6U48

E. coli 50S with phazolicin (PHZ) bound in exit tunnel

This is a non-PDB format compatible entry.

Summary for 6U48

• Entry DOI: 10.2210/pdb6u48/pdb
• EMDB information: 20638
• Related PRD ID: PRD_002365
• Descriptor: 23S rRNA, 50S ribosomal protein uL13, 50S ribosomal protein uL14, ... (32 entities in total)
• Functional Keywords: ribosome, phazolicin, antimicrobial protein, ribosome-inhibitor complex, ribosome/inhibitor
• Biological source: Escherichia coli; More
• Total number of polymer chains: 32
• Total formula weight: 1352665.05

Authors

Watson, Z.L.,Cate, J.H.D.,Polikanov, Y.S.,Severinov, K. (deposition date: 2019-08-23, release date: 2019-09-18, Last modification date: 2023-11-15)

• Primary citation: Travin, D.Y.,Watson, Z.L.,Metelev, M.,Ward, F.R.,Osterman, I.A.,Khven, I.M.,Khabibullina, N.F.,Serebryakova, M.,Mergaert, P.,Polikanov, Y.S.,Cate, J.H.D.,Severinov, K.; Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition.; Nat Commun, 10:4563-4563, 2019; PubMed: 31594941; DOI: 10.1038/s41467-019-12589-5

Experimental method

ELECTRON MICROSCOPY (2.87 Å)