6Q5A

Crystal structure of Cryptosporidium hominis CPSF3 in the apo form

Summary for 6Q5A

Entry DOI	10.2210/pdb6q5a/pdb
Related	6Q55
Descriptor	Cleavage and Polyadenylation Specificity Factor 3, ZINC ION, GLYCEROL, ... (7 entities in total)
Functional Keywords	mrna processing factor, metallo-beta-lactamase, beta-casp, oxaborole-inhibitor, rna binding protein
Biological source	Cryptosporidium hominis
Total number of polymer chains	1
Total formula weight	54723.86
Authors	Palencia, A.,Swale, C. (deposition date: 2018-12-07, release date: 2019-11-20, Last modification date: 2024-01-24)
Primary citation	Swale, C.,Bougdour, A.,Gnahoui-David, A.,Tottey, J.,Georgeault, S.,Laurent, F.,Palencia, A.,Hakimi, M.A. Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection. Sci Transl Med, 11:-, 2019 Cited by PubMed: 31694928 DOI: 10.1126/scitranslmed.aax7161 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation