6ZWI

Human butyrylcholinesterase in complex with ((6-((2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienamido)hexyl)triphenylphosphonium bromide)

Summary for 6ZWI

• Entry DOI: 10.2210/pdb6zwi/pdb
• Descriptor: Cholinesterase, CHLORIDE ION, SULFATE ION, ... (13 entities in total)
• Functional Keywords: butyrylcholinesterase, inhibitor, mitochondria, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 64474.36

Authors

Da Silva, O.,Nachon, F.,Dias, J.,Brazzolotto, X. (deposition date: 2020-07-28, release date: 2021-06-09, Last modification date: 2024-01-31)

• Primary citation: Chavarria, D.,Da Silva, O.,Benfeito, S.,Barreiro, S.,Garrido, J.,Cagide, F.,Soares, P.,Remiao, F.,Brazzolotto, X.,Nachon, F.,Oliveira, P.J.,Dias, J.,Borges, F.; Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases.; Antioxidants (Basel), 10:-, 2021; PubMed: 33672269; DOI: 10.3390/antiox10020329

Experimental method

X-RAY DIFFRACTION (1.85 Å)