6PAD

Binding of chloromethyl ketone substrate analogues to crystalline papain

Replaces:  7PAP

Summary for 6PAD

• Entry DOI: 10.2210/pdb6pad/pdb
• Related: 1PAD 2PAD 4PAD 5PAD
• Related PRD ID: PRD_000333
• Descriptor: PAPAIN, Nalpha-[(benzyloxy)carbonyl]-N-[(1S)-3-chloro-1-methyl-2-oxopropyl]-L-phenylalaninamide (3 entities in total)
• Functional Keywords: sulfhydryl proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Carica papaya (papaya)
• Total number of polymer chains: 1
• Total formula weight: 23852.22

Authors

Drenth, J.,Kalk, K.H.,Swen, H.M. (deposition date: 1976-11-01, release date: 1977-04-12, Last modification date: 2023-09-27)

• Primary citation: Drenth, J.,Kalk, K.H.,Swen, H.M.; Binding of chloromethyl ketone substrate analogues to crystalline papain.; Biochemistry, 15:3731-3738, 1976; PubMed: 952885; DOI: 10.1021/bi00662a014

Experimental method

X-RAY DIFFRACTION (2.8 Å)