6S9L

Designed Armadillo Repeat protein Lock1 bound to (KR)4KLSF target

Summary for 6S9L

Entry DOI	10.2210/pdb6s9l/pdb
Descriptor	KR4KLSF Lock1, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-LEU-SER-PHE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
Functional Keywords	peptide binder, repeat protein, designed armadillo repeat protein, de novo protein
Biological source	synthetic construct More
Total number of polymer chains	4
Total formula weight	63876.12
Authors	Ernst, P.,Zosel, F.,Reichen, C.,Schuler, B.,Pluckthun, A. (deposition date: 2019-07-15, release date: 2020-02-19, Last modification date: 2020-03-04)
Primary citation	Ernst, P.,Zosel, F.,Reichen, C.,Nettels, D.,Schuler, B.,Pluckthun, A. Structure-Guided Design of a Peptide Lock for Modular Peptide Binders. Acs Chem.Biol., 15:457-468, 2020 Cited by PubMed: 31985201 DOI: 10.1021/acschembio.9b00928 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation