Mine: Advanced search results

Advanced query:
Add keyword:
Search
Go to Advanced search
6Q1Y
  • Download 6q1y
  • View 6q1y
Molmil generated image of 6q1y
CRYSTAL STRUCTURE OF ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FROM MYCOBACTERIUM AVIUM WITH BOUND NAD
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ACETATE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-08-06
Release date:2019-08-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of Enoyl-[acyl-carrier-protein] reductase from Mycobacterium avium with bound NAD
to be published
6Q10
  • Download 6q10
  • View 6q10
Molmil generated image of 6q10
CRYSTAL STRUCTURE OF THE SOLUBLE DOMAIN (RESIDUES 71-217) OF A CONSERVED HYPOTHETICAL SECRETED PROTEIN (RV2700 ORTHOLOG) FROM MYCOBACTERIUM MARINUM
Descriptor:MymaA.19257.a.B3, 1,2-ETHANEDIOL
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-08-02
Release date:2019-08-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:SSGCID, Mycobacerium marinum, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, secreted protein, Rv2700 ortholog
to be published
6Q12
  • Download 6q12
  • View 6q12
Molmil generated image of 6q12
STRUCTURE OF PRO-ESP MUTANT- S66V
Descriptor:Glutamyl endopeptidase
Authors:Manne, K., Narayana, S.V.L.
Deposit date:2019-08-02
Release date:2019-08-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into the Role of N-Terminus in the Activation and Function of Extracellular Serine Protease of Staphylococcus epidermidis
To Be Published
6PZM
  • Download 6pzm
  • View 6pzm
Molmil generated image of 6pzm
PUTATIVE SDR FROM ACINETOBACTER BAUMANNII CRYSTAL FORM 1
Descriptor:3-ketoacyl-ACP reductase
Authors:Cross, E.M., Aragao, D., Forwood, J.K.
Deposit date:2019-08-01
Release date:2019-08-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of a putative FabG enzyme from multi-drug resistant Acinetobacter baumannii
To Be Published
6PZN
  • Download 6pzn
  • View 6pzn
Molmil generated image of 6pzn
PUTATIVE SDR FROM ACINETOBACTER BAUMANNII CRYSTAL FORM 2
Descriptor:3-ketoacyl-ACP reductase
Authors:Cross, E.M., Aragao, D., Forwood, J.K.
Deposit date:2019-08-01
Release date:2019-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterization of a putative FabG enzyme from multi-drug resistant Acinetobacter baumannii
To Be Published
6PZ9
  • Download 6pz9
  • View 6pz9
Molmil generated image of 6pz9
CRYO-EM STRUCTURE OF THE PANCREATIC BETA-CELL SUR1 BOUND TO ATP AND REPAGLINIDE
Descriptor:ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, Repaglinide, ...
Authors:Shyng, S.L., Yoshioka, C., Martin, G.M., Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian KATPchannel revealed by cryo-EM.
Elife, 8, 2019
6PZA
  • Download 6pza
  • View 6pza
Molmil generated image of 6pza
CRYO-EM STRUCTURE OF THE PANCREATIC BETA-CELL SUR1 BOUND TO ATP AND GLIBENCLAMIDE
Descriptor:ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ...
Authors:Shyng, S.L., Yoshioka, C., Martin, G.M., Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian KATPchannel revealed by cryo-EM.
Elife, 8, 2019
6PZB
  • Download 6pzb
  • View 6pzb
Molmil generated image of 6pzb
CRYO-EM STRUCTURE OF THE PANCREATIC BETA-CELL SUR1 APO STATE
Descriptor:ATP-binding cassette sub-family C member 8
Authors:Shyng, S.L., Yoshioka, C., Martin, G.M., Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian KATPchannel revealed by cryo-EM.
Elife, 8, 2019
6PZC
  • Download 6pzc
  • View 6pzc
Molmil generated image of 6pzc
CRYO-EM STRUCTURE OF THE PANCREATIC BETA-CELL SUR1 BOUND TO CARBAMAZEPINE
Descriptor:ATP-binding cassette sub-family C member 8
Authors:Shyng, S.L., Yoshioka, C., Martin, G.M., Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian KATPchannel revealed by cryo-EM.
Elife, 8, 2019
6PZI
  • Download 6pzi
  • View 6pzi
Molmil generated image of 6pzi
CRYO-EM STRUCTURE OF THE PANCREATIC BETA-CELL SUR1 BOUND TO ATP ONLY
Descriptor:ATP-binding cassette sub-family C member 8, ADENOSINE-5'-TRIPHOSPHATE
Authors:Shyng, S.L., Yoshioka, C., Martin, G.M., Sung, M.W.
Deposit date:2019-07-31
Release date:2019-08-14
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Mechanism of pharmacochaperoning in a mammalian KATPchannel revealed by cryo-EM.
Elife, 8, 2019
6PZJ
  • Download 6pzj
  • View 6pzj
Molmil generated image of 6pzj
STRUCTURE OF THE N-TERMINAL DOMAIN (RESIDUES 43-304) OF METHYL-ACCEPTING CHEMOTAXIS PROTEIN FROM LEPTOSPIRA INTERROGANS SEROGROUP ICTEROHAEMORRHAGIAE SEROVAR COPENHAGENI (STRAIN FIOCRUZ L1-130)
Descriptor:Methyl-accepting chemotaxis protein, CHLORIDE ION, 1,2-ETHANEDIOL
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-07-31
Release date:2019-08-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of the N-terminal domain (residues 43-304) of Methyl-accepting chemotaxis protein from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Copenhageni (strain Fiocruz L1-130)
to be published
6PYM
  • Download 6pym
  • View 6pym
Molmil generated image of 6pym
STRUCTURE OF ACTIVE-SITE SERINE MUTANT OF ESP, SERINE PROTEASE FROM STAPHYLOCOCCUS EPIDERMIDIS
Descriptor:Glutamyl endopeptidase
Authors:Manne, K., Narayana, S.V.L.
Deposit date:2019-07-30
Release date:2019-08-14
Method:X-RAY DIFFRACTION (1.200018 Å)
Cite:Structural Insights into the Role of N-Terminus in the Activation and Function of Extracellular Serine Protease of Staphylococcus epidermidis
To Be Published
6SEG
  • Download 6seg
  • View 6seg
Molmil generated image of 6seg
CLASS1: CENP-A NUCLEOSOME IN COMPLEX WITH CENP-C CENTRAL REGION
Descriptor:Histone H3-like centromeric protein A, Histone H4, Histone H2A type 2-A, ...
Authors:Ali-Ahmad, A., Bilokapic, S., Schafer, I.B., Halic, M., Sekulic, N.
Deposit date:2019-07-30
Release date:2019-08-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:CryoEM structure of human CENP-A nucleosome alone and in complex with central domain of human CENP-C
To Be Published
6KL8
  • Download 6kl8
  • View 6kl8
Molmil generated image of 6kl8
CRYSTAL STRUCTURE OF PIPTIDYL T-RNA HYDROLASE FROM ACINETOBACTER BAUMANNII WITH BOUND NACL AT THE SUBSTRATE BINDING SITE
Descriptor:Peptidyl-tRNA hydrolase, CHLORIDE ION, SODIUM ION, ...
Authors:Viswanathan, V., Sharma, P., Singh, P.K., Sharma, S., Singh, T.P.
Deposit date:2019-07-29
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal structure of Piptidyl t-RNA hydrolase from Acinetobacter baumannii with bound NaCl at the substrate binding site
To Be Published
6PY8
  • Download 6py8
  • View 6py8
Molmil generated image of 6py8
CRYSTAL STRUCTURE OF THE RBPJ-NOTCH1-NRARP TERNARY COMPLEX BOUND TO DNA
Descriptor:Notch-regulated ankyrin repeat-containing protein, DNA, Recombining binding protein suppressor of hairless, ...
Authors:Jarrett, S.M., Seegar, T.C.M., Blacklow, S.C.
Deposit date:2019-07-29
Release date:2019-08-14
Method:X-RAY DIFFRACTION (3.754 Å)
Cite:Molecular basis for feedback inhibition of Notch signaling by the Notch regulated ankyrin repeat protein NRARP
To Be Published
6SE0
  • Download 6se0
  • View 6se0
Molmil generated image of 6se0
CLASS 1 : CENP-A NUCLEOSOME
Descriptor:Histone H3-like centromeric protein A, Histone H4, Histone H2A type 2-A, ...
Authors:Ali-Ahmad, A., Bilokapic, S., Schafer, I.B., Halic, M., Sekulic, N.
Deposit date:2019-07-29
Release date:2019-08-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:CENP-C unwraps the CENP-A nucleosome through the H2A C-terminal tail
To Be Published
6SE4
  • Download 6se4
  • View 6se4
Molmil generated image of 6se4
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH (+)-JD1, AN ORGANOMETALLIC BET BROMODOMAIN INHIBITOR
Descriptor:Bromodomain-containing protein 4, 1,2-ETHANEDIOL, (+)-JD1, ...
Authors:Krojer, T., Hassell-Hart, S., Picaud, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Filippakopoulos, P., Spencer, J., von Delft, F., Structural Genomics Consortium (SGC)
Deposit date:2019-07-29
Release date:2019-08-14
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Crystal Structure of the first bromodomain of human BRD4 in complex with (+)-JD1, an Organometallic BET Bromodomain Inhibitor
To Be Published
6SE6
  • Download 6se6
  • View 6se6
Molmil generated image of 6se6
CLASS2 : CENP-A NUCLEOSOME IN COMPLEX WITH CENP-C CENTRAL REGION
Descriptor:Histone H3-like centromeric protein A, Histone H4, Histone H2A type 2-A, ...
Authors:Ali-Ahmad, A., Bilokapic, S., Schafer, I.B., Halic, M., Sekulic, N.
Deposit date:2019-07-29
Release date:2019-08-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:CENP-C unwraps the CENP-A nucleosome through the H2A C-terminal tail
To Be Published
6SEE
  • Download 6see
  • View 6see
Molmil generated image of 6see
CLASS2A : CENP-A NUCLEOSOME IN COMPLEX WITH CENP-C CENTRAL REGION
Descriptor:Histone H3-like centromeric protein A, Histone H4, Histone H2A type 2-A, ...
Authors:Ali-Ahmad, A., Bilokapic, S., Schafer, I.B., Halic, M., Sekulic, N.
Deposit date:2019-07-29
Release date:2019-08-14
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:CENP-C unwraps the CENP-A nucleosome through the H2A C-terminal tail
To Be Published
6SEF
  • Download 6sef
  • View 6sef
Molmil generated image of 6sef
CLASS2C : CENP-A NUCLEOSOME IN COMPLEX WITH CENP-C CENTRAL REGION
Descriptor:Histone H3-like centromeric protein A, Histone H4, Histone H2A type 2-A, ...
Authors:Ali-Ahmad, A., Bilokapic, S., Schafer, I.B., Halic, M., Sekulic, N.
Deposit date:2019-07-29
Release date:2019-08-14
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:CryoEM structure of human CENP-A nucleosome alone and in complex with central domain of human CENP-C
To Be Published
6PXM
  • Download 6pxm
  • View 6pxm
Molmil generated image of 6pxm
HORSE SPLEEN APOFERRITIN LIGHT CHAIN
Descriptor:Ferritin light chain
Authors:Kopylov, M., Kelley, K., Yen, L.Y., Rice, W.J., Eng, E.T., Carragher, B., Potter, C.S.
Deposit date:2019-07-26
Release date:2019-08-07
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Horse spleen apoferritin light chain structure at 2.1 Angstrom resolution
To Be Published
6SD9
  • Download 6sd9
  • View 6sd9
Molmil generated image of 6sd9
CRYSTAL STRUCTURE OF WILD-TYPE CMET BOUND BY FORETINIB
Descriptor:Hepatocyte growth factor receptor, CHLORIDE ION, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Authors:Collie, G.W., Phillips, C.
Deposit date:2019-07-26
Release date:2019-08-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and molecular insight into resistance mechanisms of first generation cMET inhibitors
Acs Med.Chem.Lett., 2019
6SDC
  • Download 6sdc
  • View 6sdc
Molmil generated image of 6sdc
CRYSTAL STRUCTURE OF D1228V CMET BOUND BY FORETINIB
Descriptor:Hepatocyte growth factor receptor, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Authors:Collie, G.W., Phillips, C.
Deposit date:2019-07-26
Release date:2019-08-14
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural and molecular insight into resistance mechanisms of first generation cMET inhibitors
Acs Med.Chem.Lett., 2019
6SDD
  • Download 6sdd
  • View 6sdd
Molmil generated image of 6sdd
CRYSTAL STRUCTURE OF D1228V CMET BOUND BY BMS-777607
Descriptor:Hepatocyte growth factor receptor, N-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl}-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide, GLYCEROL
Authors:Collie, G.W., Phillips, C.
Deposit date:2019-07-26
Release date:2019-08-14
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural and molecular insight into resistance mechanisms of first generation cMET inhibitors
Acs Med.Chem.Lett., 2019
6SDE
  • Download 6sde
  • View 6sde
Molmil generated image of 6sde
CRYSTAL STRUCTURE OF WILD-TYPE CMET BOUND BY SAVOLITINIB
Descriptor:Hepatocyte growth factor receptor, volitinib
Authors:Collie, G.W., Phillips, C.
Deposit date:2019-07-26
Release date:2019-08-14
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural and molecular insight into resistance mechanisms of first generation cMET inhibitors
Acs Med.Chem.Lett., 2019