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1AIU
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HUMAN THIOREDOXIN (D60N MUTANT, REDUCED FORM)
Descriptor:THIOREDOXIN
Authors:Andersen, J.F., Gasdaska, J.R., Sanders, D.A.R., Weichsel, A., Powis, G., Montfort, W.R.
Deposit date:1997-04-25
Release date:1997-07-07
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human thioredoxin homodimers: regulation by pH, role of aspartate 60, and crystal structure of the aspartate 60 --> asparagine mutant.
Biochemistry, 36, 1997
1AUC
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HUMAN THIOREDOXIN (OXIDIZED WITH DIAMIDE)
Descriptor:THIOREDOXIN
Authors:Anderson, J.F., Sanders, D.A.R., Gasdaska, J., Weichsel, A., Powis, G., Montfort, W.R.
Deposit date:1997-08-22
Release date:1998-02-25
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human thioredoxin homodimers: regulation by pH, role of aspartate 60, and crystal structure of the aspartate 60 --> asparagine mutant.
Biochemistry, 36, 1997
1CQG
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HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, 31 STRUCTURES
Descriptor:THIOREDOXIN, REF-1 PEPTIDE
Authors:Clore, G.M., Qin, J., Gronenborn, A.M.
Deposit date:1996-04-02
Release date:1996-08-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure, 4, 1996
1CQH
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HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:THIOREDOXIN, REF-1 PEPTIDE
Authors:Clore, G.M., Qin, J., Gronenborn, A.M.
Deposit date:1996-04-02
Release date:1996-08-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure, 4, 1996
1ERT
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HUMAN THIOREDOXIN (REDUCED FORM)
Descriptor:THIOREDOXIN
Authors:Weichsel, A., Gasdaska, J.R., Powis, G., Montfort, W.R.
Deposit date:1996-02-07
Release date:1996-10-14
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer.
Structure, 4, 1996
1ERU
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HUMAN THIOREDOXIN (OXIDIZED FORM)
Descriptor:THIOREDOXIN
Authors:Weichsel, A., Gasdaska, J.R., Powis, G., Montfort, W.R.
Deposit date:1996-02-07
Release date:1996-08-01
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer.
Structure, 4, 1996
1ERV
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HUMAN THIOREDOXIN MUTANT WITH CYS 73 REPLACED BY SER (REDUCED FORM)
Descriptor:THIOREDOXIN
Authors:Weichsel, A., Gasdaska, J.R., Powis, G., Montfort, W.R.
Deposit date:1996-02-07
Release date:1996-10-14
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer.
Structure, 4, 1996
1ERW
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HUMAN THIOREDOXIN DOUBLE MUTANT WITH CYS 32 REPLACED BY SER AND CYS 35 REPLACED BY SER
Descriptor:THIOREDOXIN
Authors:Weichsel, A., Gasdaska, J.R., Powis, G., Montfort, W.R.
Deposit date:1996-02-07
Release date:1996-10-14
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer.
Structure, 4, 1996
1M7T
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SOLUTION STRUCTURE AND DYNAMICS OF THE HUMAN-ESCHERICHIA COLI THIOREDOXIN CHIMERA: INSIGHTS INTO THERMODYNAMIC STABILITY
Descriptor:Chimera of Human and E. coli thioredoxin
Authors:Dangi, B., Dobrodumov, A.V., Louis, J.M., Gronenborn, A.M.
Deposit date:2002-07-22
Release date:2002-09-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of the Human-Escherichia coli Thioredoxin Chimera: Insights into Thermodynamic Stability
Biochemistry, 41, 2002
1MDI
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HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN MUTANT HUMAN THIOREDOXIN AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB
Descriptor:THIOREDOXIN, TARGET SITE IN HUMAN NFKB
Authors:Clore, G.M., Qin, J., Gronenborn, A.M.
Deposit date:1995-02-27
Release date:1995-06-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
1MDJ
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HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB (RESIDUES 56-68 OF THE P50 SUBUNIT OF NFKB)
Descriptor:THIOREDOXIN, TARGET SITE IN HUMAN NFKB
Authors:Clore, G.M., Qin, J., Gronenborn, A.M.
Deposit date:1995-02-27
Release date:1995-06-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
1MDK
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HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB (RESIDUES 56-68 OF THE P50 SUBUNIT OF NFKB)
Descriptor:THIOREDOXIN, TARGET SITE IN HUMAN NFKB
Authors:Clore, G.M., Qin, J., Gronenborn, A.M.
Deposit date:1995-02-27
Release date:1995-06-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
1TRS
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THE HIGH-RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURES OF THE OXIDIZED AND REDUCED STATES OF HUMAN THIOREDOXIN
Descriptor:THIOREDOXIN
Authors:Clore, G.M., Qin, J., Gronenborn, A.M.
Deposit date:1994-05-10
Release date:1994-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure, 2, 1994
1TRU
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THE HIGH-RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURES OF THE OXIDIZED AND REDUCED STATES OF HUMAN THIOREDOXIN
Descriptor:THIOREDOXIN
Authors:Clore, G.M., Qin, J., Gronenborn, A.M.
Deposit date:1994-05-10
Release date:1994-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure, 2, 1994
1TRV
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THE HIGH-RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURES OF THE OXIDIZED AND REDUCED STATES OF HUMAN THIOREDOXIN
Descriptor:THIOREDOXIN
Authors:Clore, G.M., Qin, J., Gronenborn, A.M.
Deposit date:1994-05-10
Release date:1994-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure, 2, 1994
1TRW
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THE HIGH-RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURES OF THE OXIDIZED AND REDUCED STATES OF HUMAN THIOREDOXIN
Descriptor:THIOREDOXIN
Authors:Clore, G.M., Qin, J., Gronenborn, A.M.
Deposit date:1994-05-10
Release date:1994-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure, 2, 1994
2IFQ
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CRYSTAL STRUCTURE OF S-NITROSO THIOREDOXIN
Descriptor:Thioredoxin, ETHANOL
Authors:Weichsel, A., Montfort, W.R.
Deposit date:2006-09-21
Release date:2006-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Buried s-nitrosocysteine revealed in crystal structures of human thioredoxin.
Biochemistry, 46, 2007
2IIY
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CRYSTAL STRUCTURE OF S-NITROSO THIOREDOXIN
Descriptor:Thioredoxin
Authors:Weichsel, A., Montfort, W.R.
Deposit date:2006-09-28
Release date:2006-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Buried s-nitrosocysteine revealed in crystal structures of human thioredoxin.
Biochemistry, 46, 2007
3E3E
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HUMAN THIOREDOXIN DOUBLE MUTANT C35S,C73R
Descriptor:Thioredoxin, HEXAETHYLENE GLYCOL
Authors:Hall, G., Emsley, J.
Deposit date:2008-08-07
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structure of human thioredoxin exhibits a large conformational change.
Protein Sci., 19, 2010
3KD0
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HUMAN THIOREDOXIN C35S,C62S,C69S,C73S MUTANT SHOWING CADMIUM CHLORIDE BOUND TO THE ACTIVE SITE
Descriptor:Thioredoxin, CHLORIDE ION, CADMIUM ION
Authors:Hall, G., Emsley, J.
Deposit date:2009-10-22
Release date:2010-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The 1.7 A resolution crystal structure of a cadmium chloride complex with the active site of a mutant human thioredoxin
To be Published
3M9J
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CRYSTAL STRUCTURE OF HUMAN THIOREDOXIN C69/73S DOUBLE MUTANT, REDUCED FORM
Descriptor:Thioredoxin
Authors:Weichsel, A., Montfort, W.R.
Deposit date:2010-03-22
Release date:2010-08-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site.
Protein Sci., 19, 2010
3M9K
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CRYSTAL STRUCTURE OF HUMAN THIOREDOXIN C69/73S DOUBLE-MUTANT, OXIDIZED FORM
Descriptor:Thioredoxin, SULFATE ION, (4S,5S)-1,2-DITHIANE-4,5-DIOL
Authors:Weichsel, A., Montfort, W.R.
Deposit date:2010-03-22
Release date:2010-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of human thioredoxin revealing an unraveled helix and exposed S-nitrosation site.
Protein Sci., 19, 2010
3TRX
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HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF REDUCED RECOMBINANT HUMAN THIOREDOXIN IN SOLUTION
Descriptor:THIOREDOXIN
Authors:Forman-Kay, J.D., Clore, G.M., Gronenborn, A.M.
Deposit date:1990-12-17
Release date:1992-01-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution.
Biochemistry, 30, 1991
4OO4
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CRYSTAL STRUCTURE OF HUMAN THIOREDOXIN MUTANT
Descriptor:Thioredoxin
Authors:The, J., Weichsel, A., Montfort, W.R.
Deposit date:2014-01-30
Release date:2014-02-12
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Crystal Structure of a Thioredoxin Mutant Displays a Dynamic N-terminal Loop Surrounding an S-nitrosation Site
To be Published
4OO5
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CRYSTAL STRUCTURE OF S-NITROSATED HUMAN THIOREDOXIN MUTANT
Descriptor:Thioredoxin
Authors:The, J., Weichsel, A., Montfort, W.R.
Deposit date:2014-01-30
Release date:2014-02-12
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystal Structure of a Thioredoxin Mutant Displays a Dynamic N-terminal Loop Surrounding an S-nitrosation Site
To be Published
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