6O69

Crystal Structure of Double Mutant L380R/F535K of Human Acetylcholinesterase

Summary for 6O69

• Entry DOI: 10.2210/pdb6o69/pdb
• Descriptor: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 60043.69

Authors

Bester, S.M.,Height, J.J.,Pegan, S.D. (deposition date: 2019-03-05, release date: 2019-05-01, Last modification date: 2023-10-11)

• Primary citation: Bester, S.M.,Adipietro, K.A.,Funk, V.L.,Myslinski, J.M.,Keul, N.D.,Cheung, J.,Wilder, P.T.,Wood, Z.A.,Weber, D.J.,Height, J.J.,Pegan, S.D.; The structural and biochemical impacts of monomerizing human acetylcholinesterase.; Protein Sci., 28:1106-1114, 2019; PubMed: 30993792; DOI: 10.1002/pro.3625

Experimental method

X-RAY DIFFRACTION (2.081 Å)