7UGP

Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 containing the N276 gp120 glycan- Class 1

Summary for 7UGP

Entry DOI	10.2210/pdb7ugp/pdb
EMDB information	26493
Descriptor	Envelope glycoprotein gp120, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp41, ... (10 entities in total)
Functional Keywords	hiv-1 env, neutralizing antibody, cd4 binding site antibody, viral protein, germline, precursor, immunogen, viral protein-immune system complex, viral protein/immune system
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	18
Total formula weight	359748.76
Authors	Dam, K.A.,Bjorkman, P.J. (deposition date: 2022-03-25, release date: 2022-11-09, Last modification date: 2022-11-16)
Primary citation	Dam, K.A.,Barnes, C.O.,Gristick, H.B.,Schoofs, T.,Gnanapragasam, P.N.P.,Nussenzweig, M.C.,Bjorkman, P.J. HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat Commun, 13:6123-6123, 2022 Cited by PubMed: 36253376 DOI: 10.1038/s41467-022-33860-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.2 Å)

Structure validation