7GCH

STRUCTURE OF CHYMOTRYPSIN-*TRIFLUOROMETHYL KETONE INHIBITOR COMPLEXES. COMPARISON OF SLOWLY AND RAPIDLY EQUILIBRATING INHIBITORS

Summary for 7GCH

Entry DOI	10.2210/pdb7gch/pdb
Descriptor	GAMMA-CHYMOTRYPSIN A, 1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE), ... (5 entities in total)
Functional Keywords	hydrolase (serine proteinase)
Biological source	Bos taurus (cattle) More
Cellular location	Secreted, extracellular space: P00766 P00766 P00766
Total number of polymer chains	3
Total formula weight	25634.94
Authors	Brady, K.,Ringe, D.,Abeles, R.H. (deposition date: 1990-04-06, release date: 1990-10-15, Last modification date: 2011-07-13)
Primary citation	Brady, K.,Wei, A.Z.,Ringe, D.,Abeles, R.H. Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors. Biochemistry, 29:7600-7607, 1990 Cited by PubMed: 2271520 DOI: 10.1021/bi00485a009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation