6OU3

Crystal Structure of the D478S Variant of the Myocilin Olfactomedin Domain

Summary for 6OU3

Entry DOI	10.2210/pdb6ou3/pdb
Descriptor	Myocilin, SODIUM ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	olfactomedin myocilin beta propeller, protein binding
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	31376.15
Authors	Hill, S.E.,Kwon, M.S.,Lieberman, R.L. (deposition date: 2019-05-03, release date: 2019-07-03, Last modification date: 2020-01-15)
Primary citation	Hill, S.E.,Kwon, M.S.,Martin, M.D.,Suntharalingam, A.,Hazel, A.,Dickey, C.A.,Gumbart, J.C.,Lieberman, R.L. Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations. J.Biol.Chem., 294:12717-12728, 2019 Cited by PubMed: 31270212 DOI: 10.1074/jbc.RA119.009419 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.796 Å)

Structure validation