6WX9

SOX2 bound to Importin-alpha 5

Summary for 6WX9

• Entry DOI: 10.2210/pdb6wx9/pdb
• Descriptor: Importin subunit alpha-5, Transcription factor SOX-2 (3 entities in total)
• Functional Keywords: importin, sox2, nuclear protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 62770.95

Authors

Bikshapathi, J.,Stewart, M.,Forwood, J.K.,Aragao, D.,Roman, N. (deposition date: 2020-05-10, release date: 2020-10-28, Last modification date: 2023-10-25)

• Primary citation: Jagga, B.,Edwards, M.,Pagin, M.,Wagstaff, K.M.,Aragao, D.,Roman, N.,Nanson, J.D.,Raidal, S.R.,Dominado, N.,Stewart, M.,Jans, D.A.,Hime, G.R.,Nicolis, S.K.,Basler, C.F.,Forwood, J.K.; Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.; Nat Commun, 12:28-28, 2021; PubMed: 33397924; DOI: 10.1038/s41467-020-20194-0

Experimental method

X-RAY DIFFRACTION (2.8 Å)