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6NRW
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CRYSTAL STRUCTURE OF DPR1 IG1 BOUND TO DIP-ETA IG1
Descriptor:DPR1, Dpr-interacting protein eta, isoform B, ...
Authors:Cheng, S., Park, Y.J., Kurleto, J.D., Ozkan, E.
Deposit date:2019-01-24
Release date:2019-02-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
6NRX
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CRYSTAL STRUCTURE OF DIP-ETA IG1 HOMODIMER
Descriptor:Dpr-interacting protein eta, isoform B, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Cheng, S., Park, Y.J., Kurleto, J.D., Ozkan, E.
Deposit date:2019-01-24
Release date:2019-02-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
6NRZ
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CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM CHLAMYDIA TRACHOMATIS COMPLEXED WITH L-LYSINE AND ADENOSINE
Descriptor:Lysine--tRNA ligase, LYSINE, ADENOSINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-01-24
Release date:2019-02-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and Adenosine
to be published
6NS0
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CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM CHLAMYDIA TRACHOMATIS COMPLEXED WITH L-LYSINE AND CLADOSPORIN
Descriptor:Lysine--tRNA ligase, LYSINE, cladosporin, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-01-24
Release date:2019-02-06
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Lysyl-tRNA Synthetase from Chlamydia trachomatis with complexed with L-lysine and Cladosporin
to be published
6NS1
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CRYSTAL STRUCTURE OF DIP-GAMMA IG1+IG2
Descriptor:Dpr-interacting protein gamma, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE
Authors:Cheng, S., Park, Y.J., Kurleto, J.D., Ozkan, E.
Deposit date:2019-01-24
Release date:2019-02-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
6QJE
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STRUCTURE OF HUMAN GALACTOKINASE 1 BOUND WITH 4-{[2-(METHYLSULFONYL)-1H-IMIDAZOL-1-YL]METHYL}-1,3-THIAZOLE
Descriptor:Galactokinase, BETA-D-GALACTOSE, 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, ...
Authors:Mackinnon, S.R., Bezerra, G.A., Zhang, M., Foster, W., Krojer, T., Brandao-Neto, J., Douangamath, A., Arrowsmith, C., Edwards, A., Bountra, C., Brennan, P., Lai, K., Yue, W.W.
Deposit date:2019-01-24
Release date:2019-02-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of human galactokinase 1 bound with 4-{[2-(Methylsulfonyl)-1H-imidazol-1-yl]methyl}-1,3-thiazole
To Be Published
6QJH
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CRYO-EM STRUCTURE OF HEPARIN-INDUCED 2N4R TAU SNAKE FILAMENTS
Descriptor:Microtubule-associated protein tau
Authors:Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJM
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CRYO-EM STRUCTURE OF HEPARIN-INDUCED 2N4R TAU TWISTER FILAMENTS
Descriptor:Microtubule-associated protein tau
Authors:Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJP
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CRYO-EM STRUCTURE OF HEPARIN-INDUCED 2N4R TAU JAGGED FILAMENTS
Descriptor:Microtubule-associated protein tau
Authors:Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJQ
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CRYO-EM STRUCTURE OF HEPARIN-INDUCED 2N3R TAU FILAMENTS
Descriptor:Microtubule-associated protein tau
Authors:Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6J9K
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APO-ACRIIC2
Descriptor:AcrIIC2, MAGNESIUM ION
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Method:X-RAY DIFFRACTION (2.234 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins
To Be Published
6J9L
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FNOBH+ACRIIC2
Descriptor:AcrIIC2, HNH endonuclease family protein
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins
To Be Published
6J9M
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NMEBH+ACRIIC2
Descriptor:CRISPR-associated endonuclease Cas9, AcrIIC2
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins
To Be Published
6J9N
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NMEHNH+ACRIIC3
Descriptor:CRISPR-associated endonuclease Cas9, AcrIIC3
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Method:X-RAY DIFFRACTION (2.606 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins
To Be Published
6NRP
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PUTATIVE SHORT-CHAIN DEHYDROGENASE/REDUCTASE (SDR) FROM ACINETOBACTER BAUMANNII
Descriptor:3-oxoacyl-ACP reductase FabG
Authors:Cross, E.M., Smith, K.M., Shaw, K.I., Aragao, D., Forwood, J.K.
Deposit date:2019-01-23
Release date:2019-02-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Putative short-chain dehydrogenase/reductase (SDR) from Acinetobacter baumannii
To Be Published
6J99
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CRYO-EM STRUCTURE OF HUMAN DOT1L IN COMPLEX WITH AN H2B-MONOUBIQUITINATED NUCLEOSOME
Descriptor:Histone H3, Histone H4, Histone H2A, ...
Authors:Yao, T., Huang, J.
Deposit date:2019-01-22
Release date:2019-02-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of the crosstalk between histone H2B monoubiquitination and H3 lysine 79 methylation on nucleosome.
Cell Res., 2019
6NR2
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CRYO-EM STRUCTURE OF THE TRPM8 ION CHANNEL IN COMPLEX WITH THE MENTHOL ANALOG WS-12 AND PI(4,5)P2
Descriptor:Transient receptor potential cation channel subfamily M member 8, (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl icosa-5,8,11,14-tetraenoate, (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide
Authors:Yin, Y., Le, S.C., Hsu, A.L., Borgnia, M.J., Yang, H., Lee, S.-Y.
Deposit date:2019-01-22
Release date:2019-02-20
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.
Science, 363, 2019
6NR3
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CRYO-EM STRUCTURE OF THE TRPM8 ION CHANNEL IN COMPLEX WITH HIGH OCCUPANCY ICILIN, PI(4,5)P2, AND CALCIUM
Descriptor:Transient receptor potential cation channel subfamily M member 8, Icilin, (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl icosa-5,8,11,14-tetraenoate, ...
Authors:Yin, Y., Le, S.C., Hsu, A.L., Borgnia, M.J., Yang, H., Lee, S.-Y.
Deposit date:2019-01-22
Release date:2019-02-20
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.
Science, 363, 2019
6NR4
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CRYO-EM STRUCTURE OF THE TRPM8 ION CHANNEL WITH LOW OCCUPANCY ICILIN, PI(4,5)P2, AND CALCIUM
Descriptor:Transient receptor potential cation channel subfamily M member 8
Authors:Yin, Y., Le, S.C., Hsu, A.L., Borgnia, M.J., Yang, H., Lee, S.-Y.
Deposit date:2019-01-22
Release date:2019-02-20
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.
Science, 363, 2019
6J93
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CRYSTAL STRUCTURE OF PEPTIDYL-TRNA HYDROLASE FROM ACINETOBACTER BAUMANNII AT 0.95 A RESOLUTION
Descriptor:Peptidyl-tRNA hydrolase, 1,2-ETHANEDIOL
Authors:Viswanathan, V., Sharma, P., Singh, P.K., Iqbal, N., Sharma, S., Singh, T.P.
Deposit date:2019-01-21
Release date:2019-02-06
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Crystal structure of Peptidyl-tRNA hydrolase form apo at 0.95 A resolution.
To Be Published
6NQD
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CRYO-EM STRUCTURE OF T/F100 SOSIP.664 HIV-1 ENV TRIMER IN COMPLEX WITH 8ANC195 FAB
Descriptor:T/F100 Env gp120, T/F100 Env gp41, 8ANC195 G52K5 heavy chain, ...
Authors:Fang, Q., Rossmann, M.G.
Deposit date:2019-01-21
Release date:2019-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:A sequestered fusion peptide in the structure of an HIV-1 transmitted founder envelope trimer.
Nat Commun, 10, 2019
6NQM
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CRYSTAL STRUCTURE OF HUMAN LSD1
Descriptor:Lysine-specific histone demethylase 1A, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Tan, A.H.Y., Tu, W., McCuaig, R., Donovan, T., Tsimbalyuk, S., Forwood, J.K., Rao, S.
Deposit date:2019-01-21
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Lysine-specific histone demethylase 1A regulates macrophage polarisation and checkpoint molecules in the tumor microenvironment of triple-negative breast cancer.
to be published
6NQU
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HUMAN LSD1 IN COMPLEX WITH GSK2879552
Descriptor:Lysine-specific histone demethylase 1A, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-5-[(9~{S},11~{R})-15,16-dimethyl-11-oxidanyl-5,7-bis(oxidanylidene)-9-phenyl-2,4,6,12-tetrazabicyclo[11.4.0]heptadeca-1(17),13,15-trien-2-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate
Authors:Tan, A.H.Y., Tu, W., McCuaig, R., Donovan, T., Tsimbalyuk, S., Forwood, J.K., Rao, S.
Deposit date:2019-01-21
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Lysine-specific histone demethylase 1A regulates macrophage polarization and checkpoint molecules in the tumor microenvironment of triple-negative breast cancer.
to be published
6J8G
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STRUCTURE OF HUMAN VOLTAGE-GATED SODIUM CHANNEL NAV1.7 IN COMPLEX WITH AUXILIARY BETA SUBUNITS, HUWENTOXIN-IV AND SAXITOXIN (Y1755 UP)
Descriptor:Sodium channel subunit beta-2, Sodium channel protein type 9 subunit alpha, Sodium channel subunit beta-1, ...
Authors:Shen, H., Liu, D., Lei, J., Yan, N.
Deposit date:2019-01-19
Release date:2019-02-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins.
Science, 2019
6J8H
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STRUCTURE OF HUMAN VOLTAGE-GATED SODIUM CHANNEL NAV1.7 IN COMPLEX WITH AUXILIARY BETA SUBUNITS, HUWENTOXIN-IV AND SAXITOXIN (Y1755 DOWN)
Descriptor:Sodium channel subunit beta-2, Sodium channel protein type 9 subunit alpha, Sodium channel subunit beta-1, ...
Authors:Shen, H., Liu, D., Lei, J., Yan, N.
Deposit date:2019-01-19
Release date:2019-02-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins.
Science, 2019