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6YLE
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RIX1-REA1 PRE-60S PARTICLE - RIX1-SUBCOMPLEX, BODY 3 (RIGID BODY REFINEMENT)
Descriptor:Pre-rRNA-processing protein IPI3, Pre-rRNA-processing protein RIX1, Pre-rRNA-processing protein IPI1
Authors:Kater, L., Beckmann, R.
Deposit date:2020-04-07
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 2020
6YLF
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RIX1-REA1 PRE-60S PARTICLE - REA1, BODY 3 (RIGID BODY REFINEMENT, COMPOSITE STRUCTURE OF REA1 RING AND TAIL)
Descriptor:Midasin, Ribosome assembly protein 4
Authors:Kater, L., Beckmann, R.
Deposit date:2020-04-07
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 2020
6YLG
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RIX1-REA1 PRE-60S PARTICLE - 60S CORE, BODY 1 (RIGID BODY REFINEMENT)
Descriptor:25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Kater, L., Beckmann, R.
Deposit date:2020-04-07
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 2020
6YLH
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RIX1-REA1 PRE-60S PARTICLE - FULL COMPOSITE STRUCTURE
Descriptor:25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Kater, L., Beckmann, R.
Deposit date:2020-04-07
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 2020
6YLX
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PRE-60S STATE NE1 (TAP-FLAG-NOP53)
Descriptor:60S ribosomal protein L3, 60S ribosomal protein L4-A, 60S ribosomal protein L6-A, ...
Authors:Kater, L., Beckmann, R.
Deposit date:2020-04-07
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 2020
6YLY
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PRE-60S STATE NE2 (TAP-FLAG-NOP53)
Descriptor:60S ribosomal protein L2-A, 60S ribosomal protein L28, 60S ribosomal protein L3, ...
Authors:Kater, L., Beckmann, R.
Deposit date:2020-04-07
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 2020
6YSA
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA LEGUMAIN ISOFORM BETA IN ZYMOGEN STATE
Descriptor:Vacuolar-processing enzyme beta-isozyme, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ...
Authors:Dall, E., Zauner, F.B., Brandstetter, H.
Deposit date:2020-04-21
Release date:2020-07-29
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition
J.Biol.Chem., 2020
6YY5
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR (PFEA) IN COMPLEX WITH TCV_L5
Descriptor:Ferric enterobactin receptor, FE (III) ION, ~{N}-[2-[[(2~{S})-3-[[(2~{S})-3-[[1-[2-[2-[2-[4-[4-[5-(acetamidomethyl)-2-oxidanylidene-1,3-oxazolidin-3-yl]-2-fluoranyl-phenyl]piperazin-1-yl]-2-oxidanylidene-ethoxy]ethoxy]ethyl]-1,2,3-triazol-4-yl]methylamino]-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-oxidanylidene-propyl]amino]-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-oxidanylidene-propyl]amino]-2-oxidanylidene-ethyl]-2,3-bis(oxidanyl)benzamide
Authors:Naismith, J.H., Moynie, L.M.
Deposit date:2020-05-04
Release date:2020-07-29
Method:X-RAY DIFFRACTION (2.717 Å)
Cite:Crystal structure of the ferric enterobactin receptor (PfeA) in complex with TCV-L5
To Be Published
6Z2V
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CLK3 A319V MUTANT BOUND WITH BETA-CARBOLINE KH-CARB13 (CPD 3)
Descriptor:Dual specificity protein kinase CLK3, (4~{S})-7,8-bis(chloranyl)-9-methyl-1-oxidanylidene-spiro[2,4-dihydropyrido[3,4-b]indole-3,4'-piperidine]-4-carbonitrile, POTASSIUM ION, ...
Authors:Schroeder, M., Chaikuad, A., Bracher, F., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2020-05-18
Release date:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:CLK3 A319V mutant bound with beta-carboline KH-CARB13 (Cpd 3)
To Be Published
6Z33
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR (PFEA) IN COMPLEX WITH BCV
Descriptor:Ferric enterobactin receptor, ~{N}-[(5~{S})-5-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-6-oxidanylidene-6-(prop-2-ynylamino)hexyl]-2,3-bis(oxidanyl)benzamide, 1,2-ETHANEDIOL, ...
Authors:Naismith, J.H., Moynie, L.M.
Deposit date:2020-05-19
Release date:2020-07-29
Method:X-RAY DIFFRACTION (2.711 Å)
Cite:Crystal structure of the ferric enterobactin receptor (PfeA) in complex with BCV
To Be Published
6Z4C
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THE STRUCTURE OF THE N-TERMINAL DOMAIN OF RSSB FROM E. COLI
Descriptor:Regulator of RpoS
Authors:Zeth, K., Dimce, M., Terrence, D.M., Schuenemann, V., Dougan, D.
Deposit date:2020-05-25
Release date:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insight into the RssB-Mediated Recognition and Delivery of sigmasto the AAA+ Protease, ClpXP.
Biomolecules, 10, 2020
6Z4E
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THE STRUCTURE OF THE C-TERMINAL DOMAIN OF RSSB FROM E. COLI
Descriptor:Regulator of RpoS
Authors:Zeth, K., Dimce, M., Terrence, D.M., Schuenemann, V., Dougan, D.
Deposit date:2020-05-25
Release date:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insight into the RssB-Mediated Recognition and Delivery of sigmasto the AAA+ Protease, ClpXP.
Biomolecules, 10, 2020
6Z6B
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STRUCTURE OF FULL-LENGTH LA CROSSE VIRUS L PROTEIN (POLYMERASE)
Descriptor:RNA (5'-R(P*AP*GP*UP*AP*GP*UP*GP*UP*GP*C)-3'), RNA (5'-R(P*UP*UP*AP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), RNA (5'-R(*GP*CP*UP*AP*CP*UP*AP*A)-3'), ...
Authors:Cusack, S., Gerlach, P., Reguera, J.
Deposit date:2020-05-28
Release date:2020-07-29
Method:X-RAY DIFFRACTION (3.961 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
6Z6G
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CRYO-EM STRUCTURE OF LA CROSSE VIRUS POLYMERASE AT PRE-INITIATION STAGE
Descriptor:5'vRNA 1-10, 5'vRNA 9-16, 3'vRNA 1-16, ...
Authors:Arragain, B., Effantin, G., Gerlach, P., Reguera, J., Schoehn, G., Cusack, S., Malet, H.
Deposit date:2020-05-28
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
6Z6J
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CRYO-EM STRUCTURE OF YEAST LSO2 BOUND TO 80S RIBOSOMES UNDER NATIVE CONDITION
Descriptor:18S rRNA, Protein LSO2, 25S rRNA, ...
Authors:Wells, J.N., Buschauer, R., Mackens-Kiani, T., Best, K., Kratzat, H., Berninghausen, O., Becker, T., Cheng, J., Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6Z6K
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CRYO-EM STRUCTURE OF YEAST RECONSTITUTED LSO2 BOUND TO 80S RIBOSOMES
Descriptor:18S rRNA, Protein LSO2, 25S rRNA, ...
Authors:Wells, J.N., Buschauer, R., Mackens-Kiani, T., Best, K., Kratzat, H., Berninghausen, O., Becker, T., Cheng, J., Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6Z6L
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CRYO-EM STRUCTURE OF HUMAN CCDC124 BOUND TO 80S RIBOSOMES
Descriptor:28S rRNA, 5S rRNA, 5.8S rRNA, ...
Authors:Wells, J.N., Buschauer, R., Mackens-Kiani, T., Best, K., Kratzat, H., Berninghausen, O., Becker, T., Cheng, J., Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6Z6M
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CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOMES BOUND TO EBP1, EEF2 AND SERBP1
Descriptor:28S rRNA, 5S rRNA, 5.8S rRNA, ...
Authors:Wells, J.N., Buschauer, R., Mackens-Kiani, T., Best, K., Kratzat, H., Berninghausen, O., Becker, T., Cheng, J., Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6Z6N
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CRYO-EM STRUCTURE OF HUMAN EBP1-80S RIBOSOMES (FOCUS ON EBP1)
Descriptor:28S rRNA, 5S rRNA, 5.8S rRNA, ...
Authors:Wells, J.N., Buschauer, R., Mackens-Kiani, T., Best, K., Kratzat, H., Berninghausen, O., Becker, T., Cheng, J., Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6Z7F
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C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-(2-(1H-IMIDAZOL-4-YL)ETHYL)-4-ACETAMIDO-3-(BENZYLOXY)BENZAMIDE
Descriptor:Bromodomain-containing protein 2, DI(HYDROXYETHYL)ETHER, 1,2-ETHANEDIOL, ...
Authors:Chung, C.
Deposit date:2020-05-30
Release date:2020-07-29
Method:X-RAY DIFFRACTION (1.605 Å)
Cite:The Design and Synthesis of a Highly Selective and In Vivo Capable Inhibitor of the Second Bromodomain (BD2) of the Bromodomain and Extra Terminal Domain (BET) Family of Proteins.
J.Med.Chem., 2020
6Z7G
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N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(2-(1H-IMIDAZOL-4-YL)ETHYL)-4-ACETAMIDO-3-(BENZYLOXY)BENZAMIDE
Descriptor:Bromodomain-containing protein 4, N-(2-(1H-imidazol-4-yl)ethyl)-4-acetamido-3-(benzyloxy)benzamide
Authors:Chung, C.
Deposit date:2020-05-30
Release date:2020-07-29
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:The Design and Synthesis of a Highly Selective and In Vivo Capable Inhibitor of the Second Bromodomain (BD2) of the Bromodomain and Extra Terminal Domain (BET) Family of Proteins.
J.Med.Chem., 2020
6Z7L
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N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH GSK789
Descriptor:Bromodomain-containing protein 4, (3~{R},4~{R})-~{N}-cyclohexyl-4-[[5-(furan-2-yl)-3-methyl-2-oxidanylidene-1~{H}-1,7-naphthyridin-8-yl]amino]-1-methyl-piperidine-3-carboxamide
Authors:Chung, C.
Deposit date:2020-05-31
Release date:2020-07-29
Method:X-RAY DIFFRACTION (1.624 Å)
Cite:GSK789: A Selective Inhibitor of the First Bromodomains (BD1) of the Bromo and Extra Terminal Domain (BET) Proteins.
J.Med.Chem., 2020
6Z7M
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N-TERMINAL BROMODOMAIN OF HUMAN BRD4 (3R,4R)-N-CYCLOHEXYL-4-((3-METHYL-2-OXO-1,2-DIHYDRO-1,7-NAPHTHYRIDIN-8-YL)AMINO)PIPERIDINE-3-CARBOXAMIDE
Descriptor:Bromodomain-containing protein 4, (3R,4R)-N-cyclohexyl-4-((3-methyl-2-oxo-1,2-dihydro-1,7-naphthyridin-8-yl)amino)piperidine-3-carboxamide
Authors:Chung, C.
Deposit date:2020-05-31
Release date:2020-07-29
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:GSK789: A Selective Inhibitor of the First Bromodomains (BD1) of the Bromo and Extra Terminal Domain (BET) Proteins.
J.Med.Chem., 2020
6Z83
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CK2 ALPHA BOUND TO CHEMICAL PROBE SGC-CK2-1
Descriptor:Casein kinase II subunit alpha, SULFATE ION, ~{N}-[5-[[3-cyano-7-(cyclopropylamino)-3~{H}-pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]propanamide, ...
Authors:Kraemer, A., Wells, C., Drewry, D.H., Pickett, J.E., Axtman, A.D., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2020-06-02
Release date:2020-07-29
Method:X-RAY DIFFRACTION (2.171 Å)
Cite:CK2 alpha bound to chemical probe SGC-CK2-1
To Be Published
6Z84
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CK2 ALPHA BOUND TO CHEMICAL PROBE SGC-CK2-1 DERIVATIVE
Descriptor:Casein kinase II subunit alpha, SULFATE ION, ~{N}-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]ethanamide
Authors:Kraemer, A., Wells, C., Drewry, D.H., Pickett, J.E., Axtman, A.D., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2020-06-02
Release date:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:CK2 alpha bound to chemical probe SGC-CK2-1
To Be Published
167327
PDB entries from 2020-08-05