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6O5N
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TUBULIN-RB3_SLD-TTL IN COMPLEX WITH COMPOUND 10AB
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Kumar, G., Wang, Y., Li, W., White, S.W.
Deposit date:2019-03-04
Release date:2019-07-10
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Structure guided design, synthesis, and biological evaluation of 2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) analogs targeting the colchicine binding site in tubulin.
J.Med.Chem., 2019
6O61
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TUBULIN-RB3_SLD-TTL IN COMPLEX WITH COMPOUND ABI-231
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Kumar, G., Wang, Y., Li, W., White, S.W.
Deposit date:2019-03-05
Release date:2019-07-10
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:Structure guided design, synthesis, and biological evaluation of 2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) analogs targeting the colchicine binding site in tubulin.
J.Med.Chem., 2019
6OE9
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CRYSTAL STRUCTURE OF P204 HIN1 DOMAIN
Descriptor:Interferon-activable protein 204, GLYCEROL, SULFATE ION
Authors:Tian, Y., Yin, Q.
Deposit date:2019-03-27
Release date:2019-07-10
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural analysis of the HIN1 domain of interferon-inducible protein 204.
Acta Crystallogr.,Sect.F, 75, 2019
6OFE
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HELICAL RECONSTRUCTION OF TYPE III SECRETION SYSTEM NEEDLE FILAMENT MUTANT-PRGI S49A
Descriptor:Protein PrgI
Authors:Guo, E.Z., Galan, J.E.
Deposit date:2019-03-29
Release date:2019-07-10
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion.
Plos Biol., 17, 2019
6OFF
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HIGH-RESOLUTION FILAMENTOUS STRUCTURES OF IN VITRO POLYMERIZED PRGI NEEDLE
Descriptor:Protein PrgI
Authors:Guo, E.Z., Galan, J.E.
Deposit date:2019-03-29
Release date:2019-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion.
Plos Biol., 17, 2019
6OFG
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IN VITRO POLYMERIZED PRGI V67A FILAMENTS
Descriptor:Protein PrgI
Authors:Guo, E.Z., Galan, J.E.
Deposit date:2019-03-29
Release date:2019-07-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion.
Plos Biol., 17, 2019
6OFH
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STRUCTURE OF SALMONELLA TYPE III SECRETION SYSTEM NEEDLE FILAMENT
Descriptor:Protein PrgI
Authors:Guo, E.Z., Galan, J.E.
Deposit date:2019-03-29
Release date:2019-07-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion.
Plos Biol., 17, 2019
6OFK
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CRYSTAL STRUCTURE OF GREEN FLUORESCENT PROTEIN (GFP); S65T; IH CIRCULAR PERMUTANT (50-51)
Descriptor:Green Fluorescent Protein (GFP); S65T; ih circular permutant (50-51), {2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid, ACETATE ION
Authors:Lin, C.-Y., Romei, M.G., Mathews, I.I., Boxer, S.G.
Deposit date:2019-03-30
Release date:2019-07-10
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal structure of green fluorescent protein (GFP); S65T; ih circular permutant (50-51)
To Be Published
6OFL
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CRYSTAL STRUCTURE OF GREEN FLUORESCENT PROTEIN (GFP); S65T, Y66(3-CLY); IH CIRCULAR PERMUTANT (50-51)
Descriptor:Green fluorescent protein (GFP); S65T, Y66(3-ClY); ih circular permutant (50-51)
Authors:Lin, C.-Y., Romei, M.G., Mathews, I.I., Boxer, S.G.
Deposit date:2019-03-31
Release date:2019-07-10
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal structure of green fluorescent protein (GFP); S65T, Y66(3-ClY); ih circular permutant (50-51)
To Be Published
6OFM
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CRYSTAL STRUCTURE OF GREEN FLUORESCENT PROTEIN (GFP); S65T, Y66(3-CH3Y); IH CIRCULAR PERMUTANT (50-51)
Descriptor:Green fluorescent protein (GFP); S65T, Y66(3-CH3Y); ih circular permutant (50-51)
Authors:Lin, C.-Y., Romei, M.G., Mathews, I.I., Boxer, S.G.
Deposit date:2019-03-31
Release date:2019-07-10
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structure of green fluorescent protein (GFP); S65T, Y66(3-CH3Y); ih circular permutant (50-51)
To Be Published
6OFN
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CRYSTAL STRUCTURE OF GREEN FLUORESCENT PROTEIN (GFP); S65T, T203(3-OMEY); IH CIRCULAR PERMUTANT (50-51)
Descriptor:Green fluorescent protein (GFP); S65T, T203(3-OMeY); ih circular permutant (50-51)
Authors:Lin, C.-Y., Romei, M.G., Mathews, I.I., Boxer, S.G.
Deposit date:2019-03-31
Release date:2019-07-10
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:Crystal structure of green fluorescent protein (GFP); S65T, T203(3-OMeY); ih circular permutant (50-51)
To Be Published
6OFO
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CRYSTAL STRUCTURE OF SPLIT GREEN FLUORESCENT PROTEIN (GFP); S10 CIRCULAR PERMUTANT (194-195)
Descriptor:Green fluorescent protein (GFP); s10 circular permutant (194-195)
Authors:Lin, C.-Y., Romei, M.G., Deller, M.C., Doukov, T.I., Boxer, S.G.
Deposit date:2019-03-31
Release date:2019-07-10
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Crystal structure of split green fluorescent protein (GFP); s10 circular permutant (194-195)
To Be Published
6OGX
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TERNARY COMPLEX OF OX40R (TNFRSF4) BOUND TO FAB1 AND FAB2
Descriptor:Fab 1 Heavy Chain, Fab1 Light Chain, Tumor necrosis factor receptor superfamily member 4, ...
Authors:Ultsch, M.H., Boenig, G., Harris, S.F.
Deposit date:2019-04-03
Release date:2019-07-10
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members.
Mabs, 2019
6OKN
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OX40R (TNFRSF4) BOUND TO FAB 1A7
Descriptor:Fab 1A7 heavy chain, Fab 1A7 light chain, Tumor necrosis factor receptor superfamily member 4, ...
Authors:Ultsch, M.H., Boenig, G., Harris, S.F.
Deposit date:2019-04-14
Release date:2019-07-10
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members.
Mabs, 2019
6OM3
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CRYSTAL STRUCTURE OF THE ORC1 BAH DOMAIN IN COMPLEX WITH A NUCLEOSOME CORE PARTICLE
Descriptor:Histone H3.2, Histone H4, Histone H2A, ...
Authors:De Ioannes, P.E., Wang, M., Armache, K.-J.
Deposit date:2019-04-18
Release date:2019-07-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and function of the Orc1 BAH-nucleosome complex.
Nat Commun, 10, 2019
6OPC
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CDC48 HEXAMER IN A COMPLEX WITH SUBSTRATE AND SHP1(UBX DOMAIN)
Descriptor:Cell division control protein 48, Substrate bound to the central pore of the Cdc48 hexamer, UBX domain-containing protein 1, ...
Authors:Cooney, I., Han, H., Stewart, M., Carson, R.H., Hansen, D., Price, J.C., Hill, C.P., Shen, P.S.
Deposit date:2019-04-24
Release date:2019-07-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the Cdc48 segregase in the act of unfolding an authentic substrate.
Science, 2019
6OQ5
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STRUCTURE OF THE FULL-LENGTH CLOSTRIDIUM DIFFICILE TOXIN B IN COMPLEX WITH 3 VHHS
Descriptor:Toxin B, 5D, E3, ...
Authors:Chen, P., Lam, K., Jin, R.
Deposit date:2019-04-25
Release date:2019-07-10
Method:X-RAY DIFFRACTION (3.87 Å)
Cite:Structure of the full-length Clostridium difficile toxin B
Nat.Struct.Mol.Biol., 2019
6OQ6
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STRUCTURE OF THE PORE FORMING FRAGMENT OF CLOSTRIDIUM DIFFICILE TOXIN B IN COMPLEX WITH VHH 5D
Descriptor:Toxin B, 5D
Authors:Chen, P., Lam, K., Jin, R.
Deposit date:2019-04-25
Release date:2019-07-10
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structure of the full-length Clostridium difficile toxin B
Nat.Struct.Mol.Biol., 2019
6OQ7
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STRUCTURE OF THE GTD DOMAIN OF CLOSTRIDIUM DIFFICILE TOXIN B IN COMPLEX WITH VHH E3
Descriptor:Toxin B, E3, URIDINE-5'-DIPHOSPHATE, ...
Authors:Chen, P., Lam, K., Jin, R.
Deposit date:2019-04-25
Release date:2019-07-10
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of the full-length Clostridium difficile toxin B
Nat.Struct.Mol.Biol., 2019
6OQ8
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STRUCTURE OF THE GTD DOMAIN OF CLOSTRIDIUM DIFFICILE TOXIN B IN COMPLEX WITH VHH 7F
Descriptor:Toxin B, 7F
Authors:Chen, P., Lam, K., Jin, R.
Deposit date:2019-04-25
Release date:2019-07-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the full-length Clostridium difficile toxin B
Nat.Struct.Mol.Biol., 2019
6OR4
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CRYSTAL STRUCTURE OF SPGH29
Descriptor:Glycoside hydrolase, ALPHA-L-FUCOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Pluvinage, B., Boraston, A.B.
Deposit date:2019-04-29
Release date:2019-07-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
J.Biol.Chem., 2019
6ORF
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CRYSTAL STRUCTURE OF SPGH29
Descriptor:SpGH29, ALPHA-L-FUCOSE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Pluvinage, B., Boraston, A.B.
Deposit date:2019-04-30
Release date:2019-07-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
J.Biol.Chem., 2019
6ORG
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CRYSTAL STRUCTURE OF SPGH29
Descriptor:Glycoside hydrolase, CALCIUM ION, 1,2-ETHANEDIOL, ...
Authors:Pluvinage, B., Boraston, A.B.
Deposit date:2019-04-30
Release date:2019-07-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
J.Biol.Chem., 2019
6ORH
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CRYSTAL STRUCTURE OF SPGH29
Descriptor:Glycoside hydrolase, ALPHA-L-FUCOSE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Pluvinage, B., Boraston, A.B.
Deposit date:2019-04-30
Release date:2019-07-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
J.Biol.Chem., 2019
6OS9
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HUMAN NEUROTENSIN RECEPTOR 1 (HNTSR1) - GI1 PROTEIN COMPLEX IN CANONICAL CONFORMATION (C STATE)
Descriptor:Neurotensin receptor type 1, JMV449, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Kato, H.E., Zhang, Y., Kobilka, B.K., Skiniotis, G.
Deposit date:2019-05-01
Release date:2019-07-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational transitions of a neurotensin receptor 1-Gi1complex.
Nature, 2019