6S9M

Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKITW

Summary for 6S9M

• Entry DOI: 10.2210/pdb6s9m/pdb
• Related: 6S9L
• Descriptor: Lock2_KRKRKAKITW, CALCIUM ION, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: peptide binder, repeat protein, designed armadillo repeat protein, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 6
• Total formula weight: 191575.90

Authors

Ernst, P.,Zosel, F.,Reichen, C.,Schuler, B.,Pluckthun, A. (deposition date: 2019-07-15, release date: 2020-02-19, Last modification date: 2020-03-04)

• Primary citation: Ernst, P.,Zosel, F.,Reichen, C.,Nettels, D.,Schuler, B.,Pluckthun, A.; Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.; Acs Chem.Biol., 15:457-468, 2020; PubMed: 31985201; DOI: 10.1021/acschembio.9b00928

Experimental method

X-RAY DIFFRACTION (2 Å)