6P8H | | CRYSTAL STRUCTURE OF CDK4 IN COMPLEX WITH CYCLIND1 AND P21 | | Descriptor: | G1/S-specific cyclin-D1, Cyclin-dependent kinase 4, Cyclin-dependent kinase inhibitor 1 | | Authors: | Guiley, K.Z., Stevenson, J.W., Lou, K., Barkovich, K.J., Bunch, K., Tripathi, S.M., Shokat, K.M., Rubin, S.M. | | Deposit date: | 2019-06-07 | | Release date: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.
Science, 366, 2019
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6CIV | |
6CIX | |
6CEJ | |
6CBI | | PCNA IN COMPLEX WITH INHIBITOR | | Descriptor: | Proliferating cell nuclear antigen, GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS, SULFATE ION | | Authors: | Bruning, J.B., Wegener, K.L. | | Deposit date: | 2018-02-03 | | Release date: | 2018-07-04 | | Last modified: | 2020-01-29 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
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5E0U | |
4RJF | |
2ZVV | | CRYSTAL STRUCTURE OF PROLIFERATING CELLULAR NUCLEAR ANTIGEN 1 AND SHORT PEPTIDE FROM HUMAN P21 | | Descriptor: | Proliferating cellular nuclear antigen 1, Cyclin-dependent kinase inhibitor 1, SULFATE ION | | Authors: | Strzalka, W., Oyama, T., Tori, K., Morikawa, K. | | Deposit date: | 2008-11-21 | | Release date: | 2009-06-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of the Arabidopsis thaliana proliferating cell nuclear antigen 1 and 2 proteins complexed with the human p21 C-terminal segment
Protein Sci., 18, 2009
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2ZVW | | CRYSTAL STRUCTURE OF PROLIFERATING CELL NUCLEAR ANTIGEN 2 AND SHORT PEPTIDE FROM HUMAN P21 | | Descriptor: | Proliferating cell nuclear antigen 2, Cyclin-dependent kinase inhibitor 1, SULFATE ION | | Authors: | Strzalka, W., Oyama, T., Tori, K., Morikawa, K. | | Deposit date: | 2008-11-21 | | Release date: | 2009-06-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of the Arabidopsis thaliana proliferating cell nuclear antigen 1 and 2 proteins complexed with the human p21 C-terminal segment
Protein Sci., 18, 2009
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1AXC | | HUMAN PCNA | | Descriptor: | PCNA, P21/WAF1 | | Authors: | Gulbis, J.M., Kuriyan, J. | | Deposit date: | 1997-10-14 | | Release date: | 1998-01-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA.
Cell(Cambridge,Mass.), 87, 1996
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