6P95

Structure of Lassa virus glycoprotein in complex with Fab 25.6A

Summary for 6P95

• Entry DOI: 10.2210/pdb6p95/pdb
• Related: 6P91
• Descriptor: Pre-glycoprotein polyprotein GP complex, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: lassa virus, glycoprotein, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Lassa virus (LASV); More
• Total number of polymer chains: 12
• Total formula weight: 305481.89

Authors

Saphire, E.O.,Hastie, K.M. (deposition date: 2019-06-09, release date: 2019-09-11, Last modification date: 2023-10-11)

• Primary citation: Hastie, K.M.,Cross, R.W.,Harkins, S.S.,Zandonatti, M.A.,Koval, A.P.,Heinrich, M.L.,Rowland, M.M.,Robinson, J.E.,Geisbert, T.W.,Garry, R.F.,Branco, L.M.,Saphire, E.O.; Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization.; Cell, 178:1004-1015.e14, 2019; PubMed: 31398326; DOI: 10.1016/j.cell.2019.07.020

Experimental method

X-RAY DIFFRACTION (3.5 Å)