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外部データベース:UniProt: Q64727 | P18206
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6FUY
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CRYSTAL STRUCTURE OF HUMAN FULL-LENGTH VINCULIN-T12-A974K (RESIDUES 1-1066)
分子名称:Vinculin, CALCIUM ION
著者Chorev, D.S., Volberg, T., Livne, A., Eisenstein, M., Martins, B., Kam, Z., Jockusch, B.M., Medalia, O., Sharon, M., Geiger, B.
登録日2018-02-28
公開日2018-03-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational states during vinculin unlocking differentially regulate focal adhesion properties.
Sci Rep, 8, 2018
5Y04
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE VINCULIN D1 DOMAIN AND ALPHAE-CATENIN
分子名称:Vinculin, Catenin alpha-1
著者Hirano, Y., Hakoshima, T.
登録日2017-07-14
公開日2018-03-28
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form
Genes Cells, 23, 2018
5L0J
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HUMAN VINCULIN R903Q, D907R, R910T MUTANT(RESIDUES 891-1066)
分子名称:Vinculin
著者Chinthalapudi, K., Izard, T.
登録日2016-07-27
公開日2016-08-31
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
5L0I
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HUMAN METAVINCULIN MVT R975W CARDIOMYOPATHY-ASSOCIATED MUTANT (RESIDUES 959-1134)
分子名称:Vinculin, GLYCEROL, SODIUM ION
著者Chinthalapudi, K., Izard, T.
登録日2016-07-27
公開日2016-08-31
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
5L0H
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HUMAN METAVINCULIN MVT CARDIOMYOPATHY-ASSOCIATED MUTANT R975W (RESIDUES 959-1134) IN COMPLEX WITH PIP2
分子名称:Vinculin, DI(HYDROXYETHYL)ETHER, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ...
著者Chinthalapudi, K., Izard, T.
登録日2016-07-27
公開日2016-08-31
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
5L0G
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HUMAN METAVINCULIN MVT Q971R, R975D, T978R MUTANT (RESIDUES 959-1134) IN COMPLEX WITH PIP2
分子名称:Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Chinthalapudi, K., Izard, T.
登録日2016-07-27
公開日2016-08-31
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
5L0F
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HUMAN METAVINCULIN QUADRUPLE MUTANT (RESIDUES 959-1134)
分子名称:Vinculin, GLYCEROL
著者Chinthalapudi, K., Izard, T.
登録日2016-07-27
公開日2016-08-31
最終更新日2016-09-07
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
5L0D
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HUMAN METAVINCULIN(RESIDUES 959-1130) IN COMPLEX WITH PIP2
分子名称:Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Chinthalapudi, K., Izard, T.
登録日2016-07-27
公開日2016-08-31
最終更新日2016-09-07
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
5L0C
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HUMAN METAVINCULIN (RESIDUES 959-1134) IN COMPLEX WITH PIP2
分子名称:Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, PHOSPHATE ION
著者Chinthalapudi, K., Izard, T.
登録日2016-07-27
公開日2016-08-31
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
4PR9
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HUMAN VINCULIN (RESIDUES 891-1066) IN COMPLEX WITH PIP
分子名称:Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, GLYCEROL
著者Chinthalapudi, K., Rangarajan, E.S., Patil, D., Izard, T.
登録日2014-03-05
公開日2014-12-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mechanism and function of lipid-directed oligomerization of vinculin
To be Published
4LNP
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THE FIRST SH3 DOMAIN FROM CAP/PONSIN IN COMPLEX WITH PROLINE RICH PEPTIDE FROM VINCULIN
分子名称:Sorbin and SH3 domain-containing protein 1, Vinculin
著者Zhao, D., Li, F., Wu, J., Shi, Y., Zhang, Z., Gong, Q.
登録日2013-07-11
公開日2014-05-28
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
4LN2
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THE SECOND SH3 DOMAIN FROM CAP/PONSIN IN COMPLEX WITH PROLINE RICH PEPTIDE FROM VINCULIN
分子名称:Sorbin and SH3 domain-containing protein 1, proline rich peptide
著者Zhao, D., Li, F., Wu, J., Shi, Y., Zhang, Z., Gong, Q.
登録日2013-07-11
公開日2014-05-28
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
4EHP
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CRYSTAL STRUCTURE OF HUMAN VINCULIN HEAD DOMAIN (RESIDUES 1-252) IN COMPLEX WITH ALPHA-CATENIN (RESIDUES 277-382)
分子名称:Vinculin, Catenin alpha-1, ACETATE ION
著者Izard, T., Rangarajan, E.S.
登録日2012-04-03
公開日2012-04-18
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献alpha-Catenin unfurls upon binding to vinculin
J.Biol.Chem., 287, 2012
4DJ9
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HUMAN VINCULIN HEAD DOMAIN VH1 (RESIDUES 1-258) IN COMPLEX WITH THE TALIN VINCULIN BINDING SITE 50 (VBS50, RESIDUES 2078-2099)
分子名称:Vinculin, Talin-1
著者Yogesha, S.D., Rangarajan, E.S., Vonrhein, C., Bricogne, G., Izard, T.
登録日2012-02-01
公開日2012-02-29
最終更新日2012-05-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin.
Protein Sci., 21, 2012
3VF0
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RAVER1 IN COMPLEX WITH METAVINCULIN L954 DELETION MUTANT
分子名称:Vinculin, Ribonucleoprotein PTB-binding 1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Lee, J.H., Vonrhein, C., Bricogne, G., Izard, T.
登録日2012-01-09
公開日2012-07-25
最終更新日2012-09-19
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献The Metavinculin Tail Domain Directs Constitutive Interactions with Raver1 and vinculin RNA.
J.Mol.Biol., 422, 2012
3TJ6
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HUMAN VINCULIN HEAD DOMAIN (VH1, RESIDUES 1-258) IN COMPLEX WITH THE VINCULIN BINDING SITE OF THE SURFACE CELL ANTIGEN 4 (SCA4-VBS-C; RESIDUES 812-835) FROM RICKETTSIA RICKETTSII
分子名称:Vinculin, Antigenic heat-stable 120 kDa protein
著者Park, H., Lee, J.H., Gouin, E., Cossart, P., Izard, T.
登録日2011-08-23
公開日2011-09-07
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
3TJ5
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HUMAN VINCULIN HEAD DOMAIN (VH1, RESIDUES 1-258) IN COMPLEX WITH THE VINCULIN BINDING SITE OF THE SURFACE CELL ANTIGEN 4 (SCA4-VBS-N; RESIDUES 412-434) FROM RICKETTSIA RICKETTSII
分子名称:Vinculin, Antigenic heat-stable 120 kDa protein, GLYCEROL
著者Park, H., Lee, J.H., Gouin, E., Cossart, P., Izard, T.
登録日2011-08-23
公開日2011-09-07
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
3S90
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HUMAN VINCULIN HEAD DOMAIN VH1 (RESIDUES 1-252) IN COMPLEX WITH MURINE TALIN (VBS33; RESIDUES 1512-1546)
分子名称:Vinculin, Talin-1
著者Yogesha, S.D., Sharff, A., Bricogne, G., Izard, T.
登録日2011-05-31
公開日2011-06-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin.
Protein Sci., 20, 2011
3RF3
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SHIGELLA IPAA-VBS3 IN COMPLEX WITH HUMAN VINCULIN
分子名称:Vinculin, Invasin ipaA, CACODYLATE ION
著者Park, H., Sharff, A., Izard, T.
登録日2011-04-05
公開日2011-04-27
最終更新日2012-05-23
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Novel vinculin binding site of the IpaA invasin of Shigella.
J.Biol.Chem., 286, 2011
3MYI
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HUMAN METAVINCULIN TAIL DOMAIN
分子名称:Vinculin
著者Izard, T., Rangarajan, E.S.
登録日2010-05-10
公開日2010-05-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A helix replacement mechanism directs metavinculin functions.
Plos One, 5, 2010
3JBK
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CRYO-EM RECONSTRUCTION OF THE METAVINCULIN-ACTIN INTERFACE
分子名称:Actin, alpha skeletal muscle, Metavinculin, ...
著者Kim, L.Y., Thompson, P.M., Lee, H.T., Pershad, M., Campbell, S.L., Alushin, G.M.
登録日2015-09-03
公開日2015-11-04
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献The Structural Basis of Actin Organization by Vinculin and Metavinculin.
J.Mol.Biol., 428, 2016
3H2V
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HUMAN RAVER1 RRM1 DOMAIN IN COMPLEX WITH HUMAN VINCULIN TAIL DOMAIN VT
分子名称:Vinculin, Raver-1
著者Lee, J.H., Rangarajan, E.S., Yogesha, S.D., Izard, T.
登録日2009-04-14
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions
Structure, 17, 2009
3H2U
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HUMAN RAVER1 RRM1, RRM2, AND RRM3 DOMAINS IN COMPLEX WITH HUMAN VINCULIN TAIL DOMAIN VT
分子名称:Vinculin, Raver-1
著者Lee, J.H., Rangarajan, E.S., Yogesha, S.D., Izard, T.
登録日2009-04-14
公開日2009-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions
Structure, 17, 2009
2IBF
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HUMAN VINCULIN'S HEAD DOMAIN (VH1, RESIDUES 1-258) IN COMPLEX WITH TWO VINCULIN BINDING SITES OF SHIGELLA FLEXNERI'S IPAA (RESIDUES 565-587)
分子名称:Vinculin, Invasin ipaA
著者Izard, T.
登録日2006-09-11
公開日2007-09-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Vinculin binding in its closed conformation by a helix addition mechanism.
Embo J., 26, 2007
2HSQ
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HUMAN VINCULIN (HEAD DOMAIN, VH1, RESIDUES 1-258) IN COMPLEX WITH SHIGELLA'S IPAA VINCULIN BINDING SITE 2 (RESIDUES 565-587)
分子名称:Vinculin, Invasin ipaA
著者Izard, T.
登録日2006-07-22
公開日2006-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.97 Å)
主引用文献Shigella applies molecular mimicry to subvert vinculin and invade host cells.
J.Cell Biol., 175, 2006
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