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1RW5
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SOLUTION STRUCTURE OF HUMAN PROLACTIN
Descriptor:Prolactin
Authors:Teilum, K., Hoch, J., Martial, J.A., Kragelund, B.B.
Deposit date:2003-12-16
Release date:2005-02-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of human prolactin
J.Mol.Biol., 351, 2005
2Q98
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X-RAY STRUCTURE OF A PROLACTIN ANTAGONIST
Descriptor:Prolactin
Authors:Broutin, I.J.L., Ducruix, A., Jomain, J.B., Goffin, V.
Deposit date:2007-06-12
Release date:2007-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL.
J.Biol.Chem., 282, 2007
3D48
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CRYSTAL STRUCTURE OF A PROLACTIN RECEPTOR ANTAGONIST BOUND TO THE EXTRACELLULAR DOMAIN OF THE PROLACTIN RECEPTOR
Descriptor:Prolactin, Prolactin receptor, CARBONATE ION
Authors:Svensson, L.A., Breinholt, J.
Deposit date:2008-05-14
Release date:2008-06-03
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor
J.Biol.Chem., 283, 2008
3EW3
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THE 1:2 COMPLEX BETWEEN A NTERMINAL ELONGATED PROLACTIN AND THE EXTRA CELLULAR DOMAIN OF THE RAT PROLACTIN RECEPTOR
Descriptor:Prolactin, Prolactin receptor
Authors:Broutin, I., Jomain, J.B., England, P., Goffin, V.
Deposit date:2008-10-14
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2.
J.Biol.Chem., 285, 2010
3MZG
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CRYSTAL STRUCTURE OF A HUMAN PROLACTIN RECEPTOR ANTAGONIST IN COMPLEX WITH THE EXTRACELLULAR DOMAIN OF THE HUMAN PROLACTIN RECEPTOR
Descriptor:Prolactin, Prolactin receptor, SODIUM ION, ...
Authors:Kulkarni, M.V., Tettamanzi, M.C., Murphy, J.W., Keeler, C., Myszka, D.G., Chayen, N.E., Lolis, E.J., Hodsdon, M.E.
Deposit date:2010-05-12
Release date:2010-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3N06
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A MUTANT HUMAN PROLACTIN RECEPTOR ANTAGONIST H27A IN COMPLEX WITH THE EXTRACELLULAR DOMAIN OF THE HUMAN PROLACTIN RECEPTOR
Descriptor:Prolactin, Prolactin receptor, SODIUM ION, ...
Authors:Kulkarni, M.V., Tettamanzi, M.C., Murphy, J.W., Keeler, C., Myszka, D.G., Chayen, N.E., Lolis, E.J., Hodsdon, M.E.
Deposit date:2010-05-13
Release date:2010-09-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3N0P
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A MUTANT HUMAN PROLACTIN RECEPTOR ANTAGONIST H30A IN COMPLEX WITH THE EXTRACELLULAR DOMAIN OF THE HUMAN PROLACTIN RECEPTOR
Descriptor:Prolactin, Prolactin receptor, SODIUM ION, ...
Authors:Kulkarni, M.V., Tettamanzi, M.C., Murphy, J.W., Keeler, C., Myszka, D.G., Chayen, N.E., Lolis, E.J., Hodsdon, M.E.
Deposit date:2010-05-14
Release date:2010-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NCB
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A MUTANT HUMAN PROLACTIN RECEPTOR ANTAGONIST H180A IN COMPLEX WITH THE EXTRACELLULAR DOMAIN OF THE HUMAN PROLACTIN RECEPTOR
Descriptor:Prolactin, Prolactin receptor, CARBONATE ION, ...
Authors:Kulkarni, M.V., Tettamanzi, M.C., Murphy, J.W., Keeler, C., Myszka, D.G., Chayen, N.E., Lolis, E.J., Hodsdon, M.E.
Deposit date:2010-06-04
Release date:2010-09-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NCC
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A HUMAN PROLACTIN RECEPTOR ANTAGONIST IN COMPLEX WITH THE MUTANT EXTRACELLULAR DOMAIN H188A OF THE HUMAN PROLACTIN RECEPTOR
Descriptor:Prolactin, Prolactin receptor, SODIUM ION, ...
Authors:Kulkarni, M.V., Tettamanzi, M.C., Murphy, J.W., Keeler, C., Myszka, D.G., Chayen, N.E., Lolis, E.J., Hodsdon, M.E.
Deposit date:2010-06-04
Release date:2010-09-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NCE
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A MUTANT HUMAN PROLACTIN RECEPTOR ANTAGONIST H27A IN COMPLEX WITH THE MUTANT EXTRACELLULAR DOMAIN H188A OF THE HUMAN PROLACTIN RECEPTOR
Descriptor:Prolactin, Prolactin receptor, SODIUM ION, ...
Authors:Kulkarni, M.V., Tettamanzi, M.C., Murphy, J.W., Keeler, C., Myszka, D.G., Chayen, N.E., Lolis, E.J., Hodsdon, M.E.
Deposit date:2010-06-04
Release date:2010-09-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NCF
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A MUTANT HUMAN PROLACTIN RECEPTOR ANTAGONIST H30A IN COMPLEX WITH THE MUTANT EXTRACELLULAR DOMAIN H188A OF THE HUMAN PROLACTIN RECEPTOR
Descriptor:Prolactin, Prolactin receptor, SODIUM ION, ...
Authors:Kulkarni, M.V., Tettamanzi, M.C., Murphy, J.W., Keeler, C., Myszka, D.G., Chayen, N.E., Lolis, E.J., Hodsdon, M.E.
Deposit date:2010-06-04
Release date:2010-09-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
3NPZ
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PROLACTIN RECEPTOR (PRLR) COMPLEXED WITH THE NATURAL HORMONE (PRL)
Descriptor:Prolactin, Prolactin receptor
Authors:Van Agthoven, J., England, P., Goffin, V., Broutin, I.
Deposit date:2010-06-29
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.
J.Mol.Biol., 404, 2010