6OF5

The crystal structure of dodecyloxy(naphthalen-1-yl)methylphosphonic acid in complex with red kidney bean purple acid phosphatase

Summary for 6OF5

• Entry DOI: 10.2210/pdb6of5/pdb
• Descriptor: Fe(3+)-Zn(2+) purple acid phosphatase, SODIUM ION, 1,2-ETHANEDIOL, ... (15 entities in total)
• Functional Keywords: purple acid phosphatase, metallohydrolases, transition state, catalysis, osteoporosis, metal binding protein
• Biological source: Phaseolus vulgaris (Kidney bean)
• Total number of polymer chains: 4
• Total formula weight: 210944.78

Authors

Feder, D.,Schenk, G.,Guddat, L.W.,Hussein, W.M.,McGeary, R.P. (deposition date: 2019-03-28, release date: 2019-09-04, Last modification date: 2023-10-11)

• Primary citation: Feder, D.,Kan, M.W.,Hussein, W.M.,Guddat, L.W.,Schenk, G.,McGeary, R.P.; Synthesis, evaluation and structural investigations of potent purple acid phosphatase inhibitors as drug leads for osteoporosis.; Eur.J.Med.Chem., 182:111611-111611, 2019; PubMed: 31445230; DOI: 10.1016/j.ejmech.2019.111611

Experimental method

X-RAY DIFFRACTION (2.3 Å)