7SC5

Cytoplasmic tail deleted HIV Env trimer in nanodisc

Summary for 7SC5

• Entry DOI: 10.2210/pdb7sc5/pdb
• EMDB information: 25022
• Descriptor: Envelope glycoprotein gp120, Transmembrane protein gp41, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: hiv, spike, trimer, nanodisc, viral protein
• Biological source: HIV whole-genome vector AA1305#18; More
• Total number of polymer chains: 6
• Total formula weight: 244376.46

Authors

Yang, S.,Walz, T. (deposition date: 2021-09-27, release date: 2022-11-09, Last modification date: 2023-02-22)

• Primary citation: Yang, S.,Hiotis, G.,Wang, Y.,Chen, J.,Wang, J.H.,Kim, M.,Reinherz, E.L.,Walz, T.; Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack.; Nat Commun, 13:6393-6393, 2022; PubMed: 36302771; DOI: 10.1038/s41467-022-34008-y

Experimental method

ELECTRON MICROSCOPY (3.88 Å)