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6K0A
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CRYO-EM STRUCTURE OF AN ARCHAEAL RIBONUCLEASE P
Descriptor:Ribonuclease P protein component 2, Ribonuclease P protein component 3, Ribonuclease P protein component 1, ...
Authors:Wan, F., Lan, P., Wu, J., Lei, M.
Deposit date:2019-05-05
Release date:2019-06-19
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Nat Commun, 10, 2019
6K0B
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CRYO-EM STRUCTURE OF ARCHAEAL RIBONUCLEASE P WITH MATURE TRNA
Descriptor:Ribonuclease P protein component 2, Ribonuclease P protein component 3, Ribonuclease P protein component 1, ...
Authors:Wan, F., Lan, P., Wu, J., Lei, M.
Deposit date:2019-05-05
Release date:2019-06-19
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Nat Commun, 10, 2019
6OUO
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RF2 ACCOMMODATED STATE BOUND 70S COMPLEX AT LONG INCUBATION TIME
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-05
Release date:2019-06-19
Last modified:2019-06-26
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OUT
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ASYMMETRIC FOCUSED RECONSTRUCTION OF HUMAN NOROVIRUS GI.1 NORWALK STRAIN VLP ASYMMETRIC UNIT IN T=3 SYMMETRY
Descriptor:Capsid protein VP1
Authors:Jung, J., Grant, T., Thomas, D.R., Diehnelt, C.W., Grigorieff, N., Joshua-Tor, L.
Deposit date:2019-05-05
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OUU
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SYMMETRIC RECONSTRUCTION OF HUMAN NOROVIRUS GII.4 MINERVA STRAIN VLP IN T=4 SYMMETRY
Descriptor:Major capsid protein
Authors:Jung, J., Grant, T., Thomas, D.R., Diehnelt, C.W., Grigorieff, N., Joshua-Tor, L.
Deposit date:2019-05-05
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OUV
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1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE (DXPS) FROM DEINOCOCCUS RADIODURANS WITH METHYLACETYLPHOSPHONATE (MAP) BOUND
Descriptor:1-deoxy-D-xylulose-5-phosphate synthase, 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, MAGNESIUM ION, ...
Authors:Chen, P.Y.-T., Drennan, C.L.
Deposit date:2019-05-05
Release date:2019-07-03
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (1.937 Å)
Cite:X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1‐deoxy‐d‐xylulose 5-phosphate synthase reaction coordinate.
J.Biol.Chem., 2019
6OUW
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1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE (DXPS) FROM DEINOCOCCUS RADIODURANS WITH ENAMINE INTERMEDIATE BOUND
Descriptor:1-deoxy-D-xylulose-5-phosphate synthase, 2-ACETYL-THIAMINE DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chen, P.Y.-T., Drennan, C.L.
Deposit date:2019-05-05
Release date:2019-07-03
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1‐deoxy‐d‐xylulose 5-phosphate synthase reaction coordinate.
J.Biol.Chem., 2019
6OUX
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STRUCTURE OF SMUL_1544, A DECARBOXYLASE FROM SULFUROSPIRILLUM MULTIVORANS
Descriptor:Threonine phosphate decarboxylase-like enzyme
Authors:Wetterhorn, K.M., Rayment, I., Vecellio, A., Seeger, M., Keller, S., Schubert, T.
Deposit date:2019-05-05
Release date:2019-06-05
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural and functional analysis of an L-serine O-phosphate decarboxylase involved in norcobamide biosynthesis
To Be Published
6RM3
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EVOLUTIONARY COMPACTION AND ADAPTATION VISUALIZED BY THE STRUCTURE OF THE DORMANT MICROSPORIDIAN RIBOSOME
Descriptor:16S rRNA, 5S rRNA, uL2, ...
Authors:Barandun, J., Hunziker, M., Vossbrinck, C.R., Klinge, S.
Deposit date:2019-05-05
Release date:2019-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome
Nat Microbiol, 2019
6OU9
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ASYMMETRIC FOCUSED RECONSTRUCTION OF HUMAN NOROVIRUS GI.7 HOUSTON STRAIN VLP ASYMMETRIC UNIT IN T=3 SYMMETRY
Descriptor:Major capsid protein
Authors:Jung, J., Grant, T., Thomas, D.R., Diehnelt, C.W., Grigorieff, N., Joshua-Tor, L.
Deposit date:2019-05-04
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OUA
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CRYO-EM STRUCTURE OF THE YEAST CTF3 COMPLEX
Descriptor:Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, Inner kinetochore subunit MCM22
Authors:Hinshaw, S.M., Harrison, S.C.
Deposit date:2019-05-04
Release date:2019-05-15
Last modified:2019-06-26
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:The structure of the yeast Ctf3 complex.
Elife, 8, 2019
6OUC
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ASYMMETRIC FOCSUED RECONSTRUCTION OF HUMAN NOROVIRUS GII.2 SNOW MOUNTAIN VIRUS STRAIN VLP ASYMMETRIC UNIT IN T=1 SYMMETRY
Descriptor:Viral protein 1, ZINC ION
Authors:Jung, J., Grant, T., Thomas, D.R., Diehnelt, C.W., Grigorieff, N., Joshua-Tor, L.
Deposit date:2019-05-04
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
6JZR
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STRUCTURE OF THE BACTERIAL FLAGELLAR POLYROD
Descriptor:Flagellar basal-body rod protein FlgG
Authors:Saijo-Hamano, Y., Matsunami, H., Namba, K., Imada, K.
Deposit date:2019-05-03
Release date:2019-07-17
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Architecture of the Bacterial Flagellar Distal Rod and Hook of Salmonella
Biomolecules, 9, 2019
6JZT
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STRUCTURE OF THE BACTERIAL FLAGELLAR HOOK FROM SALMONELLA TYPHIMURIUM
Descriptor:Flagellar hook protein FlgE
Authors:Saijo-Hamano, Y., Matsunami, H., Namba, K., Imada, K.
Deposit date:2019-05-03
Release date:2019-07-17
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Architecture of the Bacterial Flagellar Distal Rod and Hook of Salmonella
Biomolecules, 9, 2019
6OTE
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CRYSTAL STRUCTURE OF SERYL-TRNA SYNTHETASE (SERRS) FROM CRYPTOSPORIDIUM PARVUM COMPLEXED WITH L-SERYLSULFAMOYL ADENOSINE
Descriptor:Seryl-tRNA synthetase, cytoplasmic, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-05-03
Release date:2019-05-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structure of Seryl-tRNA synthetase (SerRS) from Cryptosporidium parvum complexed with L-Serylsulfamoyl Adenosine
to be published
6OTF
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SYMMETRIC RECONSTRUCTION OF HUMAN NOROVIRUS GII.2 SNOW MOUNTAIN VIRUS STRAIN VLP IN T=3 SYMMETRY
Descriptor:Viral protein 1, ZINC ION
Authors:Jung, J., Grant, T., Thomas, D.R., Diehnelt, C.W., Grigorieff, N., Joshua-Tor, L.
Deposit date:2019-05-03
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OTG
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HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH GRL-011-11A (A METHYLAMINE BIS-TETRAHYDROFURAN P2-LIGAND, SULFONAMIDE ISOSTERE DERIVATE)
Descriptor:Protease, FORMIC ACID, (3R,3aS,4R,6aR)-4-(methylamino)hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, ...
Authors:Wang, Y.-F., Pawar, S., Weber, I.T.
Deposit date:2019-05-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural studies of antiviral inhibitor with HIV-1 protease bearing drug resistant substitutions of V32I, I47V and V82I.
Biochem.Biophys.Res.Commun., 514, 2019
6OTJ
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CRYSTAL STRUCTURE OF TYROSYL-TRNA SYNTHETASE FROM NEISSERIA GONORRHOEAE WITH BOUND L-TYR
Descriptor:Tyrosine--tRNA ligase, TYROSINE, SULFATE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-05-03
Release date:2019-05-15
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of Tyrosyl-tRNA synthetase from Neisseria gonorrhoeae with bound L-Tyr
to be published
6OTL
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STRUCTURE OF AEDES AEGYPTI OBP22 IN THE COMPLEX WITH BENZALDEHYDE
Descriptor:AAEL005772-PA, HEXATANTALUM DODECABROMIDE, BENZOIC ACID, ...
Authors:Jones, D.N., Murphy, E.
Deposit date:2019-05-03
Release date:2019-06-12
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure of Aedes aegypti OBP22 in the complex with benzaldehyde
To Be Published
6OTS
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RAT ERK2 E320K
Descriptor:Mitogen-activated protein kinase 1
Authors:Taylor, C.A., Cormier, K.W., Juang, Y.-C., Goldsmith, E.J., Cobb, M.H.
Deposit date:2019-05-03
Release date:2019-07-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional divergence caused by mutations in an energetic hotspot in ERK2
Proc.Natl.Acad.Sci.USA, 2019
6OTU
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CRYSTAL STRUCTURE OF A GLUCOSE-6-PHOSPHATE ISOMERASE FROM CHLAMYDIA TRACHOMATIS D/UW-3/CX
Descriptor:Glucose-6-phosphate isomerase, ACETATE ION, GLUCOSE-6-PHOSPHATE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-05-03
Release date:2019-05-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of a glucose-6-phosphate isomerase from Chlamydia trachomatis D/UW-3/Cx
To Be Published
6OTV
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CRYSTAL STRUCTURE OF PUTATIVE ISOMERASE EC2056
Descriptor:Putative isomerase YbhH, ACETATE ION, 1,2-ETHANEDIOL, ...
Authors:Chang, C., Evdokimova, E., Savchenko, A., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-05-03
Release date:2019-05-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of putative isomerase EC2056
To Be Published
6OU0
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CRYSTAL STRUCTURE OF THE D380A/D478S VARIANT OF THE MYOCILIN OLFACTOMEDIN DOMAIN
Descriptor:Myocilin, GLYCEROL
Authors:Hill, S.E., Kwon, M.S., Lieberman, R.L.
Deposit date:2019-05-03
Release date:2019-07-03
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Calcium-depleted variants of the myocilin olfactomedin domain reveal a stable alternative conformation with an unwound helix
To Be Published
6OU1
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CRYSTAL STRUCTURE OF THE COMPUTATIONALLY-DERIVED 21-VARIANT OF THE MYOCILIN OLFACTOMEDIN DOMAIN
Descriptor:Myocilin, CALCIUM ION, SODIUM ION, ...
Authors:Hill, S.E., Kwon, M.S., Lieberman, R.L.
Deposit date:2019-05-03
Release date:2019-07-03
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (1.878 Å)
Cite:Calcium-depleted variants of the myocilin olfactomedin domain reveal a stable alternative conformation with an unwound helix
To Be Published
6OU2
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CRYSTAL STRUCTURE OF THE D478N VARIANT OF THE MYOCILIN OLFACTOMEDIN DOMAIN
Descriptor:Myocilin, SODIUM ION, GLYCEROL
Authors:Hill, S.E., Kwon, M.S., Lieberman, R.L.
Deposit date:2019-05-03
Release date:2019-07-03
Method:X-RAY DIFFRACTION (1.963 Å)
Cite:Calcium-depleted variants of the myocilin olfactoctomedin domain reveal a stable alternative conformation with an unwound helix
To Be Published