6UI9

Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate

Summary for 6UI9

• Entry DOI: 10.2210/pdb6ui9/pdb
• EMDB information: 20783
• Descriptor: ACLY, ACETYL COENZYME *A, OXALOACETATE ION, ... (4 entities in total)
• Functional Keywords: lyase
• Biological source: Homo sapiens
• Total number of polymer chains: 4
• Total formula weight: 488223.36

Authors

Wei, X.,Marmorstein, R. (deposition date: 2019-09-30, release date: 2019-12-25, Last modification date: 2024-03-20)

• Primary citation: Wei, X.,Schultz, K.,Bazilevsky, G.A.,Vogt, A.,Marmorstein, R.; Molecular basis for acetyl-CoA production by ATP-citrate lyase; Nat.Struct.Mol.Biol., 27:33-41, 2020; PubMed: 31873304; DOI: 10.1038/s41594-019-0351-6

Experimental method

ELECTRON MICROSCOPY (3.1 Å)