7Z53

Structure of native leukocyte myeloperoxidase in complex with a truncated version (SPIN truncated) of the Staphyloccal Peroxidase Inhibitor SPIN from Staphylococcus aureus

Summary for 7Z53

• Entry DOI: 10.2210/pdb7z53/pdb
• Related: 7QZR
• Descriptor: Myeloperoxidase light chain, CHLORIDE ION, HEME C, ... (17 entities in total)
• Functional Keywords: oxidoreductase, protein inhibitor, complex
• Biological source: Staphylococcus aureus; More
• Total number of polymer chains: 24
• Total formula weight: 599815.29

Authors

Pfanzagl, V.,Brito, J.A. (deposition date: 2022-03-07, release date: 2022-10-26, Last modification date: 2024-01-31)

• Primary citation: Leitgeb, U.,Furtmuller, P.G.,Hofbauer, S.,Brito, J.A.,Obinger, C.,Pfanzagl, V.; The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation.; J.Biol.Chem., 298:102514-102514, 2022; PubMed: 36150500; DOI: 10.1016/j.jbc.2022.102514

Experimental method

X-RAY DIFFRACTION (2.28 Å)