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1CDH
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STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES
Descriptor:T CELL SURFACE GLYCOPROTEIN CD4
Authors:Ryu, S.E., Truneh, A., Sweet, R.W., Hendrickson, W.A.
Deposit date:1994-01-26
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices.
Structure, 2, 1994
1CDI
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STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES
Descriptor:T CELL SURFACE GLYCOPROTEIN CD4
Authors:Ryu, S.E., Truneh, A., Sweet, R.W., Hendrickson, W.A.
Deposit date:1994-01-26
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices.
Structure, 2, 1994
1CDJ
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
1CDU
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH PHE 43 REPLACED BY VAL
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
1CDY
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH GLY 47 REPLACED BY SER
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
1Q68
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SOLUTION STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 AND PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK FRAGMENTS
Descriptor:T-cell surface glycoprotein CD4, Proto-oncogene tyrosine-protein kinase LCK, ZINC ION
Authors:Kim, P.W., Sun, Z.Y., Blacklow, S.C., Wagner, G., Eck, M.J.
Deposit date:2003-08-12
Release date:2003-11-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8.
Science, 301, 2003
1RZK
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HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIBODY 17B, ...
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1WBR
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SOLUTION STRUCTURE OF THE HUMAN CD4 (403-419) RECEPTOR PEPTIDE, NMR, 32 STRUCTURES
Descriptor:CD4 RECEPTOR
Authors:Willbold, D., Roesch, P.
Deposit date:1996-12-20
Release date:1997-03-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Human CD4 (403-419) Receptor Peptide.
J.Biomed.Sci., 3, 1996
1WIO
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, TETRAGONAL CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1WIP
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, MONOCLINIC CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1WIQ
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, TRIGONAL CRYSTAL FORM
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Kwong, P.D., Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
2B4C
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CRYSTAL STRUCTURE OF HIV-1 JR-FL GP120 CORE PROTEIN CONTAINING THE THIRD VARIABLE REGION (V3) COMPLEXED WITH CD4 AND THE X5 ANTIBODY
Descriptor:envelope glycoprotein, T-cell surface glycoprotein CD4, anti-HIV-1 gp120 immunoglobulin X5 light chain, ...
Authors:Huang, C., Tang, M., Zhang, M.Y., Majeed, S., Montabana, E., Stanfield, R.L., Dimitrov, D.S., Korber, B., Sodroski, J., Wilson, I.A., Wyatt, R., Kwong, P.D.
Deposit date:2005-09-23
Release date:2005-11-15
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of a V3-containing HIV-1 gp120 core.
Science, 310, 2005
2KLU
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NMR STRUCTURE OF THE TRANSMEMBRANE AND CYTOPLASMIC DOMAINS OF HUMAN CD4
Descriptor:T-cell surface glycoprotein CD4
Authors:Wittlich, M., Willbold, D.
Deposit date:2009-07-08
Release date:2009-10-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of the transmembrane and cytoplasmic domains of human CD4 in micelles.
Biochim.Biophys.Acta, 1798, 2010
2NXY
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HIV-1 GP120 ENVELOPE GLYCOPROTEIN(S334A) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, ...
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NXZ
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HIV-1 GP120 ENVELOPE GLYCOPROTEIN (T257S, S334A, S375W) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, ...
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY0
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HIV-1 GP120 ENVELOPE GLYCOPROTEIN (M95W, W96C, T257S, V275C, S334A, S375W, A433M) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, ...
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY1
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HIV-1 GP120 ENVELOPE GLYCOPROTEIN (I109C, T257S, S334A, S375W, Q428C) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, ...
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY2
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HIV-1 GP120 ENVELOPE GLYCOPROTEIN (T123C, T257S, S334A, S375W, G431C) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, ...
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY3
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HIV-1 GP120 ENVELOPE GLYCOPROTEIN (K231C, T257S, E267C, S334A, S375W) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, ...
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY4
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HIV-1 GP120 ENVELOPE GLYCOPROTEIN (K231C, T257S, E268C, S334A, S375W) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, ...
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY5
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HIV-1 GP120 ENVELOPE GLYCOPROTEIN (M95W, W96C, I109C, T257S, V275C, S334A, S375W, Q428C, A433M) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, ...
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
3CD4
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REFINEMENT AND ANALYSIS OF THE FIRST TWO DOMAINS OF HUMAN CD4
Descriptor:T CELL SURFACE GLYCOPROTEIN CD4
Authors:Garrett, T.P.J., Wang, J., Yan, Y., Harrison, S.C.
Deposit date:1992-07-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refinement and analysis of the structure of the first two domains of human CD4
J.Mol.Biol., 234, 1993
3J70
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MODEL OF GP120, INCLUDING VARIABLE REGIONS, IN COMPLEX WITH CD4 AND 17B
Descriptor:monoclonal antibody 17b light chain, monoclonal antibody 17b heavy chain, T-cell surface glycoprotein CD4, ...
Authors:Rasheed, M., Bettadapura, R., Bajaj, C.
Deposit date:2014-04-22
Release date:2015-08-26
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State.
Structure, 23, 2015
3JCB
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STRUCTURE OF SIMIAN IMMUNODEFICIENCY VIRUS ENVELOPE SPIKES BOUND WITH CD4 AND MONOCLONAL ANTIBODY 36D5
Descriptor:Envelope glycoprotein gp120, Antibody 36D5 light chain, Antibody 36D5 heavy chain, ...
Authors:Hu, G., Liu, J., Roux, K., Taylor, K.A.
Deposit date:2015-11-25
Release date:2017-05-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY
Cite:Structure of Simian Immunodeficiency Virus Envelope Spikes Bound with CD4 and Monoclonal Antibody 36D5.
J. Virol., 91, 2017
3JCC
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STRUCTURE OF SIMIAN IMMUNODEFICIENCY VIRUS ENVELOPE SPIKES BOUND WITH CD4 AND MONOCLONAL ANTIBODY 36D5
Descriptor:Envelope glycoprotein gp120, Antibody 36D5 light chain, Antibody 36D5 heavy chain, ...
Authors:Hu, G., Liu, J., Roux, K., Taylor, K.A.
Deposit date:2015-11-25
Release date:2017-05-10
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY
Cite:Structure of Simian Immunodeficiency Virus Envelope Spikes Bound with CD4 and Monoclonal Antibody 36D5.
J. Virol., 91, 2017
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