7UCK

80S translation initiation complex with ac4c(-1) mRNA and Harringtonine

This is a non-PDB format compatible entry.

Summary for 7UCK

• Entry DOI: 10.2210/pdb7uck/pdb
• EMDB information: 26444 26445
• Descriptor: P-site tRNA, Ribosomal_L18_c domain-containing protein, 60S ribosomal protein L6, ... (82 entities in total)
• Functional Keywords: mammalian, 80s, initiation, complex, mrna modification, mrna acetylation, harringtonine, ribosome-inhibitor complex, ribosome/inhibitor
• Biological source: Oryctolagus cuniculus (rabbit); More
• Total number of polymer chains: 79
• Total formula weight: 3113436.44

Authors

Yang, R.,Arango, D.,Sturgill, D.,Oberdoerffer, S. (deposition date: 2022-03-16, release date: 2022-06-01, Last modification date: 2022-08-17)

• Primary citation: Arango, D.,Sturgill, D.,Yang, R.,Kanai, T.,Bauer, P.,Roy, J.,Wang, Z.,Hosogane, M.,Schiffers, S.,Oberdoerffer, S.; Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.; Mol.Cell, 82:2797-2814.e11, 2022; PubMed: 35679869; DOI: 10.1016/j.molcel.2022.05.016

Experimental method

ELECTRON MICROSCOPY (2.8 Å)