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6E13
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PSEUDOMONAS PUTIDA PQQB WITH A NON-PHYSIOLOGICAL ZINC AT THE ACTIVE SITE BINDS THE SUBSTRATE MIMIC, 5-CYSTEINYL-3,4-DIHYDROXYPHENYLALANINE (5-CYS-DOPA), NON-SPECIFICALLY BUT SUPPORTS THE PROPOSED FUNCTION OF THE ENZYME IN PYRROLOQUINOLINE QUINONE BIOSYNTHESIS.
Descriptor:Coenzyme PQQ synthesis protein B, ZINC ION, CHLORIDE ION, ...
Authors:Evans III, R.L., Wilmot, C.M.
Deposit date:2018-07-09
Release date:2019-05-22
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway.
J.Am.Chem.Soc., 141, 2019