPEROXIDASE, CALCIUM ION, BROMIDE ION, ...
Authors:Fiedler, T.J., Davey, C.A., Fenna, R.E.
Deposit date:1999-09-28
Release date:2000-04-24
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:X-ray crystal structure and characterization of halide-binding sites of human myeloperoxidase at 1.8 A resolution.
J.Biol.Chem., 275, 2000
1D5L
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CRYSTAL STRUCTURE OF CYANIDE-BOUND HUMAN MYELOPEROXIDASE ISOFORM C AT PH 5.5
Descriptor:MYELOPEROXIDASE, CHLORIDE ION, SULFATE ION, ...
Authors:Fiedler, T.J., Davey, C.A., Fenna, R.E.
Deposit date:1999-10-07
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
Biochemistry, 40, 2001
1D7W
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CRYSTAL STRUCTURE OF HUMAN MYELOPEROXIDASE ISOFORM C COMPLEXED WITH CYANIDE AND BROMIDE AT PH 4.0
Descriptor:MYELOPEROXIDASE, BROMIDE ION, SULFATE ION, ...
Authors:Fiedler, T.J., Fenna, R.E.
Deposit date:1999-10-20
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
Biochemistry, 40, 2001
1DNU
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STRUCTURAL ANALYSES OF HUMAN MYELOPEROXIDASE-THIOCYANATE COMPLEX
Descriptor:MYELOPEROXIDASE, THIOCYANATE ION, SULFATE ION, ...
Authors:Blair-Johnson, M., Fiedler, T.J., Fenna, R.E.
Deposit date:1999-12-16
Release date:2001-12-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
Biochemistry, 40, 2001
1DNW
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HUMAN MYELOPEROXIDASE-CYANIDE-THIOCYANATE COMPLEX
Descriptor:MYELOPEROXIDASE, THIOCYANATE ION, SULFATE ION, ...
Authors:Blair-Johnson, M., Fiedler, T.J., Fenna, R.E.
Deposit date:1999-12-16
Release date:2001-12-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
Biochemistry, 40, 2001
1MHL
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CRYSTAL STRUCTURE OF HUMAN MYELOPEROXIDASE ISOFORM C CRYSTALLIZED IN SPACE GROUP P2(1) AT PH 5.5 AND 20 DEG C
Descriptor:MYELOPEROXIDASE, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Fenna, R.E., Zeng, J., Davey, C.
Deposit date:1995-06-09
Release date:1996-01-06
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the green heme in myeloperoxidase.
Arch.Biochem.Biophys., 316, 1995
1MYP
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X-RAY CRYSTAL STRUCTURE OF CANINE MYELOPEROXIDASE AT 3 ANGSTROMS RESOLUTION
Descriptor:MYELOPEROXIDASE, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Fenna, R.E., Zeng, J.
Deposit date:1992-04-15
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray crystal structure of canine myeloperoxidase at 3 A resolution.
J.Mol.Biol., 226, 1992
3F9P
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CRYSTAL STRUCTURE OF MYELOPEROXIDASE FROM HUMAN LEUKOCYTES
Descriptor:Myeloperoxidase, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Carpena, X., Fita, I., Obinger, C.
Deposit date:2008-11-14
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Essential role of proximal histidine-asparagine interaction in Mammalian peroxidases.
J.Biol.Chem., 284, 2009
3ZS0
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HUMAN MYELOPEROXIDASE INACTIVATED BY TX2
Descriptor:MYELOPEROXIDASE LIGHT CHAIN, MYELOPEROXIDASE HEAVY CHAIN, SULFATE ION, ...
Authors:Tiden, A.K., Sjogren, T., Svensson, M., Bernlind, A., Senthilmohan, R., Auchere, F., Norman, H., Markgren, P.O., Gustavsson, S., Schmidt, S., Lundquist, S., Forbes, L.V., Magon, N.J., Jameson, G.N., Eriksson, H., Kettle, A.J.
Deposit date:2011-06-21
Release date:2011-08-31
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:2-Thioxanthines are Mechanism-Based Inactivators of Myeloperoxidase that Block Oxidative Stress During Inflammation.
J.Biol.Chem., 286, 2011
3ZS1
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HUMAN MYELOPEROXIDASE INACTIVATED BY TX5
Descriptor:MYELOPEROXIDASE LIGHT CHAIN, MYELOPEROXIDASE HEAVY CHAIN, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Tiden, A.K., Sjogren, T., Svensson, M., Bernlind, A., Senthilmohan, R., Auchere, F., Norman, H., Markgren, P.O., Gustavsson, S., Schmidt, S., Lundquist, S., Forbes, L.V., Magon, N.J., Jameson, G.N., Eriksson, H., Kettle, A.J.
Deposit date:2011-06-21
Release date:2011-08-31
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:2-Thioxanthines are Mechanism-Based Inactivators of Myeloperoxidase that Block Oxidative Stress During Inflammation.
J.Biol.Chem., 286, 2011
4C1M
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MYELOPEROXIDASE IN COMPLEX WITH THE REVESIBLE INHIBITOR HX1
Descriptor:MYELOPEROXIDASE LIGHT CHAIN, MYELOPEROXIDASE HEAVY CHAIN, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Forbes, L.V., Sjogren, T., Auchere, F., Jenkins, D.W., Thong, B., Laughton, D., Hemsley, P., Pairaudeau, G., Eriksson, H., Unitt, J.F., Kettle, A.J.
Deposit date:2013-08-13
Release date:2013-11-13
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Potent Reversible Inhibition of Myeloperoxidase by Aromatic Hydroxamates
J.Biol.Chem., 288, 2013
4DL1
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CRYSTAL STRUCTURE OF HUMAN MYELOPEROXIDASE WITH COVALENT THIOXANTHINE ANALOG
Descriptor:Myeloperoxidase light chain, Myeloperoxidase heavy chain, CHLORIDE ION, ...
Authors:Vajdos, F., Varghese, A.
Deposit date:2012-02-05
Release date:2012-03-21
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Deconstruction of activity-dependent covalent modification of heme in human neutrophil myeloperoxidase by multistage mass spectrometry (MS(4)).
Biochemistry, 51, 2012
5FIW
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CRYSTAL STRUCTURE OF HUMAN MYELOPEROXIDASE AT 1.7 ANGSTROMS RESOLUTION
Descriptor:MYELOPEROXIDASE, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Bonnefond, L., Cavarelli, J.
Deposit date:2015-10-02
Release date:2015-10-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Human Myeloperoxidase at 1.7 Angstroms Resolution
To be Published
5MFA
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CRYSTAL STRUCTURE OF HUMAN PROMYELOPEROXIDASE (PROMPO)
Descriptor:Myeloperoxidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Grishkovskaya, I., Furtmueller, P.G., Obinger, C., Djinovic-Carugo, K.
Deposit date:2016-11-17
Release date:2017-04-05
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation.
J. Biol. Chem., 292, 2017
6BMT
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CRYSTAL STRUCTURE OF A RECOMBINANT FORM OF HUMAN MYELOPEROXIDASE BOUND TO AN INHIBITOR FROM STAPHYLOCOCCUS DELPHINI
Descriptor:Myeloperoxidase, Hypothetical Protein, CALCIUM ION, ...
Authors:Ploscariu, N.T., Geisbrecht, B.V.
Deposit date:2017-11-15
Release date:2018-01-03
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Identification and structural characterization of a novel myeloperoxidase inhibitor from Staphylococcus delphini.
Arch. Biochem. Biophys., 645, 2018
5UZU
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IMMUNE EVASION BY A STAPHYLOCOCCAL PEROXIDASE INHIBITOR THAT BLOCKS MYELOPEROXIDASE
Descriptor:Uncharacterised protein, Myeloperoxidase, N-ACETYL-D-GLUCOSAMINE, ...
Authors:de Jong, N., Geisbrecht, B.V., van Strijp, J., Haas, P., Nijland, R., Ramyar, K., Fevre, C., Guerra, F., Voyich-Kane, J., van Kessel, C., Garcia, B.
Deposit date:2017-02-27
Release date:2017-07-26
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Immune evasion by a staphylococcal inhibitor of myeloperoxidase.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4EJX
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STRUCTURE OF CERULOPLASMIN-MYELOPEROXIDASE COMPLEX
Descriptor:Ceruloplasmin, Myeloperoxidase light chain, Myeloperoxidase heavy chain, ...
Authors:Samygina, V.R., Sokolov, A.V., Bourenkov, G., Vasilyev, V.B., Bartunik, H.
Deposit date:2012-04-07
Release date:2013-04-10
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (4.69 Å)
Cite:Ceruloplasmin: macromolecular assemblies with iron-containing acute phase proteins.
Plos One, 8, 2013
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