6Q0J

Structure of a MAPK pathway complex

Summary for 6Q0J

• Entry DOI: 10.2210/pdb6q0j/pdb
• EMDB information: 20550
• Descriptor: Serine/threonine-protein kinase B-raf, Dual specificity mitogen-activated protein kinase kinase 1, 14-3-3 protein zeta, ... (6 entities in total)
• Functional Keywords: transferase, transferase-protein binding complex, transferase/protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 328707.26

Authors

Park, E.,Rawson, S.,Jeon, H.,Eck, M.J. (deposition date: 2019-08-01, release date: 2019-10-09, Last modification date: 2020-04-22)

• Primary citation: Park, E.,Rawson, S.,Li, K.,Kim, B.W.,Ficarro, S.B.,Pino, G.G.,Sharif, H.,Marto, J.A.,Jeon, H.,Eck, M.J.; Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.; Nature, 575:545-550, 2019; PubMed: 31581174; DOI: 10.1038/s41586-019-1660-y

Experimental method

ELECTRON MICROSCOPY (4.9 Å)