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6U5T
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ELECTRON CRYOMICROSCOPY STRUCTURE OF S. CEREVISIAE FAS IN THE APO STATE
Descriptor:Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, 4'-PHOSPHOPANTETHEINE, ...
Authors:Lou, J.W., Mazhab-Jafari, M.T.
Deposit date:2019-08-28
Release date:2019-10-16
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
6U5U
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ELECTRON CRYOMICROSCOPY STRUCTURE OF S. CEREVISIAE FAS IN THE KS-STALLED STATE
Descriptor:Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Lou, J.W., Mazhab-Jafari, M.T.
Deposit date:2019-08-28
Release date:2019-10-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
6U5V
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ELECTRON CRYOMICROSCOPY STRUCTURE OF C. ALBICANS FAS IN THE APO STATE
Descriptor:Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, 4'-PHOSPHOPANTETHEINE, ...
Authors:Lou, J.W., Mazhab-Jafari, M.T.
Deposit date:2019-08-28
Release date:2019-10-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
6U5W
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ELECTRON CRYOMICROSCOPY STRUCTURE OF C. ALBICANS FAS IN THE KS-STALLED STATE
Descriptor:Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Lou, J.W., Mazhab-Jafari, M.T.
Deposit date:2019-08-28
Release date:2019-10-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase.
Sci Rep, 9, 2019
6U60
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CRYSTAL STRUCTURE OF PREPHENATE DEHYDROGENASE TYRA FROM BACILLUS ANTHRACIS IN COMPLEX WITH NAD AND L-TYROSINE
Descriptor:Prephenate dehydrogenase, TYROSINE, PHOSPHATE ION, ...
Authors:Shabalin, I.G., Hou, J., Kutner, J., Grimshaw, S., Christendat, D., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-08-28
Release date:2019-09-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of Bacillus anthracis prephenate dehydrogenase identified an ACT regulatory domain and a novel mode of metabolic regulation for proteins within the prephenate dehydrogenase family of enzyme
to be published
6SNU
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CRYSTAL STRUCTURE OF THE W60C MUTANT OF THE (S)-SELECTIVE TRANSAMINASE FROM CHROMOBACTERIUM VIOLACEUM
Descriptor:Aspartate aminotransferase family protein, 1,2-ETHANEDIOL, PYRIDOXAL-5'-PHOSPHATE
Authors:Ruggieri, F., Gustafsson, C., Kimbung, R.Y., Walse, B., Logan, D.T., Berglund, P.
Deposit date:2019-08-27
Release date:2019-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures Combined with Molecular Dynamics Reveal Altered Flow of Water in the Active Site of W60C Chromobacterium violaceum omega-transaminase
To Be Published
6SNY
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SYNTHETIC MIMIC OF AN EPCR-BINDING PFEMP1 BOUND TO EPCR
Descriptor:Synthetic EPCR binding protein, Endothelial protein C receptor, PHOSPHATIDYLETHANOLAMINE, ...
Authors:Barber, N.M., Higgins, M.K.
Deposit date:2019-08-27
Release date:2019-09-04
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Structure-guided design of a synthetic mimic of an EPCR-binding PfEMP1 protein
To Be Published
6U5A
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CRYSTAL STRUCTURE OF EQUINE SERUM ALBUMIN COMPLEX WITH 6-MNA
Descriptor:Serum albumin, UNKNOWN ATOM OR ION, (6-methoxynaphthalen-2-yl)acetic acid, ...
Authors:Czub, M.P., Handing, K.B., Venkataramany, B.S., Cymborowski, M.T., Shabalin, I.G., Satchell, K.J., Joachimiak, A., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-08-27
Release date:2019-09-04
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of Equine Serum Albumin complex with 6-MNA
To Be Published
6U4M
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SOLUTION STRUCTURE OF PAXILLIN LIM4
Descriptor:Paxillin, ZINC ION
Authors:Zhu, L., Qin, J.
Deposit date:2019-08-26
Release date:2019-10-23
Last modified:2019-11-20
Method:SOLUTION NMR
Cite:Structural Basis of Paxillin Recruitment by Kindlin-2 in Regulating Cell Adhesion.
Structure, 27, 2019
6U4N
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SOLUTION STRUCTURE OF PAXILLIN LIM4 IN COMPLEX WITH KINDLIN-2 F0
Descriptor:Fermitin family homolog 2, Paxillin, ZINC ION
Authors:Zhu, L., Qin, J.
Deposit date:2019-08-26
Release date:2019-10-23
Last modified:2019-11-20
Method:SOLUTION NMR
Cite:Structural Basis of Paxillin Recruitment by Kindlin-2 in Regulating Cell Adhesion.
Structure, 27, 2019
6U4R
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CRYSTAL STRUCTURE OF EQUINE SERUM ALBUMIN COMPLEX WITH KETOPROFEN
Descriptor:Serum albumin, (2S)-2-[3-(benzenecarbonyl)phenyl]propanoic acid, nonanoic acid, ...
Authors:Czub, M.P., Handing, K.B., Shabalin, I.G., Satchell, K.J., Joachimiak, A., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-08-26
Release date:2019-09-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of Equine Serum Albumin complex with ketoprofen
To Be Published
6U4X
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CRYSTAL STRUCTURE OF EQUINE SERUM ALBUMIN COMPLEX WITH IBUPROFEN
Descriptor:Serum albumin, UNKNOWN LIGAND, UNKNOWN ATOM OR ION, ...
Authors:Czub, M.P., Handing, K.B., Venkataramany, B.S., Steen, E.H., Shabalin, I.G., Satchell, K.J., Joachimiak, A., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-08-26
Release date:2019-09-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of Equine Serum Albumin complex with ibuprofen
To Be Published
6U50
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ANTI-SUDAN EBOLAVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY SUDAN B (SB)
Descriptor:Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB), (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Taylor, A.B., Sherwood, L.J., Hart, P.J., Hayhurst, A.
Deposit date:2019-08-26
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Paratope duality and gullying are among the atypical recognition mechanisms employed by a trio of nanobodies to differentiate ebolavirus nucleoproteins.
J.Mol.Biol., 2019
6U51
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ANTI-SUDAN EBOLAVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY SUDAN B (SB) COMPLEXED WITH SUDAN EBOLAVIRUS NUCLEOPROTEIN C-TERMINAL DOMAIN 610-738
Descriptor:Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB), Nucleoprotein
Authors:Taylor, A.B., Sherwood, L.J., Hart, P.J., Hayhurst, A.
Deposit date:2019-08-26
Release date:2019-11-06
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Paratope duality and gullying are among the atypical recognition mechanisms employed by a trio of nanobodies to differentiate ebolavirus nucleoproteins.
J.Mol.Biol., 2019
6U52
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ANTI-SUDAN EBOLAVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY SUDAN B (SB) COMPLEXED WITH SUDAN EBOLAVIRUS NUCLEOPROTEIN C-TERMINAL DOMAIN 634-738
Descriptor:Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB), Nucleoprotein, CHLORIDE ION
Authors:Taylor, A.B., Sherwood, L.J., Hart, P.J., Hayhurst, A.
Deposit date:2019-08-26
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Paratope duality and gullying are among the atypical recognition mechanisms employed by a trio of nanobodies to differentiate ebolavirus nucleoproteins.
J.Mol.Biol., 2019
6U53
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ANTI-ZAIRE EBOLAVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY ZAIRE C (ZC)
Descriptor:Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire C (ZC)
Authors:Taylor, A.B., Sherwood, L.J., Hart, P.J., Hayhurst, A.
Deposit date:2019-08-26
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Paratope duality and gullying are among the atypical recognition mechanisms employed by a trio of nanobodies to differentiate ebolavirus nucleoproteins.
J.Mol.Biol., 2019
6U54
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ANTI-ZAIRE EBOLAVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY ZAIRE C (ZC) COMPLEXED WITH ZAIRE EBOLAVIRUS NUCLEOPROTEIN C-TERMINAL DOMAIN 634-739
Descriptor:Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire C (ZC), Nucleoprotein
Authors:Taylor, A.B., Sherwood, L.J., Hart, P.J., Hayhurst, A.
Deposit date:2019-08-26
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Paratope duality and gullying are among the atypical recognition mechanisms employed by a trio of nanobodies to differentiate ebolavirus nucleoproteins.
J.Mol.Biol., 2019
6U55
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ANTI-ZAIRE EBOLAVIRUS NUCLEOPROTEIN SINGLE DOMAIN ANTIBODY ZAIRE E (ZE) COMPLEXED WITH SUDAN EBOLAVIRUS NUCLEOPROTEIN C-TERMINAL DOMAIN 634-738
Descriptor:Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire E (ZE), Nucleoprotein
Authors:Taylor, A.B., Sherwood, L.J., Hart, P.J., Hayhurst, A.
Deposit date:2019-08-26
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Paratope duality and gullying are among the atypical recognition mechanisms employed by a trio of nanobodies to differentiate ebolavirus nucleoproteins.
J.Mol.Biol., 2019
6KSN
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STRUCTURE OF A ZN-BOUND CAMELID SINGLE DOMAIN ANTIBODY
Descriptor:ICab3, ZINC ION, 1,2-ETHANEDIOL, ...
Authors:Kumar, S., Athreya, A., Penmatsa, A.
Deposit date:2019-08-24
Release date:2019-11-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Isolation and structural characterization of a Zn2+-bound single-domain antibody against NorC, a putative multi-drug efflux transporter in bacteria.
J.Biol.Chem., 2019
6SNG
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EFEM STRUCTURE FROM THE PSEUDOMONAS SYRINGAE EFEUOB/M IRON-TRANSPORT SYSTEM: A NEW FAMILY OF PERIPLASMIC SOLUTE-BINDING PROTEINS WITH UNIQUE FOLD
Descriptor:Peptidase_M75 domain-containing protein, SULFATE ION
Authors:Watson, K.A., Rajasekaran, M.
Deposit date:2019-08-24
Release date:2019-10-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:EfeM structure from the Pseudomonas syringae EfeUOB/M iron-transport system: a new family of periplasmic solute-binding proteins with unique fold
To Be Published
6KS6
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TRIC AT 0.2 MM ADP-ALFX, CONFORMATION 1, 0.2-C1
Descriptor:T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Jin, M., Cong, Y.
Deposit date:2019-08-23
Release date:2019-09-18
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6KS7
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TRIC AT 0.1 MM ADP-ALFX, CONFORMATION 1, 0.1-C1
Descriptor:T-complex protein 1 subunit eta, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
Authors:Jin, M., Cong, Y.
Deposit date:2019-08-23
Release date:2019-09-18
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.62 Å)
Cite:An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6KS8
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TRIC AT 0.1 MM ADP-ALFX, CONFORMATION 4, 0.1-C4
Descriptor:T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Jin, M., Cong, Y.
Deposit date:2019-08-23
Release date:2019-09-18
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.69 Å)
Cite:An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6SN6
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CARBOXYPEPTIDASE T WITH N-SULFAMOYL-L-GLUTAMIC ACID
Descriptor:Carboxypeptidase T, ZINC ION, N-sulfamoyl-L-glutamic acid, ...
Authors:Timofeev, V.I., Akparov, V.K., Kuranova, I.P.
Deposit date:2019-08-23
Release date:2019-10-09
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:CARBOXYPEPTIDASE T WITH N-SULFAMOYL-L-GLUTAMIC ACID
To Be Published
6SNC
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CRYSTAL STRUCTURE OF LN01 FAB IN COMPLEX WITH AN HIV-1 GP41 PEPTIDE
Descriptor:LNO1 Light Chain, LNO1 Heavy Chain, Envelope glycoprotein gp160, ...
Authors:Caillat, C., Pinto, D., Corti, D., Fenwick, C., Pantaleo, G., Weissenhorn, W.
Deposit date:2019-08-23
Release date:2019-11-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 2019