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6NJX
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C-TERMINAL REGION OF THE XANTHOMONAS CAMPESTRIS PV. CAMPESTRIS OLD PROTEIN PHASED WITH MERCURY
Descriptor:Xcc_ctr_Hg, MERCURY (II) ION, IODIDE ION
Authors:Schiltz, C.J., Lee, A., Partlow, E.A., Hosford, C.J., Chappie, J.S.
Deposit date:2019-01-04
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage
Nucleic Acids Res., 2019
6NK8
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C-TERMINAL REGION OF THE BURKHOLDERIA PSEUDOMALLEI OLD PROTEIN
Descriptor:Class 2 OLD family nuclease, MAGNESIUM ION
Authors:Schiltz, C.J., Lee, A., Partlow, E.A., Hosford, C.J., Chappie, J.S.
Deposit date:2019-01-05
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage
Nucleic Acids Res., 2019
6NMR
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BLOCKING FAB 119 ANTI-SIRP-ALPHA ANTIBODY IN COMPLEX WITH SIRP-ALPHA VARIANT 1
Descriptor:Fab 119 anti-SIRP-alpha antibody Variable Light Chain, Fab 119 anti-SIRP-alpha antibody Variable Heavy Chain, Tyrosine-protein phosphatase non-receptor type substrate 1
Authors:Wibowo, A.S., Carter, J.J., Sim, J.
Deposit date:2019-01-11
Release date:2019-08-07
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRP alpha.
Mabs, 11, 2019
6NMS
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BLOCKING FAB 136 ANTI-SIRP-ALPHA ANTIBODY IN COMPLEX WITH SIRP-ALPHA VARIANT 1
Descriptor:Fab 136 anti-SIRP-alpha antibody Variable Light Chain, Fab 136 anti-SIRP-alpha antibody Variable Heavy Chain, Tyrosine-protein phosphatase non-receptor type substrate 1
Authors:Wibowo, A.S., Carter, J.J., Sim, J.
Deposit date:2019-01-11
Release date:2019-08-07
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRP alpha.
Mabs, 11, 2019
6NMT
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NON-BLOCKING FAB 3 ANTI-SIRP-ALPHA ANTIBODY IN COMPLEX WITH SIRP-ALPHA VARIANT 1
Descriptor:Fab 3 anti-SIRP-alpha antibody Variable Light Chain, Fab 3 anti-SIRP-alpha antibody Variable Heavy Chain, Tyrosine-protein phosphatase non-receptor type substrate 1
Authors:Wibowo, A.S., Carter, J.J., Sim, J.
Deposit date:2019-01-11
Release date:2019-08-07
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRP alpha.
Mabs, 11, 2019
6NMU
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KICK-OFF FAB 115 ANTI-SIRP-ALPHA ANTIBODY IN COMPLEX WITH SIRP-ALPHA VARIANT 1
Descriptor:Fab 115 anti-SIRP-alpha antibody Variable Light Chain, Fab 115 anti-SIRP-alpha antibody Variable Heavy Chain, Tyrosine-protein phosphatase non-receptor type substrate 1
Authors:Wibowo, A.S., Carter, J.J., Sim, J.
Deposit date:2019-01-11
Release date:2019-08-07
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRP alpha.
Mabs, 11, 2019
6NMV
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NON-BLOCKING FAB 218 ANTI-SIRP-ALPHA ANTIBODY IN COMPLEX WITH SIRP-ALPHA VARIANT 1
Descriptor:Tyrosine-protein phosphatase non-receptor type substrate 1, Fab 218 anti-SIRP-alpha antibody Variable Heavy Chain, Fab 218 anti-SIRP-alpha antibody Variable Light Chain
Authors:Wibowo, A.S., Carter, J.J., Sim, J.
Deposit date:2019-01-11
Release date:2019-08-07
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRP alpha.
Mabs, 11, 2019
6NX6
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ECAII(T89V,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 5
Descriptor:L-asparaginase 2, ACETIC ACID, CITRIC ACID
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NX7
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ECAII(T89V,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 5.6
Descriptor:L-asparaginase 2, ACETIC ACID, CITRIC ACID
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NX8
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ECAII(T89V,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 6.2
Descriptor:L-asparaginase 2, ACETIC ACID, CITRIC ACID
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NX9
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ECAII(T89V,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 7
Descriptor:L-asparaginase 2, ACETIC ACID, IMIDAZOLE, ...
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NXA
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ECAII(T89V,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 7
Descriptor:L-asparaginase 2, ACETIC ACID, GLYCEROL
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NXB
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ECAII IN COMPLEX WITH CITRATE AT PH 7
Descriptor:L-asparaginase 2, CITRIC ACID, GLYCEROL
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NXC
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ECAI(T162A) MUTANT IN COMPLEX WITH CITRATE AT PH 4
Descriptor:L-asparaginase 1, CITRIC ACID, 1,2-ETHANEDIOL, ...
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NXD
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TYPE I L-ASPARAGINASE FROM ESCHERICHIA COLI IN COMPLEX WITH CITRATE AT PH 4
Descriptor:L-asparaginase 1, CHLORIDE ION, CITRIC ACID, ...
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NYA
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CRYSTAL STRUCTURE OF UBIQUITIN E1 (UBA1) IN COMPLEX WITH UBC3 (CDC34) AND UBIQUITIN
Descriptor:Ubiquitin-activating enzyme E1 1, Ubiquitin, Ubiquitin-conjugating enzyme E2-34 kDa, ...
Authors:Olsen, S.K., Williams, K.M., Atkison, J.H.
Deposit date:2019-02-11
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.065 Å)
Cite:Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34.
Nat Commun, 10, 2019
6NYD
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CRYSTAL STRUCTURE OF S. CEREVISIAE UBC3 (CDC34)
Descriptor:Ubiquitin-conjugating enzyme E2-34 kDa, ZINC ION, ACETATE ION
Authors:Olsen, S.K., Williams, K.M., Atkison, J.H.
Deposit date:2019-02-11
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34.
Nat Commun, 10, 2019
6NYO
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CRYSTAL STRUCTURE OF A HUMAN CDC34-UBIQUITIN THIOESTER MIMETIC
Descriptor:Ubiquitin-conjugating enzyme E2 R2, Ubiquitin, 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, ...
Authors:Olsen, S.K., Williams, K.M., Atkison, J.H.
Deposit date:2019-02-11
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34.
Nat Commun, 10, 2019
6O5G
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CALMODULIN IN COMPLEX WITH ISOMALBRANCHEAMIDE D
Descriptor:Calmodulin-1, (5aS,12aS,13aS)-9-bromo-8-chloro-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, CALCIUM ION, ...
Authors:Beyett, T.S., Fraley, A.E., Tesmer, J.J.G.
Deposit date:2019-03-02
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe.
Proc.Natl.Acad.Sci.USA, 2019
6OAF
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SUDAN VIRUS NUCLEOPROTEIN CORE DOMAIN IN COMPLEX WITH VP35 CHAPERONING PEPTIDE
Descriptor:Polymerase cofactor VP35,Nucleoprotein
Authors:Landeras-Bueno, S., Oda, S., Norris, M.J., Li Salie, Z., Ollmann Saphire, E.
Deposit date:2019-03-15
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment.
Mbio, 10, 2019
6OEL
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ENGINEERED FAB BOUND TO IL-4 RECEPTOR
Descriptor:engineered Interleukin-4, RGA variant, Interleukin-4 receptor subunit alpha, ...
Authors:Jude, K.M., Moraga, I., Spangler, J.B., Garcia, K.C.
Deposit date:2019-03-27
Release date:2019-08-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A strategy for the selection of monovalent antibodies that span protein dimer interfaces
J.Biol.Chem., 2019
6OIZ
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AMYLOID-BETA (20-34) WILD TYPE
Descriptor:Amyloid beta A4 protein
Authors:Sawaya, M.R., Warmack, R.A., Zee, C.T., Gonen, T., Clarke, S.G., Eisenberg, D.S.
Deposit date:2019-04-10
Release date:2019-08-07
Method:ELECTRON CRYSTALLOGRAPHY (1.1 Å)
Cite:Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface.
Nat Commun, 10, 2019
6OJA
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CRYSTAL STRUCTURE OF THE N. MENINGITIDES METHIONINE-BINDING PROTEIN IN ITS L-METHIONINE BOUND CONFORMATION
Descriptor:Lipoprotein, METHIONINE
Authors:Nguyen, P.T., Lai, J.Y., Kaiser, J.T., Rees, D.C.
Deposit date:2019-04-11
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of the Neisseria meningitides methionine-binding protein MetQ in substrate-free form and bound to L- and D-methionine isomers.
Protein Sci., 2019
6OLQ
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), P188A MUTANT, APO STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, ACETATE ION, GLYCEROL
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-04-16
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Uncovering the molecular interactions in the catalytic loop that modulate the conformational dynamics in protein tyrosine phosphatase 1B.
J.Am.Chem.Soc., 2019
6OLV
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PROTEIN TYROSINE PHOSPHATASE 1B (1-301), P185A MUTANT, APO STATE
Descriptor:Tyrosine-protein phosphatase non-receptor type 1, GLYCEROL, ACETATE ION
Authors:Cui, D.S., Lipchock, J.M., Loria, J.P.
Deposit date:2019-04-17
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Uncovering the molecular interactions in the catalytic loop that modulate the conformational dynamics in protein tyrosine phosphatase 1B.
J.Am.Chem.Soc., 2019